Endocrine aspects of successful aging : genes, hormones and lifestyles / P. Chanson ... [and others] (eds.).

Format:

Book

Contributor:

Chanson, P. (Philippe)

Series:

Research and perspectives in endocrine interactions

Language:

English

Subjects (All):

Aging--physiology.

Aging--Endocrine aspects.

Hormones--physiology.

Life Style.

Aging--Endocrine aspects--Congresses.

Aging.

Medical Subjects:

Aging--physiology.

Hormones--physiology.

Life Style.

Genre:

Conference papers and proceedings.

Physical Description:

xii, 231 pages : illustrations (some color) ; 24 cm.

Place of Publication:

Berlin ; New York : Springer, 2004.

Summary:

At the beginning of the 20th century, life expectancy at birth in North America and Western Europe was around 50 years of age. Nowadays, women have gained more than 30 years of age and men are trailing closer. However, according to several scientists and sociologists, such as Louis Chauvel, the notion of a "greying society" is not entirely adequate since aging people are physically and socially younger and more active for a longer time. Of course, the other side of the medal is to tackle the challenge of preventing age-associated chronic diseases. In this book the extensive field of research on neuroendocrine aging has been reviewed, including data from molecular biology and on simple organisms as well as on the hormonal substitution strategies in humans. Aging is one of the most complex biological processes determined by the interactions between genetic and environmental factors.

Contents:

Regulation of C. elegans Life Span by Insulin-Like Signaling / G. Ruvkun 1

IGF-1 and Insulin Signaling in the Control of Longevity / A. Bartke, J. Kopchick, F. Dominici, D. Turyn 19

IGF-1 Receptors in Mammalian Longevity: Less is More / M. Holzenberger 35

IGF-1 Gene Polymorphism and Disease in the Elderly / J.A.M.J.L. Janssen, S.W.J. Lamberts 49

Polymorphisms and Male Ageing / M. Jiang, I. Huhtaniemi 63

Age-Related Changes in the Regulation of the Hypothalamic-Pituitary Adrenal Axis: the Role of Personality Variables / J.C. Pruessner, C. Lord, R. Renwick, M. Meaney, S. Lupien 89

Aging White Matter and Cognitive Decline: A Role for Steroids / M. Schumacher, C. Ibanez, F. Robert, L.M. Garcia-Segura, R. Franklin, R. Melcangi 101

How Do Changes in the GH/IGF-1 Status of the Elderly - Whether Occurring Naturally, Pathologically or Therapeutically Induced - Impact Their Lives? / S.K. AA. Shakoor, A.A. Toogood, S.M. Shalet 129

Estrogen and Cognitive Functioning in Women / B.B. Sherwin 149

Genetic Polymorphisms and Age-Related Diseases: the Example of Osteoporosis / A.G. Uitterlinden, H. A. P. Pols 157

Are Estrogens Protective or Risk Factors in the Brain? Insights Derived from Animal Models / P.M. Wise, D.B. Dubal 165

Testosterone Supplementation and Aging-Associated Sarcopenia / S. Bhasin 175

The Long Thread of GFAP in Aging, Steroids, and Synaptic Plasticity / C.E. Finch, T.E. Morgan, I. Rozovsky, M. Wei 191

Circadian Rhythmicity and Aging: The Molecular Basis of Oscillatory Gene Expression / P. Sassone-Corsi 207

Prediction of Death in the Elderly Men: Endocrine Factors / A.W. van den Beld, S.W.J. Lamberts 217.

Notes:

"Second meeting of the series Research and perspectives in endocrine interactions, organized in Paris by the Foundation IPSEN on December 3, 2002"--Pref.

Includes bibliographical references and index.

ISBN:

3540405739

OCLC:

54074227