Optical coherence tomography : principles and applications / Mark E. Brezinski.

Format:

Book

Author/Creator:

Brezinski, Mark E.

Language:

English

Subjects (All):

Optical tomography.

Optical tomography--Technological innovations.

Tomography, Optical Coherence.

Technological innovations.

Medical Subjects:

Tomography, Optical Coherence.

Physical Description:

xxvii, 599 pages, 16 unnumbered pages of plates : illustrations (some color) ; 25 cm

Place of Publication:

Amsterdam ; Boston : Elsevier Academic Press, [2006]

Summary:

Optical Coherence Tomography, the most comprehensive work on Optical Coherence Tomography (OCT), is organized into three interrelated sections. Section one provides non-physical scientists with an understanding of the basic physics and mathematics utilized in OCT studies. The second section discusses the physics and engineering of OCT technology including the theoretical derivation of axial and lateral resolution generated with OCT, a comprehensive analysis of sources of dynamic range including loss from classical to quantum noise, CCD, A-D conversion, and detailed comparisons of spectral and TD techniques. In addition, topics discussed in detail include photon entanglement, phase analysis, and dispersion analysis for tissue characterization. Section three details the application of OCT to clinical pathologies and techniques with a review of epidemiology, pathophysiology, competing technologies, and factors affecting decisions on clinical utility and therapies. Details of application range from techniques used to characterize tissue, such as special staining and high pressure liquid chromatography, to factors affecting the validity of clinical trails, including sources of bias and trial types. Techniques for effective hypothesis testing in both basic and clinical studies are discussed in detail.

Contents:

The basics (math, waves, etc.) for the nonphysical scientist

Light and electromagnetic waves

Light in matter

Interference, coherence, diffraction, and transfer functions

Optical coherence tomography theory

Optoelectronics and optical components

Noise and system performance with TD-OCT and SD-OCT

Polarization and polarization sensitive OCT

Adjuvant techniques: absorption spectroscopy, contrast probes, phase contrast, elastography, and entangled photons

Doppler optical coherence tomography / Bin Liu

Digital image processing techniques for speckle reduction, enhancement, and segmentation of optical coherence tomography (OCT) images / Jadwiga Togowska

Application of OCT to clinical imaging: introduction

Other technologies

Introduction to clinical research design and analysis / Kelly Jenkins and Kimberlee Gauvreau

OCT in cardiovascular medicine

OCT in musculoskeletal disease

OCT in oncology

Other applications and conclusions.

Notes:

Includes bibliographical references and index.

ISBN:

0121335704

OCLC:

64589074

Publisher Number:

9780121335700

Online:

Publisher description