The early course of schizophrenia / edited by Tonmoy Sharma and Philip D. Harvey.

Format:

Book

Contributor:

Sharma, Tonmoy.

Harvey, Philip D., 1956-

Language:

English

Subjects (All):

Schizophrenia.

Schizophrenia--Susceptibility.

Schizophrenia--Treatment.

Schizophrenia--etiology.

Schizophrenia--therapy.

Medical Subjects:

Schizophrenia--etiology.

Schizophrenia--therapy.

Physical Description:

vi, 263 pages : illustrations ; 24 cm

Place of Publication:

Oxford ; New York : Oxford University Press, 2006.

Summary:

New developments in the basic and clinical neurosciences have led to important advances in our understanding of the events that occur between conception and birth that can influence schizophrenia. At the other end of the lifespan, some of the most exciting developments in years have recently been coming out of comprehensive studies of post-mortem studies of patients with schizophrenia. In the clinical domain, studies of first episode patients with schizophrenia are proliferating, at the same time as many research groups are performing comprehensive studies of patients with schizophrenia who are in the eighth decade of life or even older. Thus, many of the exciting new developments in research on schizophrenia are at the ends of the lifespan, suggesting that a wide-ranging treatment of schizophrenia in this framework will be very well accepted.

The Early Course of Schizophrenia is unique in adopting a lifespan approach to understanding schizophrenia. There are many aspects of schizophrenia that require research attention from a lifespan perspective. For example, there may be aspects of the behaviour or biological functioning that are present before the illness that change an individual's risk for developing the illness. There may be environmental events that can cause schizophrenia in the absence of other predisposing factors. There may be genetic influences on the development of schizophrenia that are modified by environmental events, either psychological or physiological. Factors such as an individual's gender or intelligence may also influence schizophrenia, either in terms of changing the risk for development or changing aspects of the illness' presentation, such as onset age or overall functional outcome.

With contributions from leading scientists in this field, and results from the frontiers of schizophrenia research, this volume is a major new addition to the psychiatry literature.

Contents:

Section 1 Schizophrenia in the premorbid period

1 Prenatal events that influence schizophrenia / Ezra Susser, Mark G. Opler 3

2 Interactions of genetic predisposition and intrauterine events in the etiology of schizophrenia / Lauren M. Ellman, Tyrone D. Cannon 19

3 Cognitive functioning before or at the onset of the first episode / Abraham Reichenburg, Michael Davidson 41

Section 2 Schizophrenia at the time of the first episode

4 Early onset schizophrenia: cognitive and clinical characteristics / Sophia Frangou 59

5 Brain imaging studies in childhood-onset schizophrenia / Nitin Gogtay, Judith L. Rapoport 71

6 Neurocognitive deficits and first-episode schizophrenia: characterization and course / Irene M. Bratti, Robert M. Bilder 87

7 Structural and functional brain abnormalities in first-episode schizophrenia / Tonmoy Sharma, Veena Kumari 111

8 Diagnostic variability in the early course of schizophrenia / Evelyn J. Bromet, Bushra Naz 131

9 Sex differences in schizophrenia: the case for developmental origins and etiological implications / Jill M. Goldstein, Deborah J. Walder 147

10 Late-onset schizophrenia: characteristics of patients at the first episode / Philip D. Harvey 175

Section 3 Treatment of early schizophrenia

11 Prodromal period: pharmacological and behavioural interventions / Alison R. Yung, Lisa J. Phillips, Patrick D. McGorry 189

12 Treatment of schizophrenia at the first episode / Delbert G. Robinson 211

13 Treatment of late-onset schizophrenia / Gauri V. Nayak, David P. Folsom, Elizabeth W. Twamley, Dilip V. Jeste 225

14 Treatment of cognitive deficits in first episode psychosis / Richard S. E. Keefe, Joseph W. Kang 237.

Notes:

Includes bibliographical references and index.

ISBN:

0198510845

0198568959

OCLC:

60838586

Publisher Number:

9780198510840

9780198568957