Animal models of human inflammatory skin diseases / edited by Lawrence S. Chan.

Format:

Book

Contributor:

Chan, Lawrence S.

Language:

English

Subjects (All):

Animal models.

Skin--Inflammation--Animal models.

Skin.

Alopecia areata--Animal models.

Alopecia areata.

Skin--Inflammation.

Physical Description:

564 pages : illustrations ; 26 cm

Place of Publication:

Boca Raton, Fla. ; London : CRC Press, [2004]

Contents:

Part I Comparative Structure and Function of the Skin 1

Chapter 1 Comparative Structure and Function of the Skin: Overview of Structures and Components / Lawrence S. Chan 3

Chapter 2 Comparative Structure and Function of the Skin: Epithelial Basement Membrane Zone / Lawrence S. Chan 19

Part II Comparative Immunology 31

Chapter 3 Human Immune System / Kalyanasundaram Ramaswamy 33

Chapter 4 Canine Immune System / Bruce Hammerberg 79

Chapter 5 Rat Immune System / Kevin J. McElwee, Birte Steiniger 91

Chapter 6 Mouse Immune System / Lawrence S. Chan, Kenneth B. Gordon 119

Part III Immune Privilege and Skin Inflammation 141

Chapter 7 Immune Privilege of the Eye / Jerry Y. Niederkorn 143

Chapter 8 The Theory of Immune Privilege of the Hair Follicle / Ralf Paus, Natsuho Ito, Taisuke Ito 155

Part IV Methods of Experimental Animal Modeling 167

Chapter 9 Passive Transfer and Active Induction of Autoimmune Diseases / Zhi Liu, Minglang Zhao, Luis A. Diaz 169

Chapter 10 Adoptive Transfer of Cellular Immunity / Lawrence S. Chan 179

Chapter 11 Molecular Biological Manipulation of the Immune System by Transgenic Techniques / Lawrence S. Chan 187

Part V Inflammatory Skin Disease Models 197

Section A Bullous Pemphigoid 199

Chapter 12 Natural Bullous Pemphigoid in Companion Animals / Thierry Olivry 201

Chapter 13 Experimental Mouse Model of Bullous Pemphigoid: Passive Transfer of Anti-BP180 Type XVII Collagen, Antibodies / Zhi Liu, Luis A. Diaz 213

Section B Epidermolysis Bullosa Acquisita 225

Chapter 14 Spontaneous Canine Model of Epidermolysis Bullosa Acquisita / Thierry Olivry 227

Section C Mucous Membrane Pemphigoid 239

Chapter 15 Spontaneous Canine Model of Mucous Membrane Pemphigoid / Thierry Olivry 241

Chapter 16 Experimental Mouse Model of Mucous Membrane Pemphigoid: Passive Transfer of Anti-Laminin 5 Antibodies / Zelmira Lazarova 251

Section D Pemphigus Vulgaris 261

Chapter 17 Spontaneous Canine Model of Pemphigus Vulgaris / Thierry Olivry 263

Chapter 18 Experimental Mouse Model of Pemphigus Vulgaris: Passive Transfer of Desmoglein-Targeting Antibodies / Zelmira Lazarova, Grant J. Anhalt 275

Chapter 19 Experimental Mouse Model of Pemphigus Vulgaris: Passive Transfer of Nondesmoglein 1 and 3 Antibodies / Vu Thuong Nguyen 285

Section E Pemphigus Foliaceus 307

Chapter 20 Spontaneous Canine Model of Pemphigus Foliaceus / Toshiroh Iwasaki, Thierry Olivry 309

Chapter 21 Experimental Mouse Model of Pemphigus Foliaceus: Passive Transfer of Desmoglein-Targeting Antibodies / David S. Rubenstein, Simon J. Warren, Ning Li, Zhi Liu, Luis A. Diaz 321

Section F Psoriasis 329

Chapter 22 Experimental Chimeric SCID Mouse/Human Skin Model of Psoriasis: Induction by Transfer of Cellular Immunity / Jonathan L. Curry, Brian J. Nickoloff 331

Chapter 23 Experimental Mouse Model of Psoriasis by Transgenic Expression of Integrin / Joseph M. Carroll 341

Section G Atopic Dermatitis 351

Chapter 24 Spontaneous Canine Model of Atopic Dermatitis / Andrew Hillier, Thierry Olivry 353

Chapter 25 Spontaneous Mouse Model of Atopic Dermatitis in NC/Nga Mice / Keiko Kawamoto, Hiroshi Matsuda 371

Chapter 26 Experimental Mouse Model of Atopic Dermatitis by Transgenic Induction / Lawrence S. Chan 387

Chapter 27 Experimental Mouse Model of Atopic Dermatitis: Induction by Oral Allergen / Xiu-Min Li, Hugh A. Sampson 399

Chapter 28 Experimental Mouse Model of Atopic Dermatitis: Induction by Epicutaneous Application of Allergen / Jonathan M. Spergel 417

Section H Alopecia Areata 427

Chapter 29 Spontaneous and Experimental Skin-Graft-Transfer Mouse Models of Alopecia Areata / John P. Sundberg, Kevin J. McElwee, Lloyd E. King, Jr. 429

Chapter 30 Spontaneous Rat Model of Alopecia Areata in the Dundee Experimental Bald Rat (DEBR) / Kevin J. McElwee 451

Chapter 31 Spontaneous Canine Model of Alopecia Areata / Desmond J. Tobin, Thierry Olivry 469

Chapter 32 Experimental Chimeric SCID Mouse/Human Skin Model of Alopecia Areata: Induction by Transfer of Cellular Immunity / Richard S. Kalish, Amos Gilhar 483

Section I Scleroderma 493

Chapter 33 Spontaneous Mouse Models of Systemic Scleroderma / Paul J. Christner, Sergio A. Jimenez 495

Chapter 34 Experimental Mouse Model of Scleroderma/Graft versus Host Disease: Induction by Transfer of Cellular Immmunity / Anita C. Gilliam 517

Chapter 35 Experimental Mouse Model of Scleroderma: Induction by Bleomycin / Toshiyuki Yamamoto 535.

Notes:

Includes bibliographical references and index.

ISBN:

0849313910

OCLC:

52919409