Brain and spinal tumors of childhood / edited by David A. Walker ... [and others].

Format:

Book

Contributor:

Walker, David A., 1953-

Language:

English

Subjects (All):

Tumors in children.

Brain--Tumors.

Brain.

Spine--Tumors.

Spine.

Brain Neoplasms.

Child.

Spinal Neoplasms.

Medical Subjects:

Brain Neoplasms.

Child.

Spinal Neoplasms.

Physical Description:

xx, 531 pages, 8 unnumbered pages of plates : illustrations (some color), portraits ; 28 cm

Place of Publication:

London : Arnold ; New York, NY : Distributed in the U.S.A. by Oxford University Press, 2004.

Summary:

Children with brain and spinal tumors account for 20-25 per cent of childhood cancers. Until the early 1990s there had been little progress in the development of new treatments, and outcomes were not improving despite advances seen in other childhood cancers. During the past 10 years, however, there has been a dramatic increase in interest in the subject among pediatric specialists worldwide, and new multidisciplinary teams have become established. There are encouraging early signs of improvement in outcomes, and more are anticipated. The publication of this comprehensive, but practical, evidence-based review of brain and spinal tumors in children is therefore very timely. The content includes detailed coverage of the diagnosis, clinical management, aftercare and monitoring, and underlying biology of brain and spinal tumors in children. International in approach, it draws on the experience of the European Childhood Brain Tumour Committee, linked to the International Society of Paediatric Oncology, and various multi-center clinical trials to reflect the various approaches to management that have arisen around the world. Brain and Spinal Tumors of Childhood will be essential reading for pediatric oncologists, pediatric neurologists, pediatric neurosurgeons and general pediatricians, to be referred to often in the clinical setting, and an invaluable reference for neuro-oncologists, neuropathologists, neuroradiologists, basic scientists, nursing staff and rehabilitation specialists in health, social and educational services.

Contents:

2 Historical basis of neuro-oncology / Jonathan A. G. Punt, Giorgio Perilongo, Roger E. Taylor, Cliff Bailey, David A. Walker 5

Part II Epidemiology

3 Epidemiology / Charles A. Stiller, W. Archie Bleyer 35

4a Neuroembryology / Paul J. Scotting, Vanessa J. Appleby 50

4b Tumor biology / Michael A. Grotzer 67

5 Pathology and molecular classification / Felice Giangaspero, Otmar D. Wiestler 80

Part III Diagnosis and Treatment Planning

6 Clinical syndromes / Jonathan A. G. Punt 99

7 Diagnostic imaging / Timothy Jaspan, Paul D. Griffiths 107

8 Clinical trials / Richard Sposto 162

Part IV Treatment Techniques and Neurotoxicities

9 Neurosurgical techniques / Paul D. Chumas, Atul Tyagi 177

10 Radiotherapy techniques / Rolf D. Kortmann, Carolyn R. Freeman, Roger E. Taylor, Christine Abercrombie, Anne Ingle 188

11 Neuropsychological outcome / Maureen Dennis, Brenda J. Spiegler, Daria Riva, Daune L. MacGregor 213

12 Drug delivery / Susan M. Blaney, Stacey L. Berg, Alan V. Boddy 228

Part V Disease-Specific Multidisciplinary Management

13a Astrocytic tumors, low-grade: general considerations / Astrid K. Gnekow, Roger J. Packer, Rolf D. Kortmann 245

13b Astrocytic tumors, low-grade: treatment considerations by primary site and tumor dissemination / Astrid K. Gnekow, Roger J. Packer, Rolf D. Kortmann 259

14 Astrocytic tumors, high-grade / Johannes E. A. Wolff, Pascal Chastagner 277

15 Brainstem tumors / David A. Walker, Jonathan A. G. Punt, Michael Sokal 291

16 Embryonic tumors / Joachin Kuhl, Francois Doz, Roger E. Taylor 314

17 Ependymal tumors / Abhaya V. Kulkarni, Eric Bouffet, James M. Drake 331

18a Germ-cell tumors of the central nervous system / Gabriele Calaminus, Maria Luisa Garre 345

18b Germ-cell tumors: a commentary / Jonathan L. Finlay 357

19 Infant brain tumors / Antony Michalski, Maria Luisa Garre 359

20 Craniopharyngioma / Richard D. Hayward, Catherine DeVile, Michael Brada 370

21 Intradural spinal tumors / Harold L. Rekate, Trimurti D. Nadkarni, Astrid K. Gnekow, Roger J. Packer, Rolf D. Kortmann 387

22 Rare tumors / Richard Grundy, Conor Mallucci 397

23 Exploiting biology for therapeutic gain / Richard Gilbertson, Donald M. O'Rourke 417

Part VI Late Consequences and Supportive Care

24 Toxicity and late effects / Helen Spoudeas, Fenella J. Kirkham 433

25 Physical care, rehabilitation, and complementary therapies / Carlos de Sousa, Lindy May, Virginia McGivern 463

26 Cognitive development and educational rehabilitation / Ronald C. Savage, Bradford J. Ross, Sue Walker, Beth Wicks 480

27 Quality of survival / Colin Kennedy, Adam Glaser 493

28 Information needs for children and families / Mark L. Greenberg, Darren Hargrave, Jane Bond 501

29 Future challenges / David A. Walker, Giorgio Perilongo, Jonathan A. G. Punt, Roger E. Taylor 515.

Notes:

Includes bibliographical references and index.

ISBN:

0340762608

OCLC:

56653763