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eClinical trials : planning & implementation / Rebecca Daniels Kush and Paul Bleicher ... [and others].

Holman Biotech Commons R853.C55 K87 2003
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Levy Dental Medicine Library - Stacks R853.C55 K87 2003
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Format:
Book
Author/Creator:
Kush, Rebecca Daniels.
Language:
English
Subjects (All):
Clinical trials.
Drugs--Testing.
Drugs.
Pharmaceutical industry--Technological innovations.
Pharmaceutical industry.
Clinical trials--Data processing.
Clinical Trials as Topic--methods.
Computers.
Information Systems--organization & administration.
Medical Subjects:
Clinical Trials as Topic--methods.
Computers.
Information Systems--organization & administration.
Physical Description:
194 pages : illustrations ; 23 cm
Place of Publication:
Boston, Mass. : Thomson/Centerwatch, [2003]
Contents:
Chapter 2 Today's Clinical Trial 15
The Clinical Research Cycle
Paper-Based 16
The Technology 23
That Can Be Applied Today
Chapter 3 The Optimal Electronic Clinical Trial
A Vision for the Future 36
Goals for the Optimal Electronic Clinical Trial 37
The Vision
Putting It All Together 51
Chapter 4 Process Redesign and Supporting Technologies 54
Shredding the Paper
Process Redesign 55
Metrics for Assessing Newly Introduced Technology 61
Supporting Technologies and Services for eCTs 63
Chapter 5 Achieving eClinical Trials 72
Elements for Implementing eClinical Trials 73
Special Implementation Considerations for eCTs 78
Chapter 6 Measuring and Managing for Success: Metrics for Electronic Clinical Trials 80
Clinical Trials Metrics Collection 81
Chapter 7 Performing Electronic Clinical Trials in Accord with Regulations 91
Agency Aim in Creating 21 CFR 11 92
Regulatory Considerations in Planning an Electronic Clinical Trial 94
Regulatory Considerations While Executing an Electronic Clinical Trial 100
Chapter 8 Data Quality and Data Integrity 108
Error Sources 109
Chapter 9 The Impact of eClinical Trial Technology on Safety Surveillance and IRBs 114
Time Delay 115
Responsibilities for Monitoring Patient Safety 115
Patient Privacy 121
Chapter 10 Industry Data Standards: Ensuring the Success of Electronic Clinical Trial Implementations 124
The Value of Standards 125
The CDISC Operational Data Model 130
Further Progress on Clinical Data Standards 132
Appendix D Traceability Matrix 156
Appendix E 21 CFR Part 11 163
Appendix F Guidance for Industry: Computerized Systems Used in Clinical Trials [CSUCT] 171.
Notes:
Includes bibliographical references (pages 137-138).
ISBN:
193062428X
OCLC:
52854256

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