Principles of toxicology / Karen E. Stine, Thomas M. Brown.

Format:

Book

Author/Creator:

Stine, Karen E.

Contributor:

Brown, Thomas M. (Thomas Miller)

Language:

English

Subjects (All):

Toxicology.

Medical Subjects:

Toxicology.

Physical Description:

374 pages : illustrations ; 25 cm

Edition:

Second edition.

Place of Publication:

Boca Raton : CRC Taylor & Francis, 2006.

Summary:

Written by two experienced toxicology lecturers, Principles of Toxicology provides a broad-based yet comprehensive introduction to this diverse subject. Easy-to-read and comprehensive, the book covers this broad and interdisciplinary field from the viewpoint of three different functional levels: molecular and cellular; physiological; and ecological and environmental. This revised second edition expands the diversity of the book while keeping the organizational format that made the first edition a bestseller. It also includes a series of brief case studies illustrating the application of principles to current issues of interest.

See what's new in the second edition: Material in the areas of comparative toxicology and the role of biotransformation in human disease, Coverage of the role of genomics in toxicology, Advances in understanding of carcinogenesis, particularly roles of oncogenes and tumor suppressor genes, New understanding of excitotoxicology and the potential role of toxicants in neurological disease, New chapter on the role of toxicology in pharmacology, focusing on drug development, New chapter on the role of toxicology in forensic investigations.

Each and every chapter has been revised, several significantly updated, and three are entirely new. The book contains an extensive cross-referencing system that links all sections and enhances the integration of material. It includes an appendix of selected toxicants that describes chemical structure and category of use. These features combine to make finding specific information quick and easy. The highly readable format provides a uniform, consistent presentation of information.

Contents:

Measuring toxicity and assessing risk

Toxicokinetics

Biotransformation

Cellular sites of action

Genomics and new genetics in toxicology

Carcinogenesis

Reproductive toxicology and teratology

Respiratory toxicology

Cardiovascular toxicology

Neurotoxicology

Hepatic toxicology

Renal toxicology

Immunotoxicology

Ecological toxicology

Applications: pharmacology and toxicology

Applications: forensic toxicology

Applications: environmental toxicology and pollution.

Notes:

Includes bibliographical references and index.

ISBN:

084932856X

OCLC:

61459352

Publisher Number:

9780849328565