Protein microarrays / edited by Mark Schena.

Format:

Book

Contributor:

Schena, Mark.

Language:

English

Subjects (All):

Protein microarrays.

Protein Array Analysis.

Medical Subjects:

Protein Array Analysis.

Physical Description:

xv, 469 pages, 20 unnumbered pages of plates : illustrations (some color) ; 27 cm

Place of Publication:

Sudbury, Mass. : Jones and Bartlett, [2005]

Summary:

This dynamic new volume conceived and edited by Mark Schena features twenty-four cutting-edge chapters from the leading laboratories in the hot new field of protein microarrays. Dr. Schena, who published the first two papers on DNA microarrays in 1995 and 1996, extends his original vision of parallelism and miniaturization to advance the protein microarray field, which promises important breakthroughs in disease diagnostics and drug discovery, as well as basic research on protein expression, development, the immune system, aging, behavior, and other issues central to medicine. Protein Microarrays is the first comprehensive treatment of protein microarray technology, and includes detailed descriptions of manufacturing methods, surface chemistry, detection strategies, and data analysis for antigen, antibody, and peptide microarray assays. The book also presents numerous biological applications and experimental protocols not available from any other source. Protein Microarrays is an exceptional treatise and essential reading for everyone in the proteomics and microarray field.

Contents:

Chapter 1 Principles of Protein Microarrays / Mark Schena 1

Chapter 2 Novel Strategies in Protein Microarray Generation and Detection / Yee-Peng Rina Lue, Su-Yin Dawn Yeo, Lay-Pheng Tan, Mahesh Uttamchandani, Grace Yi-Jun Chen, Shao Q. Yao 13

Chapter 3 Practical Guide to Protein Microarrays: Assay Systems, Methods, and Algorithms / Mikhail Soloviev, Jon Terrett 43

Chapter 4 Microarrays for the High-Throughput Analysis of Protein-Carbohydrate Interactions / William G. T. Willats 57

Chapter 5 Protein Microarrays: Principles and Limitations / Victor N. Morozov 71

Chapter 6 System-Oriented Proteomics Using Protein-Domain Microarrays / Alexsandra Espejo, Mark T. Bedford 107

Chapter 7 Colorimetric Microarray Assays for Rheumatoid Arthritis using a Recombinant Proteome Library / Stewart J. Lebrun 119

Chapter 8 Academic and Commercial Aspects of Protein Microarray Development / Seung-yong Seong 137

Chapter 9 Analyzing Proteins and Protein Modifications with ArrayTube Antibody Microarrays / Stefan Wolfl, Annegret Dummer, Larissa Pusch, Marina Pfalz, Lin Wang, Joachim H. Clement, Ines Leube, Ralf Ehricht 159

Chapter 10 Non-Contact Dispensing for Protein Microarrays / Thomas C. Tisone, John L. Tonkinson 169

Chapter 11 High Speed, High Efficiency Protein Printing by BioLP / Bradley R. Ringeisen, Jason A. Barron, David B. Krizman 187

Chapter 12 Putting the "Bio" in Biochips: Capture Agents for Protein Microarray Expression Profiling Platforms / David S. Wilson, Michael L. Phelan, Steffen Nock 199

Chapter 13 Protein Biochips for the Profiling of Allergen-Specific Antibodies / Christian Harwanegg, Susanne Spitzauer, Rudolf Valenta, Manfred W. Mueller, Reinhard Hiller 221

Chapter 14 Solid Supports for Protein Microarrays and Related Devices / Wlad Kusnezow, Timo Pulli, Olaf Witt, Jorg D. Hoheisel 247

Chapter 15 Protein Microarrays for Biosensor Applications / Michael G. Weller 285

Chapter 16 Technological Aspects of Protein Microarrays and Nanoarrays / Fan-Gang Tseng, Shih-Chang Lin, Da-Jen Yao, Haimei Huang, Ching-Chang Chieng 305

Chapter 17 Mega-Dense Nanoarrays: The Challenge of Novel Antibody Microarray Formats / Christer Wingren, Lars Montelius, Carl A. K. Borrebaeck 339

Chapter 18 INFINITI System: An Automated Multiplexing Protein Microarray Platform / Anupam Talapatra, Vijay Mahant, Ram Vairavan, Fareed Kureshy, Gary Hardiman 353

Chapter 19 Protein Microarrays for Analysis of Antibody Responses in Animals and Humans / Paul J. Utz, Lawrence Steinman, William H. Robinson 365

Chapter 20 G-Protein Coupled Receptor Microarrays: A Versatile Tool for Drug Discovery / Ye Fang, Yulong Hong, Jinlin Peng, Joydeep Lahiri 377

Chapter 21 Proteome-Scale Analysis of the Immune Response Against Pathogenic Microorganisms / Tito Bacarese-Hamilton, Julian Gray, Andrea Crisanti 387

Chapter 22 Development of Protein Microarrays for Drug Discovery / Jens O. Koopmann, Michael B. McAndrew, Jonathan M. Blackburn 401

Chapter 23 Development and Applications of Functional Protein Microarrays / James Ball, Barry Schweitzer, Paul Predki, Michael Snyder 421

Chapter 24 Enabling Tools for Protein Microarrays / Todd Martinsky 441.

Notes:

Includes bibliographical references and index.

ISBN:

0763731277

OCLC:

54686486