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Molecular genetic testing in surgical pathology / [edited by] John D. Pfeifer ; with contributions by Daniel A. Arber ... [and others].
Veterinary: Atwood Library (Campus) RD57 .M595 2006
Available
LIBRA Oversize RD57 .M595 2006
Available from offsite location
- Format:
- Book
- Language:
- English
- Subjects (All):
- Pathology, Surgical--Technique.
- Pathology, Surgical.
- Human molecular genetics.
- Tumors--Genetic aspects.
- Tumors.
- Neoplasms--pathology.
- Molecular Diagnostic Techniques--methods.
- Neoplasms--genetics.
- Medical Subjects:
- Neoplasms--pathology.
- Pathology, Surgical.
- Molecular Diagnostic Techniques--methods.
- Neoplasms--genetics.
- Physical Description:
- 474 pages, 16 unnumbered pages of plates : illustrations (some color) ; 29 cm
- Place of Publication:
- Philadelphia : Lippincott, Williams & Wilkins, [2006]
- Summary:
- Written by experts from Washington University School of Medicine, this text is a thorough review of the specific molecular genetic techniques that can provide diagnostically useful molecular genetic information on tissue samples--including cytogenetics, fluorescence in situ hybridization (FISH), PCR, electrophoresis and hybridization analysis, DNA sequence analysis, and microarrays. The first part of the book describes each technique, indicates its advantages, disadvantages, capabilities, and limitations, and systematically addresses sensitivity and specificity issues. Subsequent chapters, organized by organ system, detail the specific applications of these tests in diagnostic surgical pathology. More than 200 full-color and black-and-white illustrations complement the text.
- Contents:
- Structure and function of DNA and RNA
- DNA damage, mutations, and repair
- Cytogenetics
- Fluorescence in situ hybridization / Arie Perry
- Polymerase chain reaction
- Nucleic acid electrophoresis and hybridization
- DNA sequence analysis
- Sensitivity and specificity issues
- Microarrays / Mark A. Watson
- Clinical testing of patient's specimens / Barbara A. Zehnbauer
- Tumors of soft tissue and bone
- Endocrine system
- Molecular diagnostics in hematopathology / M. Rajan Mariappan and Daniel A. Arber
- Neural tumors and neuromuscular diseases / Pang-hsien Tu, Christine E. Fuller, and Arie Perry
- Gastrointestinal tract
- Reproductive organs
- Urinary tract
- Skin
- Lung and mediastinum
- Breast
- Head and neck
- Infectious diseases
- Identity determination
- The future.
- Notes:
- Includes bibliographical references and index.
- ISBN:
- 0781747481
- OCLC:
- 61704740
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