Gene therapy of autoimmune diseases / [edited by] Gérald J. Prud'homme.

Format:

Book

Contributor:

Prud'homme, Gérald J.

Series:

Medical intelligence unit (Unnumbered : 2003)

Medical intelligence unit

Language:

English

Subjects (All):

Autoimmune diseases--Gene therapy.

Autoimmune diseases.

Autoimmune Diseases--therapy.

Genetic Therapy--methods.

Gene Targeting.

Gene Transfer Techniques.

Genetic Vectors.

Vaccines, DNA.

Gene therapy.

Medical Subjects:

Autoimmune Diseases--therapy.

Genetic Therapy--methods.

Gene Targeting.

Gene Transfer Techniques.

Genetic Vectors.

Vaccines, DNA.

Physical Description:

138 pages : illustrations ; 24 cm.

Place of Publication:

Georgetown, Tex. : Landes Bioscience/Eurekah.com ; New York, N.Y. : Kluwer Academic/Plenum Publishers, [2005]

Summary:

Autoimmune diseases are diverse and responsible for considerable morbidity. Their etiology remains largely unknown, and current therapy with anti-inflammatory drugs is prone to adverse effects, and rarely curative. New therapies with anti-cytokine antibodies or receptors are promising, but require frequent administration of expensive protein drugs. Gene Therapy of Autoimmune Diseases comprehensively reviews research in gene therapy for autoimmune diseases with viral or non-viral vectors. Gene therapy offers the possibility of long-term, continuous delivery of a wide variety of immunosuppressive, anti-inflammatory, or tolerance-inducing agents. Moreover, highly specific genetically modified cells can be produced. This book discusses the most promising avenues in this exciting new field.

Contents:

Gene therapy approaches for autoimmune diseases of the central nervous system and other tissues / Roberto Furlan ... [et al.]

Gene therapeutics in autoimmune diabetes / Jon D. Piganelli, Massimo Trucco, and Nick Giannoukakis

Immunogene therapy with nonviral vectors / Ciriaco A. Piccirillo, Argyrios N. Theofilopoulos, and Gérald J. Prud'homme

Targeting antigen-specific T cells for gene therapy of autoimmune disease / Justin M. Johnson and Vincent K. Tuohy

Therapeutic gene transfer for rheumatoid arthritis / Natacha Bessis and Marie-Christophe Boissier

Gene therapy-based approach for immune tolerance induction using recombinant immunoglobulin carriers / Moustapha El-Amine ... [et al.]

DNA vaccination against autoimmune diseases / Gérald J. Prud'homme ... [et al.].

Notes:

Includes bibliographical references and index.

ISBN:

0306479915

OCLC:

57731381