Extracranial stereotactic radiotherapy and radiosurgery / edited by Ben J. Slotman, Timothy D. Solberg, Dirk Verellen.

Format:

Book

Contributor:

Slotman, Ben J.

Solberg, Timothy.

Verellen, Dirk.

Language:

English

Subjects (All):

Cancer--Radiotherapy.

Cancer.

Stereotaxic techniques.

Head and Neck Neoplasms--radiotherapy.

Radiosurgery--methods.

Medical Subjects:

Head and Neck Neoplasms--radiotherapy.

Radiosurgery--methods.

Physical Description:

xi, 328 pages, 24 pages of plates : illustrations (some color) ; 24 cm

Place of Publication:

New York : Taylor & Francis, 2006.

Summary:

For radiation oncologists and physicists who want an authoritative overview of emerging developments in the field, as well as clear direction on the utilization of this new technology in clinical practice, this reference provides in-depth descriptions of new and promising stereotactic methods for the application of stereotactic radiotherapy for the treatment of extracranial tumors.

Illustrating the impact of stereotactic precision on the management of cancer, this guide covers the development of new technologies for tumor localization, target immobilization and tracking, dosimetry, and radiation delivery...the development of various approaches to deliver radiation to extracranial targets with stereotactic precision...and clinical results for various tumor sites.

Contents:

2 The ELEKTA Stereotactic Body Frame / Jorn Wulf 5

System Description 6

Accuracy of Patient and Target Reproducibility in the SBF 9

Treatment Planning and Delivery 13

3 Novalis / Paul Medin, Dirk Verellen 19

System Description 20

Patient Positioning 21

Verification and Clinical Validation 28

Treatment Planning and Treatment Delivery 36

Treatment Verification 40

Treatment of Moving Targets 57

Capabilities and Limitations of the Technique 64

4 Whole-Body Radiosurgery with the CyberKnife / Achim Schweikard, Hiroya Shiomi, Minaro Uchida, John R. Adler 71

System Overview 75

Inverse Planning 75

Respiration Tracking 78

Clinical Trials 84

5 Serial Tomotherapeutic Approaches to Stereotactic Body Radiation Therapy / Bill Salter, Martin Fuss 89

System Description and Operation 89

Patient Immobilization and Alignment 91

Treatment Planning 94

Treatment Verification 100

Treatment of Moving Targets 104

Logistics of the Method 106

6 Anatomical and Biological Imaging / Frank J. Lagerwaard, Suresh Senan 109

Appropriate Selection of Patients 110

General Principles of Target Definition 113

Generating Representative Planning CT Scans 114

Repeated Treatment Planning in Between Fractions 119

Site Specific Comments 120

Follow-Up Imaging 122

7 Radiobiological Considerations of Stereotactic Body Radiotherapy / Steve P. Lee, H. Rodney Withers, Jack F. Fowler 131

Introduction: Clinical Radiobiology as a Four-Dimensional Problem 131

Radiobiology Problem Along the Temporal Domain: Time, Dose, and Fractionation 133

From Temporal Problem to Spatial Consideration: The "Double-Trouble" Effect 146

Radiobiology Problem Along the Spatial Domain: The Volume Effect 148

Radiobiology Problem in Four-Dimensions 162

Specific Issues Regarding SRS and SRT 164

Note Added in Proof 169

8 Stereotactic Radiation Therapy of Liver Tumors / Klaus K. Herfarth, Martin Fuss 177

Incidence 178

The Role of Stereotactic Body Radiation Therapy in the Multi-Disciplinary Treatment Arsenal 179

Organ-Specific Difficulties 181

Doses and Clinical Outcome 183

Partial Liver-Radiation Using Stereotactic Setup 185

Ongoing Studies 189

9 Stereotactic Radiotherapy of Lung Tumors / Robert D. Timmerman, Jorn Wulf 197

Lung Metastases 202

Radiobiology 203

Radiation Tolerance of Pulmonary Tissues 207

Treatment Outcome 216

Local Control and Survival 220

10 Prostate Tumors / Raymond Miralbell, Meritxell Molla, Lluis Escude, Dirk Verellen, Guy Soete, Guy Storme 231

The TEKNON Experience 231

Hypofractionated Boost with Intensity Modulated X-Ray Beams Under Stereotactic Conditions: A Pilot Study 233

Final Comments and Conclusions 244

The AZ-VUB Experience 246

Treatment Protocol and Irradiation Technique 246

Clinical Follow-Up 248

11 ECSRT for Spinal Tumors / Samuel Ryu, Fang-Fang Yin 257

Introduction and Clinical Indications 257

Techniques for Spinal Radiosurgery 260

Clinical Applications and Outcomes 275

12 Stereotactic Radiotherapy of Head and Neck Tumors / Robert Smee, Reinhard Wurm 285

Technique and Indications 289

Incidence 308

Organ Site-Specific Difficulties 309

Fractionated Dose Selection 311

Treatment Delivery 313

Logistics 314

Future Use and Research 316.

Notes:

Includes bibliographical references and index.

ISBN:

0824726979

OCLC:

61351628

Publisher Number:

9780824726973