The pneumococcus / volume editor, Elaine I. Tuomanen ; associate editors, Timothy J. Mitchell, Donald Morrison, Brian G. Spratt.

Format:

Book

Contributor:

Tuomanen, Elaine I.

Language:

English

Subjects (All):

Streptococcus pneumoniae.

Streptococcus pneumoniae--pathogenicity.

Streptococcus pneumoniae--physiology.

Pneumococcal Infections--physiopathology.

Pneumococcal Infections--prevention & control.

Medical Subjects:

Streptococcus pneumoniae--pathogenicity.

Streptococcus pneumoniae--physiology.

Pneumococcal Infections--physiopathology.

Pneumococcal Infections--prevention & control.

Physical Description:

xxx, 427 pages, viii pages of plates : illustrations (some color) ; 26 cm

Place of Publication:

Washington, DC : ASM Press, [2004]

Summary:

- Written by the most comprehensive group of influential experts assembled to date in the field- State-of-the-art coverage combining clinical medicine and basic microbiology in a single reference source- Comprehensive foreword written by Robert Austrian- Includes valuable historical perspective and likely directions for future pneumococcal research- Addresses subject areas not previously covered, including evolution of genomes, fitness for colonization or disease, and new aspects of innate immunity

Contents:

The bacteria

Genome

What is a pneumococcus? / Christopher G. Dowson

Comparative genomics of streptococcus pneumoniae: intrastrain diversity and genome plasticity / Hervé Tettelin and Susan Hollingshead

Surface anatomy

Capsules / Janet Yother

Choline-binding proteins / Edwin Swiatlo, Larry S. McDaniel and David E. Briles

Pneumolysin and other virulence proteins / Tim J. Mitchell

Microbial physiology

Cell wall hydrolases / Rubens Lopez ... [et al.]

Transformation / Sanford A. Lacks

Host-microbe interactions

Exposure and colonization

Evolutionary and population biology of streptococcus pneumoniae / Brian G. Spratt, William P. Hanage and Angela B. Brueggemann

Pneumococcal carriage / Derrick W. Crook ... [et al.]

Epidemiology of pneumococcal disease / Jay C. Butler

Mechanisms of carriage / Jeffrey N. Weiser

Invasion and infection

Inflammation and host defense / Paul Anthony Majcherczyk and Philippe Moreillon

Interactions of streptococcus pneumoniae with the proteins of the complement pathways / Margaret K. Hostetter

A pathogenetic categorization of clinical syndromes caused by streptococcus pneumoniae / Daniel M. Musher

Attachment and invasion of the respiratory tract / Elaine I. Tuomanen

Pathogenesis of pneumococcal meningitis / Joerg R. Weber

Immunodeficiency and invasive pneumococcal disease / Edward N. Janoff and Jeffrey B. Rubins

Treatment and prevention

Changing the ecology of pneumococci with antibiotics and vaccines / Ron Dagan and Marc Lipsitch

Pneumococcal infections: therapeutic strategies and pitfalls / Kathryn M. Edwards

Clinical relevance of antibiotic resistance in pneumococcal infections / Keith P. Klugman

Mechanisms for penicillin resistance in streptococcus pneumoniae: penicillin binding proteins, gene transfer, and cell wall metabolism / Carina Bergmann ... [et al.]

Macrolide, quinolone, and other non-β-lactam antibiotic resistance in streptococcus pneumoniae / Karita Ambrose and David S. Stephens

The humoral immune response to streptococcus pneumoniae / Clifford M. Snapper ... [et al.]

New pneumococcal vaccines: basic science developments / James C. Paton

Vaccine-induced immunity to pneumococcal infection / P. Helena Mäkelȧ and Helena Käyhty.

Notes:

Includes bibliographical references and index.

ISBN:

155581297X

OCLC:

54454772