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Antiviral agents, vaccines, and immunotherapies / Stephen K. Tyring.
Levy Dental Medicine Library - Stacks RM411 .T974 2005
Available
LIBRA RM411 .T974 2005
Available from offsite location
- Format:
- Book
- Author/Creator:
- Tyring, Stephen K. (Stephen Keith)
- Series:
- Infectious disease and therapy ; v. 34.
- [Infectious disease and therapy ; v. 34]
- Language:
- English
- Subjects (All):
- Antiviral agents.
- Immunotherapy.
- Antiviral Agents.
- Vaccines.
- Immunotherapy, Active.
- Virus Diseases--therapy.
- Virus Diseases--prevention & control.
- Medical Subjects:
- Antiviral Agents.
- Vaccines.
- Immunotherapy.
- Immunotherapy, Active.
- Virus Diseases--therapy.
- Virus Diseases--prevention & control.
- Physical Description:
- xii, 424 pages : illustrations ; 24 cm.
- Place of Publication:
- New York : Marcel Dekker, 2005.
- Summary:
- Unlike any other source on the subject, this reference analyzes the benefits and limitations of every available drug, vaccine, and immunotherapy utilized in the prevention and control of viral diseases-providing in-depth reviews of more than fifty drugs and antiviral agents for HIV, human herpesviruses, human papillomaviruses (HPV), influenza, respiratory syncytial virus, hepatitis B, and hepatitis C-analyzing their mechanisms of action, dosage, side effects, and drug resistance. Keeping abreast of recent advances in the field, this guide examines the background of antiviral agent and vaccine development and focuses on future demands for both recognized and emerging viral diseases...analyzes the benefits of vaccines, the economics of vaccine development, and difficulties associated with vaccine production...covers the use and limitations of passive immunity...provides an overview of the use of immunoglobulins and monoclonal antibodies for antiviral therapy...and supplies extensive references, tables, and figures throughout the text.
- Contents:
- Chapter 2 Antiretroviral Drugs to Treat Human Immunodeficiency Virus Infections 25
- Human Immunodeficiency Virus 27
- Nucleoside Reverse Transcriptase Inhibitors 39
- Zidovudine [AZT] (Retrovir) 39
- Didanosine [ddI] (Videx) 42
- Stavudine [d4T] (Zerit) 44
- Zalcitabine [ddc] (Hivid) 46
- Lamivudine [3TC] (Epivir) 48
- Abacavir [ABC] (Ziagen) 50
- Emtricitabine (Emtriva, Coviracil, FTC) 52
- Non-Nucleoside Reverse Transcriptase Inhibitors 53
- Nevirapine [NVP] (Viramune) 54
- Delavirdine [DLV] (Rescriptor) 56
- Efavirenz [EFV] (Sustiva) 59
- Nucleotide Reverse Transcriptase Inhibitors 62
- Tenofovir Disproxil Fumerate (Viread) 62
- HIV Protease Inhibitors 65
- Saquinavir [SQV] (Invirase: Hard Gel; Fortovase: Soft Gel) 67
- Ritonavir [RTV] (Norvir) 68
- Indinavir [IDV] (Crixivan) 71
- Nelfinavir [NFV] (Viracept) 75
- Amprenavir [APV] (Agenerase) 77
- Fosamprenavir (Lexiva, GW 433908) 80
- Atazanavir (Reyataz, BMS-232632) 83
- Lopinavir + Ritonavir [ABT-378/r] (Kaletra) 84
- Fusion Inhibitors 85
- Enfuvirtide (ENF, T-20, Pentasufide, Fuzeon) 86
- Investigational Drugs 88
- Chapter 3 General (Non-Antiretroviral) Antiviral Drugs 123
- Viral Infections Other than HIV 126
- Herpes Simplex Virus (HSV-1 and -2) 126
- Varicella Zoster Virus (VZV) 131
- Epstein-Barr Virus (EBV) 132
- Cytomegalovirus (CMV) 133
- Human Herpesvirus 8 (HHV-8) 135
- Human Papillomavirus (HPV) 135
- Molluscum Contagiosum Virus (MCV) and other Poxviruses 137
- Hepatitus B Virus (HBV)/Hepatitus C Virus (HCV) 139
- Influenza Virus 140
- Respiratory Syncytial Virus (RSV) 142
- Rhinovirus 142
- Nucleoside Analogs 143
- Acyclovir 143
- Valacyclovir 154
- Famciclovir 160
- Penciclovir 166
- Ganciclovir 169
- Valganciclovir 174
- Ribavirin 178
- Nucleotide Analogs 184
- Cidofovir 184
- Adefovir 190
- Antisense Drugs 195
- Fomivirsen 196
- Topical Immune Modulators 199
- Imiquimod 199
- Interferon-Alpha and Combinations 204
- Interferon-Alpha 205
- PEG-Interferon 210
- Ribavirin and Interferon-Alpha 213
- Ion Channel Function Inhibitors of M2 Proteins and Neuraminidase Inhibitors 216
- Amantadine 217
- Rimantadine 224
- Zanamivir 226
- Oseltamivir 230
- Pyrimidines 235
- Trifluridine (1% Ophthalmic Solution) 235
- Other Antivirals and Medications 238
- Foscarnet 238
- Docosonal 245
- Implications for New Antiviral Agents 246
- Chapter 4 Vaccines and Immunotherapies 291
- Smallpox and Other Poxviruses 296
- New Vaccines for Poxviruses Currently Under Investigation 300
- Measles, Mumps, and Rubella Vaccines 300
- Varicella-Zoster Virus Vaccine 315
- Influenza Virus Vaccine 318
- New Developments in Influenza Vaccines 321
- Hepatitis A Virus Vaccine 321
- Hepatitis B Virus Vaccine 323
- Rabies Virus Vaccine 326
- Recent and Continuing Developments in Rabies Vaccines 330
- Poliovirus Vaccines 331
- Yellow Fever Virus Vaccine 336
- Japanese Encephalitis Virus Vaccine 339
- Adenovirus Vaccines 341
- Investigational Vaccines 342
- Rotavirus 342
- Varicella-Zoster Virus Vaccine 345
- Human Immunodeficiency Virus Vaccine 349
- Herpes Simplex Virus Vaccine 352
- Human Papillomavirus Vaccine 354
- Cytomegalovirus Vaccine 355
- Respiratory Syncytial Virus Vaccine 357
- Parainfluenza Virus Vaccine 359
- Other Vaccines 361
- Immunoglobulins 362
- Monoclonal Antibodies 367.
- Notes:
- Series information obtained from Dekker website.
- Includes bibliographical references and index.
- ISBN:
- 0824754085
- OCLC:
- 58604581
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