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Gene-environment interactions : fundamentals of ecogenetics / edited by Lucio G. Costa and David L. Eaton.

Holman Biotech Commons QH456 .G46 2006
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Veterinary: Atwood Library (Campus) QH456 .G46 2006
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Format:
Book
Contributor:
Costa, Lucio (Lucio G.)
Eaton, David L.
Language:
English
Subjects (All):
Ecological genetics.
Environmentally induced diseases--Genetic aspects.
Environmentally induced diseases.
Genetic toxicology.
Disease susceptibility--Genetic aspects.
Disease susceptibility.
Human genetics--Variation.
Human genetics.
Ecology.
Disease Susceptibility.
Disorders of Environmental Origin.
Medical Subjects:
Ecology.
Disease Susceptibility.
Disorders of Environmental Origin.
Physical Description:
xv, 557 pages : illustrations ; 23 cm
Place of Publication:
Hoboken, N.J. : Wiley-Liss, 2006.
Summary:
Understanding the play between heredity and environment, and relating it to disease causation, is the task of ecogenetics. Gene-Environment Interactions: Fundamentals of Ecogenetics presents the first comprehensive survey of this discipline, reflecting its relationship with toxicology, epidemiology, pharmacology, public health, and other medical and biological fields.
Packed with clear examples illustrating concepts, as well as numerous tables and figures, Gene-Environment Interactions: Fundamentals of Ecogenetics is a unique resource for a wide range of physicians, students, and other specialists.
Contents:
Chapter 2 Ecogenetics: Historical Perspectives / Gilbert S. Omenn, Arno G. Motulsky 7
Chapter 3 Tools of Ecogenetics / Theo K. Bammler, Federico M. Farin, Richard P. Beyer 17
Chapter 4 Epidemiologic Approaches / Harvey Checkoway, Parveen Bhatti, Anneclaire De Roos 51
Chapter 5 Statistical Issues in Ecogenetic Studies / Stephanie A. Monks 73
Chapter 6 Overview of Section II / Lucio G. Costa, David L. Eaton 91
Chapter 7 Polymorphisms in Cytochrome P450 and Flavin- Containing Monooxygenase Genes / Catherine K. Yeung, Allan E. Rettie, Kenneth E. Thummel 95
Chapter 8 Polymorphisms in Xenobiotic Conjugation / Helen E. Smith, David L. Eaton, Theo K. Bammler 127
Chapter 9 Paraoxonase, Butyrylcholinesterase, and Epoxide Hydrolase / Lucio G. Costa, Toby B. Cole, Gary K. Geiss, Clement E. Furlong 159
Chapter 10 DNA Repair Enzymes / Jon P. Anderson, Lawrence A. Loeb 179
Chapter 11 Receptors and Ion Channels / Lucio G. Costa 197
Chapter 12 Overview of Section III / Lucio G. Costa, David L. Eaton 213
Chapter 13 Lung Cancer / Valle Nazar-Stewart 215
Chapter 14 Gastrointestinal Cancers / Thomas L. Vaughan 239
Chapter 15 Neurodegenerative Diseases / Samir N. Kelada, Harvey Checkoway, Lucio G. Costa 253
Chapter 16 Cardiovascular Disease / Melissa A. Austin, Stephen M. Schwartz 271
Chapter 17 Type 2 Diabetes / Karen L. Edwards 285
Chapter 18 Infectious Disease Ecogenetics / David R. Sherman 303
Chapter 19 Genetic Variation, Diet, and Disease Susceptibility / Johanna W. Lampe, John D. Potter 321
Chapter 20 Genetic Determinants of Addiction to Alcohol, Tobacco, and Drugs of Abuse / Andrew J. Saxon 351
Chapter 21 Overview of Section IV / Lucio G. Costa, David L. Eaton 377
Chapter 22 Ethical Issues in Ecogenetics / Kelly Fryer-Edwards, Lindsay A. Hampson, Christopher R. Carlsten, Wylie Burke 381
Chapter 23 Social and Psychological Aspects of Ecogenetics / Deborah Bowen, Shirley Beresford, Brenda Diergaarde 397
Chapter 24 Legal Issues / Kate Battuello, Anna Mastroianni 411
Chapter 25 Risk Assessment and the Impact of Ecogenetics / Elaine M. Faustman, Gilbert S. Omenn 427.
Notes:
Includes bibliographical references (pages 451-529) and index.
ISBN:
0471467812
OCLC:
61756961
Publisher Number:
9780471467816

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