Structural biology of bacterial pathogenesis / edited by Gabriel Waksman, Michael Caparon, Scott Hultgren.

Format:

Book

Contributor:

Waksman, Gabriel.

Caparon, Michael.

Hultgren, Scott.

Language:

English

Subjects (All):

Virulence (Microbiology).

Bacteria--Ultrastructure.

Bacteria.

Molecular microbiology.

Bacteria--pathogenicity.

Bacterial Infections--microbiology.

Bacterial Physiological Phenomena.

Virulence Factors.

Medical Subjects:

Bacteria--pathogenicity.

Bacterial Infections--microbiology.

Bacterial Physiological Phenomena.

Virulence Factors.

Physical Description:

xi, 273 pages, 40 unnumbered pages of plates : illustrations (some color) ; 26 cm

Place of Publication:

Washington, D.C. : ASM Press, [2005]

Summary:

Written by experts in the field, Colonization of Mucosal Surfaces is an in-depth examination of the complex ecosystems of the mammalian mucosa and the successful adaptations of microorganisms that enable them to effectively colonize these surfaces. First addressing general considerations, this interesting new volume comprehensively covers colonization of the respiratory tract, the gastrointestinal tract, and the genitourinary tract, probing the various organisms present at these surfaces. Aspects of bacterial colonization revealed by the most recent research are discussed, including penetration of the mucous layer, innate immune effectors and their subversion, signaling of host cells by adherence factors, modulation of adherence, phase variation of colonization factors, and regulation of colonization effectors.

This new text offers a comprehensive, up-to-date account of those structural classes of antibiotics that have had an impact in human infectious disease. While most of the attention is on natural products with antibiotic activity elaborated by microbes to act as chemical weapons on neighboring bacteria, synthetic chemicals with antibiotic activity are also discussed.

The Enterococci offers a comprehensive primary text on enterococci and covers pathogenesis, molecular biology, and antibiotic resistance. This volume will be of great value to those dealing with the consequences of antibiotic-resistant infection, those actively engaged in enterococcal research, and those searching for a scientific basis for public policy decisions.

Contents:

Regulation of transcription by anti-sigma factors / Elizabeth A. Campbell and Seth A. Darst

Two-component signal transduction and chemotaxis / Jodi B. Lubetsky and Ann M. Stock

Sugar recognition and bacterial attachment / Craig L. Smith ... [et al.]

Host receptors of bacterial origin / Calvin K. Yip, Cecilia P.C. Chiu, and Natalie C.J. Strynadka

The chaperone-usher pathway of pilus fiber biogenesis / Frederic G. Sauer, Scott J. Hultgren, and Gabriel Waksman

Structure and assembly of type IV pilins / Katrina T. Forest

Sortase pathways in gram-positive bacteria / Kevin M. Connolly and Robert T. Clubb

Structural determinants of Haemophilus influenzae adherence to host epithelia: variations on type V secretion / Neeraj K. Surana ... [et al.]

Type III secretion machinery and effectors / C. Erec Stebbins

Type IV secretion machinery / Gunnar Schröder ... [et al.]

Injectosomes in gram-positive bacteria / Rodney K. Tweten and Michael Caparon

Toll/interleukin-1 receptors and innate immunity / Liang Tong.

Notes:

Includes bibliographical references and index.

ISBN:

1555813011

OCLC:

57316748