Gastrointestinal and liver tumors / W. Scheppach, R. S. Bresalier, and G. N. J. Tytgat, eds.

Format:

Book

Contributor:

Scheppach, W. (Wolfgang)

Bresalier, R. S. (Robert S.)

Tytgat, G. N. J.

Language:

English

Subjects (All):

Gastrointestinal system--Tumors.

Gastrointestinal system.

Liver--Tumors.

Liver.

Digestive System Neoplasms.

Medical Subjects:

Digestive System Neoplasms.

Physical Description:

xviii, 334 pages : illustrations (some color) ; 25 cm

Place of Publication:

Berlin ; New York : Springer, [2004]

Summary:

This book covers all aspects of gastrointestinal and liver malignancies (epidemiology, pathophysiology, screening where appropriate, symptoms and clinical signs, diagnostic studies, staging and classification, treatment, prognosis, follow-up, future perspectives). It is addressed to those involved in the multidisciplinary approach to the gastrointestinal cancer patient (gastroenterologists, medical oncologists, radiation therapists, surgeons, interventional radiologists, pathologists, nurses, and physicians-in-training). The book provides in-depth information, illustrated by numerous color/black-and-white pictures. Selective reading for a quick reference is made possible by introducing text elements such as summaries, tables, listing and treatment algorithms.

Contents:

I Esophagus

1 Squamous Cell Carcinoma of the Esophagus / S.J. Spechler 3

Epidemiology 3

Etiology 3

Symptoms and Clinical Signs 4

Diagnostics 4

Histological Classification and Molecular Genetics 6

Staging 7

Treatment 8

Prognosis and Follow-Up 10

Future Perspectives 11

2 Adenocarcinoma of the Esophagus / O. Pech, A. May, L. Gossner, C. Ell 12

Epidemiology 12

Etiology and Pathogenesis 12

Symptoms and Clinical Signs 12

Diagnosis 13

Histological Classification and Molecular Genetics 16

Staging 16

Treatment 17

Prognosis 21

Future Perspectives 21

3 Other Tumors of the Esophagus / R. Lambert, J.Y. Scoazec 22

Mesenchymal Tumors of the Esophagus 22

Endocrine Tumors of the Esophagus 27

Lymphoma of the Esophagus 30

Secondary Tumors of the Esophagus 32

Melanoma of the Esophagus 33

II Stomach

4 Gastric Cancer / A.T.R. Axon, M.F. Dixon, H.M. Sue-Ling 37

Epidemiology 37

Etiology and Pathogenesis 38

Symptoms and Clinical Signs 43

Diagnostics 44

Histological Classification and Molecular Genetics 47

Staging 49

Treatment 51

Prognosis 55

Follow-Up 55

Future Perspectives 57

5 Lymphoma of the Stomach / B.A. Dragosics 59

Epidemiology 59

Etiology and Pathogenesis 60

Symptoms and Clinical Signs 60

Diagnostics 61

Histological Classification and Molecular Genetics 64

Staging 65

Treatment 66

Prognosis and Follow-Up 68

Future Perspectives 69

6 Gastric Tumors Other than Adenocarcinoma and Lymphoma / N.C.T. van Grieken, G.A. Meijer, E.J. Kuipers 70

Epithelial Tumors 70

Mesenchymal Tumors of the Stomach 78

III Small Intestine

7 Neoplasms of the Small Intestine / K. Geboes, C. de Wolf-Peeters 83

Epidemiology 83

Etiology 85

Symptoms and Clinical Signs 86

Diagnostics 87

Histological Classification and Molecular Genetics 87

Staging 92

Treatment 93

Prognosis and Follow-Up 94

Future Perspectives 95

IV Colon and Rectum

8 Colorectal Cancer / R.S. Bresalier, S.B. Ho 99

Epidemiology 99

Etiology and Pathogenesis 99

Symptoms and Clinical Signs 101

Diagnostics 103

Histological Classification and Molecular Genetics 104

Staging 109

Treatment 110

Future Perspectives 116

9 Sporadic Adenomas of the Large Intestine / S.B. Ho, J.H. Bond 117

Epidemiology 117

Etiology and Pathogenesis 117

Symptoms and Clinical Signs 118

Diagnostics 118

Histological Classification and Molecular Genetics 119

Treatment 121

Future Perspectives 123

10 Hereditary Polyposis Syndromes / J.M. Carethers 125

Adenomatous Polyposis Syndromes 125

Hamartomatous Polyposis Syndromes 132

Juvenile Polyposis Syndrome (JPS) 138

Hereditary Mixed Polyposis Syndrome (HMPS) 139

11 Hereditary Nonpolyposis Colorectal Cancer (Lynch Syndrome) / H.T. Lynch, J.F. Lynch 142

Epidemiology 142

Etiology and Pathogenesis 142

Symptoms and Clinical Signs 143

Diagnostics 143

Histological Classification and Molecular Genetics 154

Staging 154

Treatment 155

Prognosis 156

Follow-Up 156

Future Perspectives 158

12 Colorectal Cancer in Inflammatory Bowel Disease / V. Croog, S.H. Itzkowitz 160

Epidemiology 160

Etiology and Pathogenesis 161

Symptoms and Clinical Signs 161

Diagnostics 161

Histological Classification and Molecular Genetics 162

Staging 162

Treatment 162

Prognosis and Follow-Up 163

Future Perspectives 165

V Anal Canal

13 Anal Carcinoma / J.C. Eggenberger 169

Epidemiology 169

Etiology and Pathogenesis 169

Symptoms and Clinical Signs 170

Diagnostics 170

Histological Classification and Molecular Genetics 170

Staging 173

Treatment 173

Prognosis 175

Follow-Up 176

Future Perspective 177

VI Pancreas

14 Neoplastic Lesions of the Pancreas / H.G. Beger, M. Siech 181

Adenocarcinoma of the Pancreas 181

Cystic Carcinoma of the Pancreas 188

Other Tumors 190

VII Neuroendocrine Gastro-Entero-Pancreatic Tumors

15 Neuroendocrine Gastro-Entero-Pancreatic (GEP) Tumors / R. Arnold, R. Goke, M. Wied, Th. Behr 195

Classification 197

Epidemiology 198

Etiology 199

General Pathophysiology 199

Histopathology 199

Molecular Pathogenesis 202

Growth Characteristics and Metastatic Spread and Secondary Non-Endocrine Malignancies 204

Staging of Endocrine GEP Tumors 206

Clinical Entities: Symptoms and Laboratory Findings 206

General Aspect of Management 229

VIII Biliary System and Papilla of Vater

16 Carcinoma of the Gallbladder and Bile Ducts / K. Schoppmeyer, K. Caca, J. Mossner 237

Epidemiology 237

Etiology 237

Symptoms and Clinical Signs 238

Diagnostics 238

Histological Classification and Molecular Genetics 241

Staging 242

Treatment 244

Prognosis and Follow-Up 246

Future Perspectives 246

17 Benign Tumors of the Biliary System / K. Schoppmeyer, K. Caca, J. Mossner 248

Epidemiology 248

Etiology 248

Symptoms and Clinical Signs 248

Diagnostics 248

Histological Classification and Molecular Genetics 249

Staging 250

Treatment 250

Prognosis and Follow-Up 250

Future Perspectives 251

18 Malignant Tumors of the Ampulla of Vater / W. Scheppach, H.-J. Gassel, J. G. Mueller 252

Epidemiology 252

Etiology 252

Symptoms and Clinical Signs 252

Diagnostics 253

Histological Classification and Molecular Genetics 254

Staging 255

Treatment 256

Prognosis and Follow-Up 257

Future Perspectives 258

IX Liver

19 Hepatocellular Carcinoma / M. Scheurlen, H.-J. Brambs, H.-J. Gassel 261

Epidemiology 261

Etiology and Pathogenesis 261

Symptoms and Clinical Signs 262

Diagnostics 263

Histological Classification 267

Staging 268

Treatment 269

Prognosis 276

Follow-Up 277

Future Perspectives 278

20 Colorectal Liver Metastases / H.-J. Gassel, M. Gasser, A.M. Waaga-Gasser, W. Timmermann 280

Epidemiology 280

Etiology and Pathogenesis 280

Symptoms and Clinical Signs 281

Diagnostics 281

Histological Classification and Molecular Genetics 283

Treatment 284

Prognosis 287

Follow-Up 288

Future Perspective 288

21 Liver Metastases of Noncolorectal Cancer / W. Timmermann, R. Kellersmann, H.-J. Gassel 289

Epidemiology 289

Symptoms and Clinical Signs 289

Diagnostics 289

Histological Classification and Molecular Genetics 291

Treatment 291

Prognosis and Follow-Up 291

Future Perspectives 292

22 Benign Liver Tumors / E. Biecker, H.P. Fischer, H. Strunk, T. Sauerbruch 295

Epidemiology 295

Etiology 296

Symptoms and Clinical Signs 297

Diagnostics 298

Histological Classification and Molecular Genetics 304

Treatment 308

23 Supportive Care of Patients with Gastrointestinal and Liver Tumors / W. Scheppach 315

Nutritional Support 315

Analgesic Therapy 320

Antiemetic Therapy 322

Management of Malignancy-Related Ascites 324

Management of Bowel Obstruction Due to Peritoneal Carcinomatosis 326

End-of-life Care 327

Calculation of Body Surface Area.

Notes:

Includes bibliographical references and index.

ISBN:

3540434623

OCLC:

54034843