Late-life depression / edited by Steven P. Roose, Harold A. Sackeim.

Format:

Book

Contributor:

Roose, Steven P., 1948-

Sackeim, Harold A.

Language:

English

Subjects (All):

Depression in old age.

Geriatric psychiatry.

Depressive Disorder.

Aged.

Aged--psychology.

Medical Subjects:

Depressive Disorder.

Aged.

Aged--psychology.

Physical Description:

xxiii, 388 pages, 4 unnumbered pages of plates : illustrations (some color) ; 29 cm

Place of Publication:

New York : Oxford University Press, 2004.

Summary:

We live in an aging world. As a result, in years to come illnesses that are prevalent and cause significant morbidity and mortality in older people will consume an increasing share of health-care resources. One such illness is depression. This illness has a particularly devastating impact in the elderly because it is often undiagnosed or inadequately treated. Depression not only has a profound effect on the quality of life but it is also associated with an increased risk of mortality from suicide and vascular disease. In fact for every medical illness studied (e.g., heart disease, diabetes, cancer), individuals who are depressed have a worse prognosis. Research has illuminated the physiological and behavioral effects of depression that account for these poor outcomes. The deleterious relationship between depression and other illnesses has changed the concept of late-life depression from a "psychiatric disorder" that is diagnosed and treated by a psychiatrist to a common and serious disorder that is the responsibility of all physicians who care for patients over the age of 60 years.

This is the first volume devoted to the epidemiology, phenomenology, psychobiology, treatment, and consequences of late-life depression. Although much has been written about depressive disorders, the focus has been primarily on the illness as experienced in younger adults. The effects of aging on the brain, the physiological and behavioral consequences of recurrent depression, and the impact of other diseases common in the elderly make late-life depression a distinct entity. There is a compelling need for a separate research program, specialized treatments, and a book dedicated to this disorder. This volume will be invaluable to psychiatrists, gerontologists, clinical psychologists, social workers, students, trainees, and others who care for individuals over the age of 60 years.

Contents:

Part I Epidemiology and the Burden of Illness

1. The Epidemiology of Depressive Disorders in Late Life / Dan G. Blazer 3

2. The Social and Financial Burden of Late-Life Depression to Society and Individuals / Barry D. Lebowitz, Jason T. Olin 12

Part II The Phenomenology and Differential Diagnosis of Late-Life Mood Disorders

3. Unipolar Depression / George S. Alexopoulos, William Apfeldorf 21

4. Bipolar Disorders / Robert C. Young 34

5. Dysthymic Disorder in the Elderly / D.P. Devanand 49

6. Nonmajor Clinically Significant Depression in the Elderly / Anand Kumar, Helen Lavretsky, Virginia Elderkin-Thompson 64

7. Mixed Cognitive and Depressive Syndromes / Helen Lavretsky, Gary W. Small 81

8. Suicide / Yeates Conwell 95

9. Bereavement and Depression / Paula J. Clayton 107

Part III The Psychobiology of Late-Life Depression

10. Neuropsychological Assessment of Late-Life Depression / Wilfred G. Van Gorp, James C. Root, Harold A. Sackeim 117

11. Structural and Functional Brain Imaging in Late-Life Depression / Harold A. Sackeim 129

12. Late-Life Depression and the Vascular Hypothesis / K. Ranga R. Krishnan 148

13. Hypothalamic-Pituitary-Adrenal Axis Activity in Mood and Cognition in the Elderly: Implications for Symptoms and Outcomes / Jennifer Keller, Theresa M. Buckley, Alan F. Schatzberg 157

14. The Neuroendocrinology of Aging / Stuart N. Seidman 167

Part IV Treatment

15. Pharmacokinetics and Pharmacodynamics in Late Life / Bruce G. Pollock 185

16. Antidepressant Medication for the Treatment of Late-Life Depression / Steven P. Roose, Harold A. Sackeim 192

17. Antidepressant Side Effects / Carl Salzman 203

18. Mood Stabilizers / Charles L. Bowden 211

19. Stimulants / J. Craig Nelson 222

20. Antipsychotics / Christian R. Dolder, Jonathan P. Lacro, Dilip V. Jeste 232

21. Electroconvulsive Therapy in Late-Life Depression / Harold A. Sackeim 241

22. Pharmacological Treatment of Depression in Alzheimer's Disease / John L. Beyer, P. Murali Doraiswamy 279

23. Psychotherapy in Old-Age Depression: Progress and Challenges / Charles F. Reynolds III, Patricia A. Arean, Thomas R. Lynch, Ellen Frank 287

24. Treatment of Depression in Residential Settings / Ira R. Katz, Joel Streim 299

Part V Depression Co-Morbid with Other Illnesses

25. Depression Co-Morbid with Ischemic Heart Disease / Steven P. Roose, Alexander H. Glassman 311

26. Vascular Disease and Late-Life Depression: Stroke / Robert G. Robinson 321

27. Substance Abuse Co-Morbidity / David W. Oslin 337

28. Basal Ganglia Disease and Depression / Anjan Chatterjee, Karen Marder 348

29. Major Depressive Disorder in Alzheimer's Disease / George S. Zubenko 361.

Notes:

Includes bibliographical references and index.

ISBN:

0195152743

OCLC:

53926699