When cells die II : a comprehensive evaluation of apoptosis and programmed cell death / edited by Richard A. Lockshin, Zahra Zakeri.

Format:

Book

Contributor:

Lockshin, R. A. (Richard A.)

Zakeri, Zahra, 1952-

Language:

English

Subjects (All):

Apoptosis.

Apoptosis--physiology.

Medical Subjects:

Apoptosis--physiology.

Physical Description:

xi, 549 pages, 4 unnumbered pages of plates : illustrations (some color) ; 25 cm

Other Title:

When cells die two

When cells die 2

Place of Publication:

Hoboken, N.J. : Wiley-Liss, [2004]

Summary:

Cell death is fast becoming one of the most dynamic areas of biological research -- involving as it does the study of apoptosis and programmed cell death and the role these phenomena play in development and homeostasis on the one hand, and aging and disease on the other. The profound implications for medicine and agriculture from the manipulation of these processes have spawned a deluge of research papers, articles, approaches, and methods -- making it difficult for scientists to get an overview of the field. When Cells Die II: A Comprehensive Evaluation of Apoptosis and Programmed Cell Death offers the most thorough, cutting-edge coverage of this field since publication of the acclaimed first edition. Leading international researchers present an up-to-date yet accessible survey ranging from the history of cell death science to its modern methodology. With the manipulation of programmed cell death in clinical situations now in the foreseeable future, When Cells Die II also addresses the role of apoptosis in specific organ systems -- the immune system, nervous system, and gastrointestinal tract -- as well as different disease states, including viral infection, cancer, and myocardial infarct. Expertly edited to provide detailed cross-referencing, consistency of style, and a logical progression of topics, When Cells Die II is the definitive resource for understanding current cell death science. It will prove an invaluable text for advanced undergraduate, graduate, and medical students, postdoctoral fellows, scientists, and clinicians in cell biology, immunology, developmental biology, neuroscience, and cancer research.

Contents:

Section I Cell Death Origin and Progression

Section II Biological Role of Cell Death in Development and Homeostasis

2 Cell Death: Shaping an Embryo / Zahra Zakeri, Richard A. Lockshin 27

3 Cell Death in Dictyostelium: Assessing a Genetic Approach / Jean-Pierre Levraud, Myriam Adam, Marie-Francoise Luciani, Laurence Aubry, Gerard Klein, Pierre Golstein 59

4 Programmed Cell Death in Drosophila Melanogaster / Loretta Dorstyn, Sharad Kumar 79

5 Cell Death in Plant Development and Defense / Ron Mittler, Alice Y. Cheung 99

6 Regulation of Apoptosis by Extracellular Matrix during Postembryonic Development in Xenopus laevis / Atsuko Ishizuya-Oka, Tosikazu Amano, Liezhen Fu, Yun-Bo Shi 123

7 Apoptosis in the Immune System / Alexandra Bras, David Garcia-Domingo, Carlos Martinez-A 143

8 Cell Death in Neuronal Development and Maintenance / Aviva M. Tolkovsky, Edward T. W. Bampton, Cristoph G. Goemans 175

9 Cell turnover: Intestine and Other Tissues / James W. Wilson, Christopher S. Potten 201

10 Cell Death, Aging Phenotypes, and Models of Premature Aging / Huber R. Warner 241

Section III How Cell Death is Carried Out

11 Survival Factors / David L. Vaux 257

12 Caspase-independent and Autophagic Programmed Cell Death / Wilfried Bursch, Adolf Ellinger, Christopher Gerner, Rolf Schulte-Hermann 275

13 The Recognition and Engulfment of Apoptotic Cells by Phagocytes / Raymond B. Birge 311

14 Cell Cycle Genes: pRb and p53 / Nianli Sang, Antonio Giordano 339

15 Mitochondria and Oxidation in the Regulation of Cell Death / John D. Robertson, Sten Orrenius, Boris Zhivotovsky 381

Section IV Deregulation of Cell Death in Disease and Future Intervention

16 The Use of Proteomics to Identify and Characterize Cell Death Proteins / Xavier Saelens, Geert van Loo, Kris Gevaert, Joel Vanderkerckhove, Peter Vandenabeele 405

17 Cell Death in Viral Infections / Ying-bei Chen, Yihru Fannjiang, J. Marie Hardwick 435

18 Cell Death in Cancer and Cancer Therapy / Simone Fulda, Klaus-Michael Debatin 461

19 The Role of Apoptosis in Myocardial Infarction and Heart Failure / Kartik Mani, Chang-Fu Peng, Gregg Rosner, Richard N. Kitsis 483.

Notes:

Includes bibliographical references and index.

ISBN:

0471219479

OCLC:

52127417

Online:

Publisher description