Neuroglia / edited by Helmut Kettenmann, Bruce R. Ransom.

Format:

Book

Contributor:

Kettenmann, Helmut.

Ransom, Bruce R.

Language:

English

Subjects (All):

Neuroglia.

Neuroglia--physiology.

Nervous System Diseases--physiopathology.

Medical Subjects:

Neuroglia--physiology.

Nervous System Diseases--physiopathology.

Physical Description:

xix, 601 pages : illustrations ; 29 cm

Edition:

Second edition.

Place of Publication:

Oxford ; New York : Oxford University Press, 2005.

Summary:

Neuroglia is the only comprehensive reference book on the basic biology and function of glial cells. This long-awaited second edition has been completely reorganized and rewritten to include the dramatic advances in this field since the first edition was published almost 10 years ago. The impact of the second edition will be greater than that of the first because the majority of neuroscientists now acknowledge that neuroglia are elemental to most, if not all, brain functions. The second edition covers the entire field of glial research from the basic molecular and cellular properties of these cells to their involvement in neurological diseases, including stroke, Alzheimer's disease, and multiple sclerosis. It includes new chapters on transmitter release by exocytosis from glia, glia derived stem cells, glia and synaptic transmission, glia and axon guidance, a completely new section on mechanisms of glial injury, and several new chapters on the roles of glia in different diseases. Neuroglia, Second Edition, provides a basic introduction to the whole range of glial topics and detailed information with critical assessment of the research literature. Neuroscience textbooks focus on the properties of neurons, whereas this book fills the information void about the brain's other cells. Neuroglia, Second Edition, is an essential reference source for both newcomers to this field and established investigators. Graduate students in neuroanatomy, neurochemistry, neurophysiology, and molecular neurobiology will find the book indispensable. It is also a vital companion for researchers in these fields as well as clinicians in neurology, neurosurgery, neuropathology, neuro-oncology, physiatry, and psychiatry.

Contents:

1. The Concept of Neuroglia: A Historical Perspective / Helmut Kettenmann, Bruce R. Ransom 1

Part I Properties of Neuroglial Cells

Morphology and Ultrastructure of Glial Cells

2. Astrocytes and Ependymal Glia / Andreas Reichenbach, Hartwig Wolburg 19

3. Structure and Function of Oligodendrocytes / Arthur M. Butt 36

4. Schwann Cells and Myelin / Rudolf Martini 48

5. Microglial Cells / Wolfgang J. Streit 60

Lineage

6. Lineages of Astrocytes and Oligodendrocytes / James E. Goldman 72

7. The Schwann Cell Lineage / Kristjan R. Jessen, Rhona Mirsky 85

8. The Role of Neurogenic Astroglial Cells in the Developing and Adult Central Nervous System / Stephen C. Noctor, Lidija Ivic, Veronica Martinez-Cerdeno, Arnold R. Kriegstein 101

Physiological and Biochemical Properties

9. Voltage-Activated Ion Channels in Glial Cells / Michelle L. Olsen, Harald W. Sontheimer 112

10. Receptors for Neurotransmitters and Hormones / Helmut Kettenmann, Christian Steinhauser 131

11. Cytokine and Chemokine Receptors and Signaling / Duane R. Wesemann, Etty N. Benveniste 146

12. Mechanisms of Solute Transport in Glia / Neville Brookes 163

13. Gap Junctions and Hemichannels / Bruce R. Ransom, Zu-Cheng Ye 177

14. Quantal Release of Transmitter: Not Only from Neurons but from Astrocytes as Well? / Andrea Volterra, Jacopo Meldolesi 190

15. Enzymes of Carbohydrate and Energy Metabolism / Bernd Hamprecht, Stephan Verleysdonk, Heinrich Wiesinger 202

16. Second Messenger Systems / Sean Murphy, Brian R. Pearce 216

17. Intracellular Calcium Control Mechanisms in Glia / Marisa Luisa Cotrina, Maiken Nedergaard 229

18. Cytoskeletal Proteins in Astroglia / Lawrence F. Eng, Yuen Ling Lee 240

Part II Functions of Neuroglial Cells

Myelin

19. Molecular Biology of Myelination / Anthony T. Campagnoni 253

20. Factors Controlling Myelin Formation / Lynn D. Hudson 264

21. Myelin Function and Saltatory Conduction / Stephen G. Waxman, Lakshmi Bangalore 273

Immune Function

22. Cytokine Production / Francesca Aloisi 285

23. Interaction of Glial Cells with Monocytes / Ingo Bechmann, Robert Nitsch 302

24. Antigen Processing, Presentation, and T Cell Interaction / Harald Neumann 314

Blood-Brain Barrier

25. The Role of Glia in the Formation and Function of the Blood-Brain Barrier / Hannelore Bauer, Hans-Christian Bauer, Reiner F. Haseloff, Ingolf E. Blasig 325

Influence on Neurons

26. Extracellular Potassium and pH: Homeostasis and Signaling / Jonathan A. Coles, Joachim W. Deitmer 334

27. Astrocyte Neurotransmitter Uptake / Raymond A. Swanson 346

28. Glia and Synaptic Transmission / Eric A. Newman 355

29. The Central Role of Astrocytes in Neuroenergetics / Luc Pellerin, Pierre J. Magistretti 367

30. Growth Factors for Neurons Provided by Macroglial Cells / Bernhard Reuss, Klaus Unsicker 377

Development

31. Radial Glial Cells: Scaffolding for Cortical Development and Evolution / Pasko Rakic 389

32. Axon Guidance / Andreas Faissner 405

Part III Disease and Neuroglial Cells

Mechanisms of Glial Injury

33. Astrocyte Injury / Christopher J. Feeney, Peter K. Stys 421

34. Oligodendrocyte and Schwann Cell Injury / Jennifer K. Ness, Mark P. Goldberg 430

35. Response of Microglia to Brain Injury / Kazuyuki Nakajima, Shinichi Kohsaka 443

Recovery of Neural Function

36. Axonal Regeneration in the Peripheral Nervous System of Mammals / Olawale A.R. Sulaiman, J. Gordon, Tessa Gordon 454

37. Axonal Regeneration in the Central Nervous System of Mammals / Isabel Klusman, Martin E. Schwab 467

38. Transplantation of Myelin-Forming Cells / William F. Blakemore, Robin J.M. Franklin 477

Diseases

39. Multiple Sclerosis / Jack Antel, Douglas Arnold 489

40. Human Immunodeficiency Virus Infection of the Central Nervous System / Elena Ryzhova, Dennis L. Kolson, Francisco Gonzalez-Scarano 501

41. Focal Cerebral Ischemia: The Multifaceted Role of Glial Cells / Ulrich Dirnagl, Josef Priller 511

42. Gliomas / Michael Weller 521

43. Neurological Mouse Mutants: A Molecular-Genetic Analysis of Myelin Proteins / Klaus-Armin Nave, Ueli Suter 532

44. Astrocytic Swelling in Neuropathology / Alexander A. Mongin, Harold K. Kimelberg 550

45. The Activation of Microglia as an Early Sign of Disease Progression in Alzheimer's Disease / Robert Veerhuis, Jeroen J.M. Hoozemans, Annachiara Cagnin, Piet Eikelenboom, Richard B. Banati 563

46. Peripheral Neuropathy and the Schwann Cell / Rita M. Cowell, James W. Russell 573

47. Reaction of Glial Cells in Infectious Disorders of the Central Nervous System / Martina Deckert, Dirk Schluter 586.

Notes:

Includes bibliographical references and index.

ISBN:

0195152220

OCLC:

54537735