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Genome instability in cancer development / edited by Erich A. Nigg.
Holman Biotech Commons R850.A1 A39 v.570 2005
Available
- Format:
- Book
- Series:
- Advances in experimental medicine and biology ; v. 570.
- Advances in experimental medicine and biology ; v. 570
- Language:
- English
- Subjects (All):
- Cancer--Genetic aspects.
- Cancer.
- Genomics.
- Neoplasms--genetics.
- Neoplasms--etiology.
- Genomic Instability.
- Mutation.
- DNA Repair.
- Medical Subjects:
- Neoplasms--genetics.
- Neoplasms--etiology.
- Genomic Instability.
- Mutation.
- DNA Repair.
- Physical Description:
- xv, 511 pages : illustrations (some color) ; 26 cm.
- Place of Publication:
- New York : Springer, [2005]
- Contents:
- The problem of genome instability. The multiplicity of mutations in human cancers / Ranga N. Venkatesan and Lawrence A. Loeb. Monitoring chromosome rearrangements / Michael R. Speicher
- DNA repair and mutagenesis. Nucleotide excision repair and its connection with cancer and ageing / Jaan-Olle Andressoo, Jan H.J. Hoeijmakers and Harm de Waard. DNA mismatch repair and colon cancer / Giancarlo Marra and Josef Jiricny. Base excision repair / Lisiane B. Meira, Nicholas E. Burgis and Leona D. Samson. Genomic instability in cancer development / Penny A. Jeggo. Translesion synthesis and error-prone polymerases / Catherine M. Green and Alan R. Lehmann
- Cell cycle progression and chromosome aberration. The INK4A/ARF network-cell cycle checkpoint or emergency brake? / Ana Gutierrez del Arroyo and Gordon Peters. DNA replication and genomic instability / Wenge Zhu, Tarek Abbas and Anindya Dutta. The dream of every chromosome: equal segregation for a healthy life of the host / Tomohiro Matsumoto and Mitsuhiro Yanagida. Telomere structural dynamics in genome integrity control and carcinogenesis / Roger A. Greenberg and K. Lenhard Rudolph. Gene amplification mechanisms / Michelle Debatisse and Bernard Malfoy. DNA methylation and cancer-associated genetic instability / Melanie Ehrlich. Deregulation of the centrosome cycle and the origin of chromosomal instability in cancer / Wilma L. Lingle, Kara Lukaswiewicz and Jeffrey L. Salisbury
- Genome integrity checkpoints. Mammalian DNA damage response pathway / Zhenkun Lou and Junjie Chen. ATM and cellular response to DNA damage / Martin F. Lavin ... [et al.] Mitotic checkpoint, aneuploidy and cancer / Tim J. Yen and Gary D. Kao.
- Notes:
- Includes bibliographical references and index.
- ISBN:
- 1402037635
- 1402037643
- OCLC:
- 63394908
- Publisher Number:
- 9781402037634
- 9781402037641
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