Bioinformatics and functional genomics / Jonathan Pevsner.

Format:

Book

Author/Creator:

Pevsner, Jonathan, 1961-

Language:

English

Subjects (All):

Genomics.

Bioinformatics.

Proteomics.

Genetics--Data processing.

Genetics.

Computational Biology--methods.

Genetic Techniques.

Genome, Human.

Proteome.

Medical Subjects:

Computational Biology--methods.

Genomics.

Genetic Techniques.

Genome, Human.

Proteome.

Physical Description:

xxv, 753 pages : illustrations (some color) ; 28 cm

Place of Publication:

Hoboken, N.J. : Wiley-Liss, [2003]

Summary:

Bioinformatics and Functional Genomics provides an important integrative approach to understanding both the theory and practice of the emerging field of bioinformatics. Broadly encompassing the field of bioinformatics, from sequence analysis, gene expression, microarrays, and proteomics to molecular phylogenics and whole genome studies, this groundbreaking text shows how bioinformatics applies to biological questions at different levels, such as gene/protein, disease, and protein structures. Combining theoretical context with practical application, the author emphasizes practical skills, such as how to analyze genes and proteins, how to make trees using phylogenic software, how to extract data, and how to identify genes and proteins implicated in disease. Although the text emphasizes the use of computational tools and databases, the author assumes no computational background, making this text an ideal reference for students at every level of study.

Contents:

Access to sequence data and literature information

Pairwise sequence alignment

Basic Local Alignment Search Tool (BLAST)

Advanced BLAST searching

Bioinformatic approaches to gene expression

Gene expression : microarray data analysis

Protein analysis and proteomics

Protein structure

Multiple sequence alignment

Molecular phylogeny and evolution

Completed genomes and the tree of life

Completed genomes : viruses

Completed genomes : bacteria and archaea

Eukaryotic genomes : fungi

Eukaryotic genomes : from parasites to primates

Human genome

Human disease.

Notes:

Includes bibliographical references and indexes.

ISBN:

0471210048

OCLC:

51258266

Online:

Publisher description