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Proteases in tissue remodelling of lung and heart / edited by Uwe Lendeckel and Nigel M. Hooper.
Holman Biotech Commons RB140.2 .P76 2003
Available
- Format:
- Book
- Series:
- Proteases in biology and disease ; v. 1.
- Proteases in biology and disease ; v. 1
- Language:
- English
- Subjects (All):
- Tissue remodeling.
- Proteolytic enzymes--Mechanism of action.
- Proteolytic enzymes.
- Lungs--Pathophysiology.
- Lungs.
- Heart--Pathophysiology.
- Heart.
- Peptide Hydrolases.
- Lung--physiopathology.
- Heart--physiopathology.
- Medical Subjects:
- Peptide Hydrolases.
- Lung--physiopathology.
- Heart--physiopathology.
- Physical Description:
- xvi, 237 pages : illustrations ; 24 cm.
- Place of Publication:
- New York : Kluwer Academic/Plenum Publishers, [2003]
- Summary:
- Proteases in Tissue Remodelling of Lung and Heart is unique for its comprehensive presentation of protease function in lung and heart under both physiological conditions and major diseases manifesting in these two organs. The individual chapters have been written by leaders in the field who paid much attention to cover in great detail the role of proteases in the pathogenesis, diagnosis, and treatment of disease. Available animal models (of disease, transgenic, or knock-out) are extensively referred to and experimental data obtained thereby are discussed in the context of patient-derived data. Newcomers to the field and interested non-specialists will take advantage of the extensive introduction to individual proteases, protease families, and the diseases. Understanding is greatly facilitated by the clear and condensed presentation of summarised data in tables and graphs. Thus, the book should be a valuable source for both clinicians and researchers interested in protease function and/or diseases of lung and heart.
- Contents:
- Part I Lung
- Chapter 1 Human leukocyte elastase and cystic fibrosis / Andre M. Cantin, Amelie Fournier, Richard Leduc 1
- Chapter 2 Matrix metalloproteinases in inflammation of the lung / Yves St-Pierre, Celine Van Themsche 35
- Chapter 3 Proteases in interstitial lung diseases / Aline Wille, Tobias Welte, Frank Buhling 57
- Chapter 4 Matrix metalloproteinase inhibitors in cancer therapy / W. Thomas Purcell, Manuel Hidalgo 75
- Chapter 5 The role of proteases in the pathogenesis of lung emphysema / Heiko Golpon, Thomas Kohnlein, Tobias Welte 119
- Part II Heart
- Chapter 6 Cardiac remodeling in pressure overload hypertrophy / Ute Seeland, Michael Bohm 127
- Chapter 7 Ischemia / myocardial infarction The role of matrix metalloproteinases / Tomosaburo Takahashi, Richard T. Lee 139
- Chapter 8 Matrix metalloproteinases and myocardial remodeling in heart failure / Yun You Li, Arthur M. Feldman 157
- Chapter 9 Proteases and arrhythmias / Andreas Goette, Christoph Rocken, Karen Nepple, Uwe Lendeckel 191
- Chapter 10 Impact of proteases in tissue engineering and regeneration / Heike Mertsching, Carmen Puschman 219.
- Notes:
- Includes bibliographical references and index.
- ISBN:
- 0306479109
- OCLC:
- 52943076
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