Principles and practice of gynecologic oncology / [edited by] William J. Hoskins ... [and others].

Format:

Book

Contributor:

Hoskins, William J., 1940-

Louis A. Duhring Fund.

Language:

English

Subjects (All):

Generative organs, Female--Cancer.

Generative organs, Female.

Genital Neoplasms, Female.

Medical Subjects:

Genital Neoplasms, Female.

Physical Description:

xix, 1419 pages, 8 unnumbered pages of plates : illustrations (some color) ; 29 cm

Edition:

Fourth edition.

Other Title:

Gynecologic oncology

Place of Publication:

Philadelphia : Lippincott Williams & Wilkins, [2005]

Summary:

This updated Fourth Edition provides comprehensive coverage of the biology of gynecologic cancer, the therapeutic modalities available, and the diagnosis and treatment of site-specific malignancies. Because of the importance of multimodality treatment, the site-specific chapters are co-authored by a surgical oncologist, a medical oncologist, a radiation oncologist, and a pathologist. A significant portion of this edition focuses on monoclonal antibodies, vaccines, and gene directed therapies and how they can greatly improve treatment outcomes. A new chapter on end-of-life care is also included. Three distinguished new editors--Richard R. Barakat, MD, Maurie Markman, MD, and Marcus E. Randall, MD--now join the editorial team.

Contents:

Section I. Epidemiology of Gynecologic Cancers 1

1 Epidemiology of Gynecologic Cancers / Louise A. Brinton, James V. Lacey, Jr., Mark E. Sherman 3

2 Clinical Genetics of Gynecologic Cancer / Steven A. Narod 33

3 The Biology of Gynecologic Cancer / Kristin K. Zorn, Ginger J. Gardner, Michael J. Birrer 39

4 Tumor Angiogenesis and Metastasis: Biology and Clinical Experience / Edwin M. Posadas, Elise C. Kohn 73

5 Oncogenes and Tumor-Suppressor Genes / Jeff Boyd, Andrew Berchuck 93

6 Immunotherapy of Gynecologic Malignancies / David Z. Chang, Paul J. Sabatini, Chaitanya R. Divgi, Philip O. Livingston, Alan N. Houghton 123

7 Development and Identification of Tumor Markers / Karina Reynolds, Usha Menon, Ian Jacobs 157

8 Cancer Prevention Strategies / Paul F. Engstrom, Frank L. Meyskens 179

9 Clinical Trials Methodology and Biostatistics / Brian Bundy, Mark Brady 199

10 Diagnostic Imaging Techniques in Gynecologic Oncology / S.M. Ascher, C. Cooper, L. Scoutt, I. Imaoka, H. Hricak 223

Section II. Therapeutic Modalities and Related Subjects 267

11 Perioperative and Critical Care / James J. Burke, II, Janet L. Osborne, Christopher K. Senkowski 269

12 Surgical Principles in Gynecologic Oncology / Dennis S. Chi, Donald G. Gallup 311

13 Laparoscopic Surgery in Gynecologic Cancer / Daniel F. Dargent, Marie Plante, Yukio Sonoda 333

14 Biologic and Physical Aspects of Radiation Oncology / Carlos A. Perez, James A. Purdy, Zuofeng Li, E. J. Hall 375

15 Principles of Chemotherapy in Gynecologic Cancer / Michael A. Bookman 461

16 Pharmacology and Therapeutics in Gynecologic Cancer / David S. Alberts, Lisa M. Hess, Daniel D. Von Hoff, Robert T. Dorr 489

17 Hormones and Human Malignancies / Amir A. Jazaeri, G. Larry Maxwell, Laurel W. Rice 561

18 Innovative Twenty-first Century Therapies / Eric K. Rowinsky, Arno J. Mundt, Nadeem R. Abu-Rustum 587

Section III. Disease Sites 625

19 Pathogenesis and Diagnosis of Preinvasive Lesions of the Lower Genital Tract / Thomas C. Wright, Jr. 627

20 Vulva / David H. Moore, Wui-Jin Koh, William P. Mcguire, Edward J. Wilkinson 665

21 Vagina / Higinia R. Cardenes, Lawrence M. Roth, William P. McGuire, Katherine Y. Look 707

22 Uterine Cervix / Marcus E. Randall, Helen Michael, Jan Vermorken, Fred Stehman 743

23 Corpus: Epithelial Tumors / Claes G. Trope, Kaled M. Alektiar, Paul J. Sabbatini, Richard J. Zaino 823

24 Corpus: Mesenchymal Tumors / Gregory Sutton, John Kavanagh, Aaron Wolfson, Carmen Tornos 873

25 Epithelial Ovarian Cancer / Robert F. Ozols, Stephen C. Rubin, Gillian M. Thomas, Stanley J. Robboy 895

26 Ovarian Germ Cell Tumors / Daniela E. Matei, Anthony H. Russell, Carolyn J. Horowitz, David M. Gershenson, Elvio Silva 989

27 Ovarian Sex Cord-Stromal Tumors / David M. Gershenson, Lynn C. Hartmann, Robert H. Young 1011

28 Carcinoma of the Fallopian Tube / Maurie Markman, Richard J. Zaino, Peter A. Fleming, Mary L. Gemignani 1035

29 Gestational Trophoblastic Diseases / Ross S. Berkowitz, Donald P. Goldstein 1055

30 Breast Cancer / Beryl M. McCormick, Clifford Hudis, Mary Gemignani, D. David Dershaw, Lee K. Tan, Carlos A. Perez, Marie E. Taylor 1077

Section IV. Special Management Topics 1171

31 Management of Infections in Gynecologic Cancer Patients / Kent A. Sepkowitz, David L. Hemsell, Donald Armstrong 1173

32 Management of Late Effects of Gynecologic Cancer Treatment / David G. Mutch, Perry W. Grigsby, Maurie Markman, Stephen C. Rubin 1193

33 Management of Pain / Russell K. Portenoy, Annette Vielhaber, Pauline Lesage 1215

34 Rehabilitation as an Integrative Model: Psychologic and Surgical Approaches / Paul-George Knapstein, Sabine Hawighorst-Knapstein, Christian Stief, Michael Krychman, Douglas A. Levine 1241

35 Nutritional Support of Patients with Gynecologic Cancers / Moshe Shike, Mark Schattner 1263

36 Cancer in the Pregnant Patient / Ron E. Swensen, Barbara A. Goff, Wui-Jin Koh, Stephen J. Petersdorf, James G. Douglas, Elizabeth M. Swisher, Benjamin E. Greer 1279

37 AIDS and Women / Mary Jo Lechowicz, Otis W. Brawley 1313

38 Quality of Life Issues in Gynecologic Cancer / Lari B. Wenzel, David Cella 1333

39 End of Life Care / Joanna M. Cain, Peter A. Heintz, Nikkie B. Swarte 1343

Appendix Source Information on International, National, and Grant-Making Organizations of Relevance to Gynecologic Oncology / Edward L. Trimble, Sergio Pecorelli 1361.

Notes:

Includes bibliographical references and index.

Local Notes:

Acquired for the Penn Libraries with assistance from the Louis A. Duhring Fund.

ISBN:

0781746892

OCLC:

55887373