Polymeric gene delivery : principles and applications / edited by Mansoor M. Amiji.

Format:

Book

Contributor:

Amiji, Mansoor M.

Language:

English

Subjects (All):

Gene therapy.

Polymeric drug delivery systems.

Genetic Therapy--methods.

Genetic Vectors.

Polymers.

Medical Subjects:

Genetic Therapy--methods.

Genetic Vectors.

Polymers.

Physical Description:

686 pages, 4 unnumbered pages of plates : illustrations (some color) ; 26 cm

Place of Publication:

Boca Raton : CRC Press, [2005]

Contents:

Part I Gene Delivery: Challenges and Opportunities

Chapter 2 Tissue- and Cell-Specific Targeting for the Delivery of Genetic Information / Randall J. Mrsny 5

Chapter 3 Biological Barriers to Gene Transfer / Yasufumi Kaneda 29

Chapter 4 Cellular Uptake and Trafficking / Sujatha Dokka, Yon Rojanasakul 43

Chapter 5 Pharmacokinetics of Polymer-Plasmid DNA Complex / Makiya Nishikawa, Yoshinobu Takakura, Mitsuru Hashida 63

Part II Condensing Polymeric Systems

A Non-Degradable Polymers

Chapter 6 Poly(L-Lysine) and Copolymers for Gene Delivery / Minhyung Lee, Sung Wan Kim 79

Chapter 7 Gene Delivery Using Polyethylenimine and Copolymers / Manfred Ogris 97

Chapter 8 Poly(2-(dimethylamino)ethyl methacrylate)-Based Polymers for the Delivery of Genes In Vitro and In Vivo / F.J. Verbaan, D.J.A. Crommelin, W.E. Hennink, G. Storm 107

Chapter 9 Cationic Dendrimers as Gene Transfection Vectors: Dendri-Poly(amidoamines) and Dendri-Poly(propylenimines) / Lori A. Kubasiak, Donald A. Tomalia 133

Chapter 10 Poly(ethylene glycol)-Conjugated Cationic Dendrimers / Joon Sig Choi, Tae-il Kim, Jong-Sang Park 159

Chapter 11 Water-Soluble Lipopolymers for Gene Delivery / Ram I. Mahato, Sung Wan Kim 175

Chapter 12 Cyclodextrin-Containing Polymers for Gene Delivery / Suzie H. Pun, Mark E. Davis 187

B Biodegradable Polymers

Chapter 13 Gene Delivery Using Polyimidazoles and Related Polymers / Sharon Wong, David Putnam 213

Chapter 14 Degradable Poly([beta]-amino ester)s for Gene Delivery / David M. Lynn, Daniel G. Anderson, Akin Akinc, Robert Langer 227

Chapter 15 Cationic Polyesters as Biodegradable Polymeric Gene Delivery Carriers / Yong-Beom Lim, Yan Lee, Jong-Sang Park 243

Chapter 16 Poly(amidoamine)s for Gene Delivery / Paolo Ferruti, Jacopo Franchini 255

Chapter 17 Cationic Polysaccharides for Gene Delivery / Tony Azzam, Abraham J. Domb 279

Chapter 18 Gene Delivery Using Chitosan and Chitosan Derivatives / Gerrit Borchard, Maytal Bivas-Benita 301

Part III Non-Condensing Polymeric Systems

Chapter 19 Pluronic Block Copolymers for Nonviral Gene Delivery / Alexander V. Kabanov, Srikanth Sriadibhatla, Valery Yu. Alakhov 313

Chapter 20 Use of Poly(N-vinyl pyrrolidone) with Noncondensed Plasmid DNA Formulations for Gene Therapy and Vaccines / Michael Nicolaou, Polly Chang, Mark J. Newman 329

Chapter 21 Use of HPMA Copolymers in Gene Delivery / David Oupicky 345

Part IV Polymeric Nanospheres and Microspheres

A Polymeric Nanospheres

Chapter 22 Biodegradable Nanoparticles as a Gene Expression Vector / Swayam Prabha, Wenxue Ma, Vinod Labhasetwar 357

Chapter 23 Nanoparticles Made of Poly(lactic acid) and Poly(ethylene oxide) as Carriers of Plasmid DNA / Noemi Csaba, Celso Perez, Alejandro Sanchez, Maria Jose Alonso 367

Chapter 24 Poly(alkylcyanoacrylate) Nanoparticles for Nucleic Acid Delivery / Elias Fattal, Patrick Couvreur 387

Chapter 25 Layer-by-Layer Nanoengineering with Polyelectrolytes for Delivery of Bioactive Materials / Dinesh Shenoy, Alexei Antipov, Gleb Sukhorukov 399

Chapter 26 Ex Vivo and In Vivo Adenovirus-Mediated Gene Delivery into Refractory Cells via Nanoparticle Hydrogel Formulation / Ales Prokop, Gianluca Carlesso, Jeffrey M. Davidson 417

Chapter 27 Protein Nanoparticles for Gene Delivery / Goldie Kaul, Mansoor Amiji 429

B Polymeric Microspheres

Chapter 28 Gene Delivery Using Poly(lactide-co-glycolide) Microspheres / Mary Lynne Hedley 451

Chapter 29 Polyanhydride Microspheres for Gene Delivery / Yong S. Jong, Camilla A. Santos, Edith Mathiowitz 467

Chapter 30 Microspheres Formulated from Native Hyaluronan for Applications in Gene Therapy / Yang H. Yun, Weiliam Chen 475

Part V Specialized Delivery Systems

Chapter 31 Genetically Engineered Protein-Based Polymers: Potential in Gene Delivery / Zaki Megeed, Hamidreza Ghandehari 489

Chapter 32 Glycopolymer Tools for Studying Targeted Nonviral Gene Delivery / Kevin G. Rice, Je-Seon Kim, Dijie Liu 509

Chapter 33 Targeted Gene Delivery via the Folate Receptor / Shih-Jiuan Chiu, Robert J. Lee 523

Chapter 34 Transferrin Receptor-Targeted Gene Delivery Systems / Ralf Kircheis, Ernst Wagner 537

Chapter 35 Gene Delivery to the Lungs / Berma M. Kinsey, Charles L. Densmore, Frank M. Orson 557

Chapter 36 Cutaneous Gene Delivery / James C. Birchall 573

Chapter 37 Enhancement of Wound Repair by Sustained Gene Transfer via Hyaluronan Matrices / Angela Kim, Daniel M. Checkla, Don Wen, Philip Dehazya, Weiliam Chen 589

Chapter 38 Gene Delivery from Tissue Engineering Matrices / Zain Bengali, Christopher B. Rives, Lonnie D. Shea 611

Chapter 39 Gene Therapy Stents for In-Stent Restenosis / Ilia Fishbein, Itay Perlstein, Robert Levy 625

Chapter 40 Gene Delivery Using BioMEMS / Krishnendu Roy 659.

Notes:

Includes bibliographical references and index.

ISBN:

084931934X

OCLC:

55000613