Bacterial adhesion to animal cells and tissues / Itzhak Ofek, David L. Hasty, Ron J. Doyle.

Format:

Book

Author/Creator:

Ofek, Itzhak.

Contributor:

Hasty, David L.

Doyle, Ronald J.

Ofek, Itzhak.

Language:

English

Subjects (All):

Bacteria--Adhesion.

Bacteria.

Cell adhesion molecules.

Bacterial Adhesion.

Adhesins, Bacterial.

Medical Subjects:

Bacterial Adhesion.

Adhesins, Bacterial.

Physical Description:

x, 416 pages : illustrations ; 26 cm

Place of Publication:

Washington, D.C. : ASM Press, [2003]

Summary:

The adhesion of bacteria to host cells is a critical event in the development of bacterial infections. Knowledge of the molecular mechanisms of this process is key to understanding an essential step in pathogenesis and to identifying potential targets for antimicrobial therapy. This authoritative volume covers historical perspectives, general principles, methodologies, specific host cell and bacterial components associated with the process, including post-adhesion consequences, regulation of adhesin expression, and anti-adhesion therapy. Bacterial Adhesion to Animal Cells and Tissues is an essential reference for students and investigators interested in host-pathogen interactions.

Contents:

Basic concepts in bacterial adhesion

Methodological approaches to analysis of adhesins and adhesion

Target tissues for bacterial adhesion

Adhesins as bacterial cell surface structures: general concepts of structure, biogenesis, and regulation

Emerging concepts in bacterial adhesion and its consequences

Diversification of receptor specificity and its biological consequences

Entry of bacteria into nonphagocytic cells

Postadhesion events induced in nonphagocytic cells

Adhesion-dependent upregulation of bacterial genes

Role of adhesion in biofilm formation

Antiadhesion therapy

Adhesins, receptors and target substrata involved in the adhesion of pathogenic bacteria to host cells and tissues.

Notes:

Updates: Bacterial adhesion to cells and tissues / Itzhak Ofek and Ronald J. Doyle, 1994.

Includes bibliographical references and index.

Related Work:

Ofek, Itzhak. Bacterial adhesion to cells and tissues.

ISBN:

1555812635

OCLC:

51857080