Principles of psychopharmacology for mental health professionals / Jeffrey E. Kelsey, D. Jeffrey Newport, Charles B. Nemeroff.

Format:

Book

Author/Creator:

Kelsey, Jeffrey E.

Contributor:

Newport, D. Jeffrey.

Nemeroff, Charles B.

Language:

English

Subjects (All):

Mental illness--Chemotherapy.

Mental illness.

Psychopharmacology.

Psychopharmacology--methods.

Mental Disorders.

Psychotropic Drugs--therapeutic use.

Medical Subjects:

Psychopharmacology--methods.

Mental Disorders.

Psychotropic Drugs--therapeutic use.

Physical Description:

xix, 389 pages : illustrations ; 24 cm

Place of Publication:

Hoboken, N.J. : Wiley-Liss, [2006]

Summary:

Principles of Psychopharmacology for Mental Health Professionals addresses the current "split" model of mental health care, in which physicians provide pharmaco-therapy while non-prescribing practitioners oversee other services such as psychotherapy. Bringing these two areas together, this book familiarizes mental health professionals with the medications used to treat psychiatric disorders.

Prepared by world-renowned psychopharmacologists and psychiatrists, this useful resource helps non-prescribing practitioners understand when and why a given medication is appropriate to use, when it is not indicated, and what potential side effects may occur. Also discussed are the appropriate times in therapy when a referral for a medication evaluation is indicated as well as how to broach this issue with the patient. Recognizing that there are almost always a number of medications from which to choose, the authors combine research outcomes with their extensive clinical experience to highlight the important considerations in selecting one medication over another. As an educational tool, the text encourages and supports clinicians who wish to increase patients' understanding of treatment.

Principles of Psychopharmacology for Mental Health Professionals lays out what psychotherapists and other mental health practitioners need to know about psychotropic medications, giving them and their patients an invaluable guide to the full array of treatments available.

Contents:

Faculty Disclosure xvii

2 Basics of Psychopharmacology 9

2.1.1 Learning the Language of Pharmacology 9

2.2 Normal Human Nervous System 10

2.2.1 Neuroanatomy: Structure of the Nervous System 11

2.2.2 Neurophysiology: Function of the Nervous System 14

2.3 Pathophysiology: Study of What Goes Wrong 19

2.3.1 What Goes Wrong 20

2.3.2 Why It Goes Wrong 21

2.4 Pharmacology 22

2.4.2 Pharmacokinetics 23

2.4.3 Pharmacodynamics 26

2.4.4 Predicting Medication Effects 29

2.4.5 Predicting Drug Interactions 30

3 Mood Disorders 37

3.2 Major Depressive Disorder 39

3.2.1 Brief Description and Diagnostic Criteria 39

3.2.2 Prevalence and Risk Factors 40

3.2.3 Presentation and Clinical Course 41

3.2.4 Initial Evaluation and Differential Diagnosis 42

3.2.5 History of Pharmacological Treatment 46

3.2.6 Current Approach to Treatment 60

3.2.7 Refractory Depression 66

3.3 Dysthymic Disorder 68

3.3.1 Brief Description and Diagnostic Criteria 68

3.3.2 Prevalence and Risk Factors 68

3.3.3 Presentation and Clinical Course 68

3.3.4 Initial Evaluation and Differential Diagnosis 69

3.3.5 History of Pharmacological Treatment 69

3.3.6 Current Approach to Treatment 70

3.3.7 Refractory Depression 70

3.4 Bipolar Disorders 71

3.4.1 Brief Description and Diagnostic Criteria 71

3.4.2 Prevalence and Risk Factors 73

3.4.3 Presentation and Clinical Course 73

3.4.4 Initial Evaluation and Differential Diagnosis 74

3.4.5 History of Pharmacological Treatment 78

3.4.6 Current Approach to Treatment 87

4 Schizophrenia 97

4.1 Brief Description and Diagnostic Criteria 97

4.2 Prevalence and Risk Factors 100

4.3 Presentation and Clinical Course 100

4.4 Initial Evaluation and Differential Diagnosis 102

4.5 History of Treatment 107

4.6 Current Approach to Treatment 120

4.6.1 Prodromal Phase 120

4.6.2 Acute Phase 121

4.6.3 Maintenance Phase 123

4.6.4 Residual Phase 124

4.7 Treatment Resistant Schizophrenia 124

5 Anxiety Disorders 127

5.1.1 History of Anxiety Disorders 127

5.1.2 Anxiety Symptoms 128

5.1.3 Brief Overview of the Anxiety Disorders 129

5.1.4 History of Pharmacological Treatment for Anxiety 130

5.2 Panic Disorder 136

5.2.1 Brief Description and Diagnostic Criteria 136

5.2.2 Prevalence and Risk Factors 138

5.2.3 Presentation and Clinical Course 138

5.2.4 Initial Evaluation and Differential Diagnosis 139

5.2.5 History of Pharmacological Treatment 141

5.2.6 Current Approach to Treatment 143

5.3 Generalized Anxiety Disorder 145

5.3.1 Brief Description and Diagnostic Criteria 145

5.3.2 Prevalence and Risk Factors 145

5.3.3 Presentation and Clinical Course 146

5.3.4 Initial Evaluation and Differential Diagnosis 146

5.3.5 History of Pharmacological Treatment 148

5.3.6 Current Approach of Treatment 151

5.4 Obsessive-Compulsive Disorder 152

5.4.1 Brief Description and Diagnostic Criteria 152

5.4.2 Prevalence and Risk Factors 153

5.4.3 Presentation and Clinical Course 154

5.4.4 Initial Evaluation and Differential Diagnosis 155

5.4.5 History of Pharmacological Treatment 156

5.4.6 Current Approach to Treatment 158

5.5 Social Anxiety Disorder (Social Phobia) 159

5.5.1 Brief Description and Diagnostic Criteria 159

5.5.2 Prevalence and Risk Factors 160

5.5.3 Presentation and Clinical Course 160

5.5.4 Initial Evaluation and Differential Diagnosis 161

5.5.5 History of Pharmacological Treatment 162

5.5.6 Current Approach to Treatment 166

5.6 Post-Traumatic Stress Disorder 167

5.6.1 Brief Description and Diagnostic Criteria 167

5.6.2 Prevalence and Risk Factors 168

5.6.3 Presentation and Clinical Course 169

5.6.4 Initial Evaluation and Differential Diagnosis 170

5.6.5 History of Pharmacological Treatment 171

5.6.6 Current Approach to Treatment 174

6 Substance Use Disorders 177

6.1.1 The Illness Model of Substance Abuse 177

6.2 Brief Description and Diagnostic Criteria 180

6.3 Prevalence and Risk Factors 183

6.4 Presentation and Clinical Course 184

6.5 Initial Evaluation and Differential Diagnosis 186

6.6 History of Treatment 188

6.7 Current Approaches to Treatment 190

6.8 Alcohol Use Disorders 192

6.8.1 History of Treatment 192

6.8.2 Current Approach to Treatment 197

6.9 Cocaine Use Disorders 198

6.9.1 History of Treatment 198

6.9.2 Current Approach to Treatment 199

6.10 Nicotine Dependence 200

6.10.1 History of Treatment 200

6.10.2 Current Approach to Treatment 201

6.11 Opiate Use Disorders 201

6.11.1 History of Treatment 201

6.11.2 Current Approach to Treatment 205

7 Eating Disorders 207

7.2 Anorexia Nervosa 209

7.2.1 Brief Description and Diagnostic Criteria 209

7.2.2 Prevalence and Risk Factors 210

7.2.3 Presentation and Clinical Course 211

7.2.4 Initial Evaluation and Differential Diagnosis 211

7.2.5 History of Pharmacological Treatment 213

7.2.6 Current Approach to Treatment 216

7.3 Bulimia Nervosa 217

7.3.1 Brief Description and Diagnostic Criteria 217

7.3.2 Prevalence and Risk Factors 218

7.3.3 Presentation and Clinical Course 219

7.3.4 Initial Evaluation and Differential Diagnosis 220

7.3.5 History of Pharmacological Treatment 221

7.3.6 Current Approach to Treatment 222

7.3.7 Patients with Refractory Disease 223

7.4 Binge-Eating Disorder 224

7.4.1 Brief Description and Diagnostic Criteria 224

7.4.2 Prevalence and Risk Factors 225

7.4.3 Presentation and Clinical Course 225

7.4.4 Initial Evaluation and Differential Diagnosis 225

7.4.5 History of Pharmacological Treatment 226

7.4.6 Current Approach to Treatment 228

8 Attention Deficit-Hyperactivity Disorder 231

8.1 Brief Description and Diagnostic Criteria 231

8.2 Prevalence and Risk Factors 233

8.3 Presentation and Clinical Course 235

8.4 Initial Evaluation and Differential Diagnosis 236

8.5 History of Pharmacological Treatment 239

8.6 Current Approach to Treatment 249

9 Sleep Disorders 257

9.1.1 Normal Sleep 258

9.1.2 Overview of Sleep Disorders 259

9.2 Insomnia 260

9.2.1 Brief Description and Diagnostic Criteria 260

9.2.2 Prevalence and Risk Factors 261

9.2.3 Presentation and Clinical Course 262

9.2.4 Initial Evaluation and Differential Diagnosis 262

9.2.5 History of Pharmacological Treatment 266

9.2.6 Current Approach to Treatment 273

9.3 Narcolepsy 275

9.3.1 Brief Description and Diagnostic Criteria 275

9.3.2 Prevalence and Risk Factors 276

9.3.3 Presentation and Clinical Course 276

9.3.4 Initial Evaluation and Differential Diagnosis 277

9.3.5 History of Pharmacological Treatment 277

9.3.6 Current Approach to Treatment 280

10 Alzheimer's Disease and Other Dementias 283

10.1 Brief Description and Diagnostic Criteria 283

10.2 Prevalence and Risk Factors 285

10.2.1 Causes of Dementia 286

10.2.2 Risk Factors for Dementia 287

10.3 Presentation and Clinical Course 288

10.4 Initial Evaluation and Differential Diagnosis 289

10.4.1 Initial Evaluation 289

10.4.2 Differential Diagnosis 290

10.5 History of Pharmacological Treatment 293

10.5.1 Overview and Current Theory 293

10.5.2 Historical Treatment Strategies 294

10.5.3 History of Dementia Reversal Treatments 295

10.5.4 History of Brain Protection Treatments 296

10.5.5 History of Cognitive Enhancement Treatments 297

10.5.6 History of Behavioral Management Treatments 301

10.6 Current Approach to Treatment 303

10.6.1 Current Treatment Options at Different Stages of Dementia 304

10.6.2 Current Options for Cognitive Enhancement 305

10.6.3 Current Options for Brain Protection 305

10.6.4 Current Options for Treatment of Behavioral and Emotional Problems 306

11 Personality Disorders 313

11.1.1 How Little We Know 313

11.1.2 Defining a Personality Disorder 315

11.1.3 Prerequisites to Beginning Treatment 316

11.2 Cluster A: Odd and Eccentric Personality Disorders 317

11.2.1 Brief Description and Diagnostic Criteria 317

11.2.2 Prevalence and Risk Factors 318

11.2.3 Initial Evaluation and Differential Diagnosis 318

11.2.4 History of Pharmacological Treatment 320

11.2.5 Current Approach to Treatment 321

11.3 Cluster B: Dramatic and Emotional Personality Disorders 322

11.3.1 Brief Description and Diagnostic Criteria 322

11.3.2 Prevalence and Risk Factors 323

11.3.3 Initial Evaluation and Differential Diagnosis 324

11.3.4 History of Pharmacological Treatment 326

11.3.5 Current Approach to Treatment 329

11.4 Cluster C: Anxious and Fearful Personality Disorders 331

11.4.1 Brief Description and Diagnostic Criteria 331

11.4.2 Prevalence and Risk Factors 332

11.4.3 Initial Evaluation and Differential Diagnosis 332

11.4.4 History of Pharmacological Treatment 333

11.4.5 Current Approach to Treatment 335

12 Traumatic Brain Injury 337

12.1.1 Brief Description and Diagnostic Criteria 337

12.1.2 Prevalence and Risk Factors 337

12.1.3 Presentation and Clinical Course 338

12.1.4 Initial Evaluation and Differential Diagnosis 340

12.2 Approaches to Treatment 341

12.2.1 Post-TBI Depression 341

12.2.2 Post-TBI Apathy 342

12.2.3 Post-TBI Mania 344

12.2.4 Post-TBI Psychosis 346

12.2.5 Post-TBI Anxiety 347

12.2.6 Post-TBI Dementia and Delirium 348

12.2.7 Post-TBI Behavioral Disturbances 349

13 Managing Side Effects 353

13.1.1 Organizing This Discussion 353

13.1.2 Recognizing Side Effects 355

13.1.3 General Approach to Managing Side Effects 358

13.2 Norepinephrine-Related Side Effects 360

13.2.1 Side Effects of Norepinephrine-Boosting Medications 360

13.2.2 Side Effects of Norepinephrine-Blocking Medications 362

13.3 Dopamine-Related Side Effects 363

13.3.1 Side Effects of Dopamine-Boosting Medications 363

13.3.2 Side Effects of Dopamine-Blocking Medications 365

13.4 Serotonin-Related Side Effects 371

13.4.1 Side Effects of Serotonin-Boosting Medications 371

13.4.2 Side Effects of Serotonin-Blocking Medications 375

13.5 GABA-Related Side Effects 376

13.5.1 Side Effects of GABA Boosting Medications 376

13.5.2 Side Effects of GABA-Blocking Medications 377

13.6 Acetylcholine-Related Side Effects 377

13.6.1 Side Effects of Acetylcholine-Boosting Medications 377

13.6.2 Side Effects of Acetylcholine-Blocking Medications 378

13.7 Histamine-Related Side Effects 379

13.7.1 Side Effects of Histamine-Blocking Medications 379.

Notes:

Includes bibliographical references and index.

ISBN:

0471254010

OCLC:

62344031

Publisher Number:

9780471254010

Online:

Publisher description