Retinal development / edited by Evelyne Sernagor ... [and others].

Format:

Book

Contributor:

Sernagor, Evelyne.

Language:

English

Subjects (All):

Retina--Growth.

Retina.

Eye--Differentiation.

Eye.

Vertebrates--Physiology.

Vertebrates.

Developmental biology.

Retina--growth & development.

Eye--cytology.

Medical Subjects:

Retina--growth & development.

Eye--cytology.

Physical Description:

xvi, 383 pages, 8 unnumbered pages of plates : illustrations (some color) ; 26 cm

Place of Publication:

Cambridge ; New York : Cambridge University Press, 2006.

Summary:

Retinal Development takes a developmental approach to the presentation of our current understanding of how vertebrates construct a retina. The book starts by examining how a patch of ectoderm becomes committed to make the eyes. It proceeds through the generation of the retinal neurons and how they connect up, culminating in the emergence of the first light responses. Written by experts in the field, each chapter covers a specific step in this process, focusing on the underlying molecular, cellular and physiological mechanisms. There is also a special section on the emerging technologies such as genomics, zebrafish genetics and stem cell biology that are starting to yield important new insights into retinal development. Primarily aimed at professionals, both biologists and clinicians working with the retina, this book provides a concise and up-to-date view of what is known about vertebrate retinal development. Since the retina is 'an approachable part of the brain', this book is also attractive to all neuroscientists interested in development, as processes required to build this exquisitely organized system are ultimately relevant to all other parts of the central nervous system.

Contents:

1 Introduction - from eye field to eyesight / Rachel O. L. Wong 1

2 Formation of the eye field / Michael E. Zuber, William A. Harris 8

3 Retinal neurogenesis / David H. Rapaport 30

4 Cell migration / Leanne Godinho, Brian Link 59

5 Cell determination / Michalis Agathocleous, William A. Harris 75

6 Neurotransmitters and neurotrophins / Rachael A. Pearson 99

7 Comparison of development of the primate fovea centralis with peripheral retina / Anita Hendrickson, Jan Provis 126

8 Optic nerve formation / David W. Sretavan 150

9 Glial cells in the developing retina / Kathleen Zahs, Manuel Esguerra 172

10 Retinal mosaics / Stephen J. Eglen, Lucia Galli-Resta 193

11 Programmed cell death / Rafael Linden, Benjamin E. Reese 208

12 Dendritic growth / Jeff Mumm, Christian Lohmann 242

13 Synaptogenesis and early neural activity / Evelyne Sernagor 265

14 Emergence of light responses / Evelyne Sernagor, Leo M. Chalupa 288

New perspectives

15 Regeneration: transdifferentiation and stem cells / Jennie Leigh Close, Thomas A. Reh 307

16 Genomics / Seth Blackshaw 325

17 Zebrafish models of retinal development and disease / James M. Fadool, John E. Dowling 342.

Notes:

Includes bibliographical references and index.

ISBN:

0521837987

OCLC:

70671782

Publisher Number:

9780521837989