Management of infection in oncology patients / editors, John R. Wingard, Raleigh A. Bowden.

Format:

Book

Contributor:

Wingard, John R., 1947-

Bowden, Raleigh A.

Language:

English

Subjects (All):

Infection--Treatment.

Infection.

Cancer--Complications--Treatment.

Cancer.

Cancer--Treatment--Complications.

Neoplasms--complications.

Infections--complications.

Cancer--Complications.

Medical Subjects:

Neoplasms--complications.

Infections--complications.

Physical Description:

xii, 451 pages : illustrations (some color) ; 26 cm

Other Title:

Infection in oncology patients

Place of Publication:

London ; New York : Martin Dunitz ; Independence, KY : Distributed in the USA by Taylor & Francis, 2003.

Summary:

Knowledge of infection management is an essential skill for the effective modern oncologist. Despite major advances in antibacterial, antifungal, and antiviral therapeutics, infection has continued to grow as a problem of medical progress through the last five decades and remains with us today. John Wingard and Raleigh Bowden present a comprehensive review of the range of infectious complications that can arise in oncology patients as a result of their malignancy, as well as from the treatment they are undergoing. This text is practical and informative, and management approaches are detailed for each type of infection and the settings in which they occur.

In the first section, the effects of different treatment strategies on various host defenses are considered. The approaches to solid tumors and hematologic malignancies differ considerably and are dealt with separately. In the second section, the various infectious syndromes in different scenarios are described. Types of pathogens, shifts over time, and changing differential diagnostic considerations are addressed. In the final section, adjunctive measures that can both prevent as well as assist antimicrobial agents in infection control are discussed. The issues posed by transfusion support are also considered in this section. This book is intended to offer practical advice to clinicians and is aimed at practicing oncologists, hematologists, and infectious disease specialists. The authors have provided a comprehensive resource of practical information and a selective list of key references. Where appropriate, gaps in knowledge have been acknowledged and identified as potential research topics.

Contents:

Section I Host Defenses

1. Treatment strategies for solid tumors and impact on host defenses / Margret Merino, Crystal L Mackall 3

2. Treatment strategies for hematological malignancies: Impact on host defenses and infection risk / Ivana Gojo, Clarence B Sarkodee-Adoo, Roger R Hakimian, William G Merz, Judith E Karp 17

3. Blood and marrow transplantation / Leona Holmberg 37

Section II Infectious Syndromes

4. Infectious syndromes in solid tumor therapy / James A Talcott, John R Wingard 55

5. Infectious complications in patients receiving cytotoxic therapy for acute leukemia: History, background and approaches to management / Eric J Bow 71

6. Infections in chronic leukemias and other hematological malignancies / Farhad Ravandi, Elias Anaissie, Susan O'Brien 105

7. Infections in hematopoietic stem cell transplant patients / Elizabeth Reed 129

Section III Management Strategies

8. Infections caused by gram-positive cocci and gram-negative rods / Jacob Strahilevitz, Dan Engelhard 147

9. Management strategies for infections caused by Candida species / Kieren A Marr, Thomas J Walsh 165

10. Invasive aspergillosis complicating neoplastic diseases and hematopoietic stem cell transplantation / Thomas J Walsh, Kieren A Marr 179

11. Fungi other than Candida and Aspergillus / Pranatharthi H Chandrasekar 203

12. Management strategies for herpes simplex viruses in cancer patients and hematopoietic stem cell transplant recipients / Richard J Whitley 223

13. Management strategies for varicella-zoster infections in patients with cancer / Paula W Annunziato, Anne A Gershon 233

14. Management of CMV infection in hematopoietic stem cell transplant recipients / Morgan Hakki, Michael Boeckh 247

15. Epstein-Barr virus infections in the oncology patient / Farid Boulad, Diane George, Trudy N Small, Richard J O'Reilly 269

16. Respiratory viruses in immunocompromised hosts / Laurent Kaiser 287

17. Hepatitis virus infections in patients with cancer / George KK Lau, Simone I Strasser, George B McDonald 321

Section IV Other Therapies

18. Use of hematopoietic growth factors in the management of infection in oncology patients / Dean McGaughey, Jeffrey Crawford 345

19. Granulocyte (neutrophil) transfusion therapy / W Conrad Liles, Kai Hubel, David C Dale 363

20. Uses of immunoglobulins in the management of infection in oncology patients / Helen Leather 373

21. Infection control / Gianna Zuccotti, Kent Sepkowitz 405

22. Vaccinations in oncology patients / Per Ljungman 417

23. Transfusion considerations / Lawrence T Goodnough, John F DiPersio 431.

Notes:

Includes bibliographical references and index.

ISBN:

1901865983

OCLC:

52831010