Immunology / [edited by] David Male ... [and others].

Format:

Book

Contributor:

Male, David K., 1954-

Language:

English

Subjects (All):

Immunology.

Clinical immunology.

Immune System.

Immunity.

Medical Subjects:

Immune System.

Immunity.

Physical Description:

x, 552 pages : illustrations (mostly color) ; 28 cm

Edition:

Seventh edition.

Place of Publication:

Philadelphia, PA : Mosby Elsevier, 2006.

Summary:

Extensively updated, with new contributors, brilliant new illustrations and a wealth of supporting material online, this 7th edition offers you a carefully structured approach to learning the building blocks of the immune system and understanding how immune responses develop. It integrates the mechanisms of innate and adaptive immunity, and gives a clear description of the scientific principles of clinical immunology, integrated with histology, pathology, and clinical examples.

The website which accompanies this text gives access to all the text and images in the book, 16 detailed animations, a series of case studies and a test bank of case-based questions, to aid learning and enhance your understanding of the subject.

Contents:

Section 1 Components of the Immune System

1 Introduction to the immune system / David Male 3

2 Cells, tissues and organs of the immune system / Peter Lydyard, Carlo E Grossi 19

3 Antibodies / Roy Jefferis 59

4 Complement / B Paul Morgan 87

5 T cell receptors and MHC molecules / David B Roth 105

Section 2 Modes of Immune Response

6 Mechanisms of innate immunity / David Male 127

7 Antigen presentation / John Trowsdale 145

8 Cell Cooperation in the antibody response / Joseph C Marini 163

9 Mononuclear phagocytes in immune defence / Siamon Gordon 181

10 Cell mediated cytotoxicity / Gillian M Griffiths 203

11 Regulation of the immune response / Arne Akbar, Joanne E Cook 215

12 Immune responses in tissues / David Male 235

Section 3 Defence Against Infectious Agents

13 Immunity to viruses / Anthony A Nash 247

14 Immunity to bacteria and fungi / Gregory J Bancroft 257

15 Immunity to protozoa and worms / Janette E Bradley, Richard Pleass 277

16 Primary immunodeficiency / Fred S Rosen 299

17 AIDS and secondary immunodeficiency / Bruce D Walker 311

18 Vaccination / Peter C L Beverley 325

Section 4 Immune Responses Against Tissues

19 Immunological tolerance / D C Wraith 343

20 Autoimmunity and autoimmune disease / Ivan Roitt 365

21 Transplantation and rejection / Robert Lechler, Andrew J T George 383

22 Immunity to Cancers / P K Srivastava 401

Section 5 Hypersensitivity

23 Immediate hypersensitivity (Type I) / Thomas A E Platts-Mills 423

24 Hypersensitivity (Type II) / David Male 449

25 Hypersensitivity (Type III) / Frank Hay, Olwyn M R Westwood 461

26 Type IV hypersensitivity / Warwick Britton 477

Explanations for critical thinking and case studies 493

1 Major histocompatibility complex 507

2 Recognized CD markers of hemopoietic cells and their distribution 508

3 The major cytokines 522

4 Human chemokines and their receptors 524.

Notes:

Rev. ed. of Immunology / edited by Ivan Roitt, Jonathan Brostoff, David Male, 2001.

Includes bibliographical references and index.

ISBN:

0323033997

OCLC:

63396821

Publisher Number:

9780323033992