Bone formation / Felix Bronner and Mary C. Farach-Carson [editors] ; foreword by Gideon A. Rodan.

Format:

Book

Contributor:

Bronner, Felix.

Farach-Carson, Mary C., 1958-

Series:

Topics in bone biology ; v. 1.

Topics in bone biology ; v. 1

Language:

English

Subjects (All):

Bones--Growth.

Bones.

Bones--Growth--Molecular aspects.

Physical Description:

xv, 160 pages : illustrations ; 26 cm.

Place of Publication:

London ; New York : Springer, [2004]

Summary:

Bone research in recent years has generated much new knowledge, in large measure because of the broad public health implications of osteoporosis and related bone disorders. Bone Formation, the first in a series entitled Topics in Bone Biology, evaluates this new information and formulates novel insights and hypotheses within the broad framework of current knowledge. An easy-to handle and to read work, with concise reviews that are extensively referenced, the chapters in this book are written by internationally known authorities. Particular emphasis is on osteoporosis and related disorders of diminished bone formation. Among the general topics treated is a chapter on biomechanical aspects of bone formation, not often considered in relation to diseases of bone formation. The book constitutes essential reading for those entering the field of bone biology and those who wish to become familiar with up-to-date information in a particular area of bone research.

Contents:

1. Molecular Regulation of Osteoblast Differentiation / Prasanna Bukka, Marc D. McKee, Andrew C. Karaplis 1

2. In Vitro Regulation of Osteoblast Activity / Norman J. Karin, Mary C. Farach-Carson 18

3. Systemic and Local Regulators of Bone Remodeling / Marja M. Hurley, Joseph A. Lorenzo 44

4. Site-specific Mineralized Matrix Formation by Osteoblasts / J. Edward Puzas 71

5. Biomechanical Aspects of Bone Formation / Charles H. Turner 79

6. Reduced Bone Formation in the Pathogenesis of Bone Fragility / T. John Martin, Ego Seeman 106

7. Diseases of Excess Bone Formation / William McLean, Bjorn R. Olsen 120

8. Targeting the Osteoblast for Prevention and Treatment of Bone Diseases / Meinrad Peterlik 138.

Notes:

Includes bibliographical references and index.

ISBN:

1852337176

OCLC:

51922855