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Angiogenesis in brain tumors / edited by Matthias Kirsch and Peter McL. Black.
Holman Biotech Commons RC280.B7 A546 2004
Available
- Format:
- Book
- Series:
- Cancer treatment and research ; v. 117.
- Cancer treatment and research ; v. 117
- Language:
- English
- Subjects (All):
- Brain--Tumors.
- Brain.
- Neovascularization.
- Brain Neoplasms.
- Angiogenesis Inducing Agents.
- Medical Subjects:
- Brain Neoplasms.
- Angiogenesis Inducing Agents.
- Physical Description:
- xii, 358 pages : illustrations ; 25 cm.
- Place of Publication:
- Boston : Kluwer Academic Publishers, [2004]
- Summary:
- The mutual relationship between tumor growth and concomitant neovascularization offers important insight into the biology of brain tumors and the development of new treatment strategies. Many of the early findings in the biology of angiogenesis have been investigated using brain tumor models. Angiogenesis in Brain Tumors is part of the Cancer Treatment and Research book series and this volume provides an overview of the biology of angiogenesis in the central nervous system, the role of angiogenesis in brain tumor development and growth, and therapeutic applications including clinical trials.
- Contents:
- A Principles of Angiogenesis in the Central Nervous System 1
- 1. Vasculogenesis and Angiogenesis / Sybill Patan 3
- 2. Morphogenesis of Embryonic CNS Vessels / Haymo Kurz, Johannes Korn, Bodo Christ 33
- 3. Mathematical Modeling of Tumour-Induced Angiogenesis: Network Growth and Structure / Mark Chaplain, Alexander Anderson 51
- B Assessment of Angiogenesis in Neuro-Oncology 77
- 4. Histologic Measures of Angiogenesis in Human Primary Brain Tumors / Rebecca D. Folkerth 79
- 5. Angiogenesis in Transgenic Models of Multistep Angiogenesis / Ivan Radovanovic, Maria G. D'Angelo, Adriano Aguzzi 97
- 6. Models for Angiogenesis in Gliomas / Roland H. Goldbrunner, Martin Bendszus, Jorg-Christian Tonn 115
- 7. Protocol for Isolation of HCEC / Roland H. Goldbrunner, Martin Bendszus, Jorg-Christian Tonn 137
- 8. Protocol for MRI Monitoring of Orthotopic Glioma Growth in the Rat Brain / Roland H. Goldbrunner, Martin Bendszus, Jorg-Christian Tonn 139
- 9. Methods to Study Angiogenesis in vitro / Katrin Lamszus, Oliver Heese, Manfred Westphal 141
- 10. The Rabbit Corneal Pocket Assay for the Study of Angiogenesis / Lucia Morbidelli, Marina Ziche 147
- C Brain Tumor Related Angiogenesis 153
- 11. Role of Nitric Oxide in Tumor Angiogenesis / Lucia Morbidelli, Sandra Donnini, Marina Ziche 155
- 12. Angiogenesis-related Growth Factors in Brain Tumors / Katrin Lamszus, Oliver Heese, Manfred Westphal 169
- 13. Role of VEGF in Developmental Angiogenesis and in Tumor Angiogenesis in the Brain / Marcia Regina Machein, Karl H. Plate 191
- 14. Hypoxia and Hypoxia Inducible Factors (HIF) as Important Regulators of Tumor Physiology / Till Acker, Karl H. Plate 219
- 15. Vascular Microenvironment in Gliomas / Peter Vajkoczy, Michael D. Menger 249
- 16. Angiogenesis and Invasion in Gliomas / Lorenzo Bello, Carlo Giussani, Giorgio Carrabba, Mauro Pluderi, Francesco Costa, Andreas Bikfalvi 263
- 17. Metastasis and Angiogenesis / Matthias Kirsch, Gabriele Schackert, Peter McL. Black 285
- D Clinical Application in Neuro-Oncology 305
- 18. Inhibition of Angiogenesis as a Therapeutic Strategy Against Brain Tumors / Vinay K. Puduvalli 307
- 19. Anti-Angiogenic Chemotherapy in Central Nervous System Tumors / Mark W. Kieran 337.
- Notes:
- Includes index.
- ISBN:
- 1402077041
- OCLC:
- 53286472
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