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The biology of human survival : life and death in extreme environments / Claude A. Piantadosi.

Holman Biotech Commons QP82 .P536 2003
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Format:
Book
Author/Creator:
Piantadosi, Claude A.
Language:
English
Subjects (All):
Extreme environments.
Adaptation (Biology).
Human physiology.
Adaptation, Physiological.
Survival--physiology.
Environment.
Environmental Exposure--adverse effects.
Adaptation, Psychological.
Stress.
Technology--trends.
Medical Subjects:
Adaptation, Physiological.
Survival--physiology.
Environment.
Environmental Exposure--adverse effects.
Adaptation, Psychological.
Stress.
Technology--trends.
Physical Description:
xiv, 263 pages : illustrations, maps ; 24 cm
Place of Publication:
New York : Oxford University Press, 2003.
Contents:
1. The Human Environment 1
The nature of human physical boundaries 1
The importance of preparation for extreme exposures 4
Some basic concepts of survival analysis 5
Characteristics of life-support systems 8
2. Survival and Adaptation 10
The science of human physiology 10
Principles of physiological regulation and adaptation 13
Defining physiological adaptation to the environment 16
Acclimatization and acclimation 18
3. Cross-Acclimation 21
The complexity of adaptation to environment 21
Positive and negative cross-acclimation 22
Biochemical mediators of physiological adaptation 24
Stress proteins and the stress response 25
4. Food for Thought 29
A brief overview of human starvation 29
Starvation: an affliction of the very young and the very old 30
Assessing the severity of starvation 31
Why children die of starvation 33
Other critical factors in human starvation 34
Starvation and obesity: strange bedfellows 36
The molecular basis of obesity and hunger 38
5. Water and Salt 41
The composition of body water 42
Why do human food and water requirements differ? 43
The body's minimum daily water requirements 45
The mechanism of dehydration and the body's responses 47
Dehydration and heat tolerance 49
Survival time without drinking water 51
6. Water That Makes Men Mad 54
The composition of seawater 55
Ingestion of seawater 55
Survival at sea 56
Lessons from the USS Indianapolis 57
A practical approach to salt and water loss at sea 60
7. Tolerance to Heat 63
Mammalian homeothermy 63
Humans as tropical primates 64
Body heat balance 65
Heat acclimatization 70
Heat acclimatization and physical fitness 71
The limitations of human tolerance to heat 72
Heat illnesses 73
Death by heatstroke 76
8. Endless Oceans of Sand 78
The camel and the Berber 79
Desert lessons from Pablo and the Haj 83
Thermal stress and behavior 84
Importance and regulation of heat-escape activities 86
9. Hypothermia 89
The effects of extreme cold on the extremities 89
Settings for systemic hypothermia 90
The physiology of hypothermia 92
Unexpected effects of cold and hypothermia 95
The subtle effect of winter on human mortality 96
10. Life and Death on the Crystal Desert 99
Life in Antarctica 99
The race for the South Pole 100
Failure to adapt to Antarctic conditions 104
Engineering out the need to tolerate cold 106
Human acclimation to cold 107
Estivation 111
Hibernation 112
Hibernation, energy conservation, and suspended animation 117
11. Survival in Cold Water 119
The sinking of the Titanic 119
Water temperature and human survival 121
Prediction of survival time in cold water 121
Survival behavior in cold water 123
Hypothermia in deep sea diving 125
Respiratory heat losses and slow cooling 127
12. Air as Good as We Deserve 129
Life in an oxidizing atmosphere 129
Biological oxidations and oxygen toxicity 132
Antioxidant defenses and the oxidant
antioxidant balance 135
The free radical theory of aging 136
13. Bends and Rapture of the Deep 140
Decompression sickness 141
Rapture of the deep 145
Pressure reversal of anesthesia and the high-pressure nervous syndrome 148
Implications of high pressure for human life on other planets 150
14. Sunken Submarines 152
The sinking of the Kursk 152
The debate over submarine escape 155
The physics of submarine disasters 156
Analysis of survival factors on sunken submarines 158
15. Climbing Higher 164
The physical environment of high altitude 164
Physiological responses to high altitude 166
High-altitude illnesses 173
The zone of death 176
Limits of human ascent to high altitude 179
16. Into the Wild Blue Yonder 181
The International Standard Atmosphere 181
Human visitation to the stratosphere 183
Depressurization accidents 185
The Armstrong line 188
The pressure suit 189
17. G Whiz 193
The continuity principle 193
Gravity and acceleration 194
High-G environments 195
Limits of high-G tolerance 197
Adaptation to sustained G forces 201
18. The Gravity of Microgravity 203
Space sickness 204
Intolerance of upright posture 204
Loss of bone mass in space 206
Loss of muscle mass in space 209
19. Weapons of Mass Destruction 212
Biological and chemical warfare agents 213
Thermonuclear weapons 217
Types of radiation 219
Biological effects of radiation 220
Radiation and the human body 223
20. Human Prospects for Colonizing Space 227
Advanced life-support systems 228
Mission to Mars 230
Habitability factors in long-duration spaceflight 232
Deleterious effects of long-term exposure to microgravity 234
Effects of life in space on human immunity 235
Long-term effects of radiation on human life in space 238
Establishment of permanent human populations in space 242.
Notes:
Includes bibliographical references (pages 247-254) and index.
ISBN:
0195165012
OCLC:
51454527

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