Infection and immunity / John H. L. Playfair, Gregory J. Bancroft.

Format:

Book

Author/Creator:

Playfair, J. H. L.

Contributor:

Bancroft, Gregory J.

Language:

English

Subjects (All):

Immunology.

Infection.

Immunity--immunology.

Immune System.

Infections.

Medical Subjects:

Immunity--immunology.

Immune System.

Infections.

Physical Description:

xvi, 312 pages : illustrations ; 25 cm

Edition:

Second edition.

Place of Publication:

Oxford ; New York : Oxford University Press, 2004.

Summary:

The second edition of Infection and Immunity explains how, in the lucid, accessible style for which John Playfair is well known, and with extensive new input from Gregory Bancroft, an expert in infectious diseases. The authors describe the main causes of infection -- from viruses to worms -- and explain the intricate ways in which the body responds to infection, from detection of potentially dangerous organisms, to their ultimate elimination and how this can fail. With examples of infectious diseases from across the world, and with vastly expanded coverage compared to the first edition, the second edition of Infection and Immunity is the perfect resource for biomedical science, bioscience, microbiology, and epidemiology students who need to understand what causes infection, and how our immune systems respond.

Contents:

Part 1 The infectious organisms

1. Introduction: parasites, pathogens, and immunity 3

2. Viruses 11

3. Bacteria 19

4. Fungi 27

5. Protozoa 31

6. Helminths (worms) 39

7. Prions 47

8. Disease: virulence and susceptibility 49

Part 2 The immune system

9. External defences: entry and exit 61

11. Innate immunity 77

12. How pathogens escape innate immunity 95

13. Disease due to innate immunity 101

14. Immunodeficiency I: primary defects of innate immunity 107

15. Adaptive immunity: introduction 117

16. B cells and antibody 125

17. T cells and the MHC 135

18. The antibody response 147

19. Cell-mediated responses 157

20. Regulation of immune responses and memory 167

21. How pathogens escape adaptive immunity 175

22. Disease due to adaptive immunity I: hypersensitivity 185

23. Disease due to adaptive immunity II: autoimmunity 193

24. Immunodeficiency II: primary defects of adaptive immunity 201

25. Immunodeficiency III: secondary immunodeficiency and AIDS 207

Part 3 The host-pathogen balance

26. Epidemiology 223

27. Control of infectious disease: vaccination 231

28. Control of infectious disease: chemotherapy 243

29. Control of infectious disease: public health measures 251

30. Viral and prion disease and immunity 255

31. Bacterial disease and immunity 261

32. Fungal disease and immunity 271

33. Protozoal disease and immunity 275

34. Helminth disease and immunity 281

35. Emerging and future infectious diseases 285

Appendix 1. The major pathogens of man 295

Appendix 2. Cytokines 297

Appendix 3. CD molecules 299.

Notes:

Includes bibliographical references (pages [301]-306) and index.

ISBN:

0199264953

OCLC:

55503136