TNM supplement : a commentary on uniform use / edited by Ch. Wittekind ... [and others].

Format:

Book

Contributor:

Wittekind, Ch. (Christian)

International Union against Cancer.

Language:

English

Subjects (All):

Tumors--Classification.

Tumors.

Neoplasms--classification.

Medical Subjects:

Neoplasms--classification.

Physical Description:

xix, 168 pages : illustrations ; 24 cm

Edition:

Third edition.

Place of Publication:

Hoboken, NJ : Wiley-Liss, [2003]

Summary:

TNM Supplement: A Commentary on Uniform Use, Third Edition updates and expands the International Union Against Cancer's (UICC) monograph defining the proper use of TNM classification for malignant tumours. Internationally, the TNM classification system is the most widely used means to describe the progression of cancer and to indicate prognosis. The UICC's TNM Supplement, as a companion to TNM Classification of Malignant Tumours, Sixth Edition, provides the explanatory notes and definitions that clarify the nuances of the TNM staging system. The TNM Supplement, Third Edition, includes new, detailed definitions of anatomical sites, regional lymph nodes, and TNM categories. It answers questions that often arise during daily use of the TNM system. The text expands on the minimum requirements for pathological classification of individual tumour sites and enumerates the recommended criteria for each. All UICC-sponsored references related to prognostic factors in cancer and the TNM staging system are now available in TNM Online. The online database integrates the full text of TNM Classification of Malignant Tumours, TNM Supplement, and Prognostic Factors in Cancer providing a one-stop resource for all who employ the TNM classification system in assessing the diagnosis, treatment, and prognosis of patients with cancer.

Contents:

The General Rules of the TNM System 1

The TNM Clinical and Pathological Classifications 6

T/pT Classification 6

Regional Lymph Nodes 6

N/pN Classification 7

Sentinel Lymph Node 8

M Classification 9

Who Is Responsible for TNM Coding? 10

The Significance of X 10

Stage Grouping 10

Residual Tumor (R) Classification 12

Additional Descriptors 14

L Classification 15

V Classification 16

Recurrent Tumour, r Symbol 16

Staging of Tumours for Which No TNM Classification Is Provided 16

Histopathological Grading 17

Chapter 2 Explanatory Notes

Specific Anatomical Sites

Head and Neck Tumours 25

Anatomy 25

Extension to Adjacent Sites 25

Regional Lymph Nodes 26

T Classification 30

N Classification 30

Lip and Oral Cavity 30

Pharynx 31

Oropharynx 31

Nasopharynx 32

Hypopharynx 32

Larynx 33

Superior and Inferior Boundaries of the Glottis 33

Pathological Criteria of Impaired Vocal Cord Mobility or Vocal Cord Fixation 34

Associated Carcinoma in situ 34

Nasal Cavity and Paranasal Sinuses 35

Salivary Glands 35

Thyroid 36

Digestive System Tumours 36

Rules for Classification 36

Oesophagus 37

Stomach 38

Anatomy 38

Regional Lymph Nodes 39

T Classification 40

Small Intestine 41

Colon and Rectum 41

Anatomical Sites and Subsites 41

Local Recurrence 42

Regional Lymph Nodes 42

T/pT Classification 42

N/pN Classification 43

M Classification 44

Anal Canal 44

Rules for Classification 44

T Classification 44

Liver 44

Regional Lymph Nodes 44

T/pT Classification 45

Gallbladder 45

Extrahepatic Bile Ducts 46

Anatomical Subsites 46

Ampulla of Vater 46

Pancreas 47

T Classification 47

Regional Lymph Nodes 47

Lung 47

Rules for classification 47

T Classification 48

M Classification 49

Small Cell Carcinoma 49

Pleural Mesothelioma 49

Bone Tumours 50

Soft Tissue Tumours 51

Skin Tumours 51

Carcinoma of Skin 51

Malignant Melanoma of Skin 52

Rules for Classification 52

pT Classification of Malignant Melanoma 53

N Classification 53

Breast Tumours 53

Rules for Classification 55

Regional Lymph Nodes 55

T Classification 55

N/pN Classification 56

Gynaecological Tumours 56

Vulva 56

Vagina 57

Cervix Uteri 58

Corpus Uteri 59

Grading 59

Ovary 60

N Classification 61

M Classification 61

Fallopian Tube 61

Gestational Trophoblastic Tumours 61

Urological Tumours 63

Penis 63

Prostate 64

T Classification 64

Testis 65

Kidney 66

Renal Pelvis and Ureter 67

Urinary Bladder 67

Recurrent Carcinoma after Cystectomy and Ureterosigmoidostomy 68

Urethra 69

Ophthalmic Tumours 70

Carcinoma of Eyelid 70

Carcinoma of Conjunctiva 70

Malignant Melanoma of Conjunctiva 71

Uvea Malignant Melanoma 71

Hodgkin and Non-Hodgkin Lymphomas 72

Chapter 3 Site-Specific Recommendations for pT and pN

Head and Neck Tumours 89

Thyroid Gland 92

Lung and Pleural Tumours 97

Tumours of Bone and Soft Tissues 99

Skin Tumours 100

Breast Tumours 101

Gynaecological Tumours 104

Urological Tumours 106

Ophthalmic Tumours 110

pT

Primary Tumour 110

pN

Regional Lymph Nodes 111

Hodgkin Lymphoma and Non-Hodgkin Lymphoma 112

Chapter 4 New TNM Classifications Recommended for Testing

Perineural Invasion 115

Pn

Perineural invasion 116

Specific 116

Gastrointestinal Sarcomas 116

Malignant Thymoma 118

Cranial and Facial Bones 120

Cutaneous T-Cell Lymphoma (Excluding Lip, Eyelid, Vulva and Penis) 123

Chronic Myeloid Leukaemia 126

Primary Liver Carcinoma in Infants and Children 128

Adrenal Cortical Carcinoma 130

Liver Metastasis of Colorectal Carcinoma 131

Gastrointestinal Malignant Lymphomas 132

Chapter 5 Optional Proposals for Testing New Telescopic Ramifications of TNM

All Tumour Sites 138

Fixation of Lymph Nodes 138

Markers of Residual Tumour 138

Head and Neck Tumours 138

Thyroid Gland 138

T Classification 138

Digestive System Tumours 139

M Classification 139

Oesophagus 139

T Classification 139

N Classification 139

Stomach 140

T Classification 140

N Classification 140

Colon and Rectum 141

pT Classification 141

Liver 143

N Classification 143

Lung Tumours 143

M Classification 143

Stage Grouping of Lung Tumours 143

Tumours of Bone and Soft Tissues 144

Bone 144

T Classification 144

Skin Tumours 144

Carcinoma of Skin 144

Gynaecological Tumours 145

Cervix Uteri 145

N Classification 145

M Classification 145

Urological Tumours 145

Penis 146

T Classification 146

Prostate 146

M Classification 146

Kidney 146

Chapter 6 Frequently Asked Questions

In Situ Carcinoma 151

Clinical and Pathological Stage 151

R Classification 151

R Classification and Tis 152

Positive Cytology 152

T0 and TX 153

Synchronous Tumours 153

Single Tumour Cells and Micrometastasis in Lymph Nodes 153

Number of Lymph Nodes 154

Pathological Assessment of Distant Metastasis 154

Classification of Brain Tumours 154

Classification of Primary Peritoneal Neoplasms 155

Pathological versus Clinical TNM 155

When in Doubt 156

Tumor Cells in Lymphatics 156

Tumor Spillage 156

Simultaneous Tumors 156

Direct Spread 157

Nversus M 157

Unknown Primary 158

AJCC versus UICC TNM 158

Sentinel Lymph Node 158

Site Specific Questions 159

Larynx 159

Oesophagus 159

Colon and Rectum 160

Lung 161

Breast 162

Corpus uteri 165

Ovary versus Uterus 165

Ovary 166

Prostate 166

Kidney 166

Bladder 167.

Notes:

At head of title: UICC International Union against Cancer.

"... a companion to TNM classification of malignant tumours, sixth edition ... "--P. [4] of cover.

Includes bibliographical references.

ISBN:

0471466662

OCLC:

51937288