Cytokine gene polymorphisms in multifactorial conditions / edited by Koen Vandenbroeck.

Format:

Book

Contributor:

Vandenbroeck, Koen.

Language:

English

Subjects (All):

Immunology.

Cytokines.

Gene targeting.

Genetic Predisposition to Disease.

Immunity--genetics.

Multifactorial Inheritance--genetics.

Polymorphism, Genetic.

Medical Subjects:

Cytokines.

Genetic Predisposition to Disease.

Immunity--genetics.

Multifactorial Inheritance--genetics.

Polymorphism, Genetic.

Physical Description:

459 pages : illustrations ; 26 cm

Place of Publication:

Boca Raton, FL : CRC Taylor & Francis, 2006.

Summary:

Written by the leading specialists, this book brings together, reviews, and structures up-to-date information on polymorphisms in cytokine genes. While the beginning chapters discuss the properties of individual cytokines, in the later chapters cytokine polymorphisms are re-presented considering the individual disease or condition. Broadening understanding of the effect of genetic variations on human immune responses, the organization, scope, and content of this book make it a valuable and easily accessible resource. A reference for geneticists, immunologists, cell and molecular biologists and clinicians, the book is a must for everyone involved in, or planning, cytokine genetics or immunogenetics studies.

Contents:

The biology of cytokines: general principles, properties and lessons from animal models / Davide Agnello and Massimo Gadina

Genetics of multifactorial disorders / Jorge R. Oksenberg and John D. Rioux

Statistical approaches to analysis of polymorphisms in multifactorial disorders / An Goris and Mariza de Andrade

Introduction to integrated bioinformatic resources for cytokine genetics research / Ross Lazarus

Cytokine gene nucleotide sequence alignments / Jeffrey Bidwell

SNP genotyping techniques / Pui-Yan Kwok

The IL1 cluster / Tanja Pessi ... [et al.]

IL-2 biology and polymorphisms in multifactorial conditions / Fuencisla Matesanz, María Fedetz, and Antonio Alcina

The chromosome 5q23.1-q31.1 cluster of cytokines / Tarja Laitinen

IL10 / Ross Lazarus

The IL19 subfamily of cytokines / Sulev Kõks ... [et al.]

The IFNG-IL26-IL22 cytokine gene cluster / Koen Vandenbroeck and An Goris

TNF polymorphisms and disease / Reginald M. Gorczynski and Ivo Boudakov

Macrophage migration inhibitory factor (MIF) / Zaynab Alourfi, David W. Ray, and Rachelle Donn

Polymorphisms of chemokines and their receptors / Bénédicte Puissant, Christophe Combadière, and Elise Lavergne

Asthma and atopy / Jussi Karjalainen ... [et al.]

Common rheumatic diseases / Rachael Kilding and Anthony G. Wilson

Systemic lupus erythematosus / Sandra D'Alfonso

Sjögren's syndrome / Marja Pertovaara

Multiple sclerosis / Orhun H. Kantarci and Brian G. Weinshenker

Type 1 and 2 diabetes / Regine Bergholdt and Flemming Pociot

Psoriasis / Sulev Kõks ... [et al.]

Diseases of the gastrointestinal tract / Thomas Höhler

Pulmonary fibrosis / Berran Yucesoy and Michael I. Luster

Atherosclerosis / Giuseppina Candore ... [et al.]

Longevity / Irene Maeve Rea ... [et al.]

AIDS / Alexandre Vasilescu, Hervé Do, and Jean-Francois Zagury

Tropical infectious diseases / Thereza Quirico-Santos ... [et al.]

Suseptibility to infection and severe disease in schistosomiasis / Violaine Arnaud and Christophe Chevillard.

Notes:

Includes bibliographical references and index.

ISBN:

0849336198

OCLC:

62759354

Publisher Number:

9780849336195

Online:

Publisher description