Micrometastasis / edited by Klaus Pantel.

Format:

Book

Contributor:

Pantel, Klaus.

Series:

Cancer metastasis (Series) ; v. 5.

Cancer metastasis ; v. 5

Language:

English

Subjects (All):

Metastasis.

Metastasis--Diagnosis.

Metastasis--Molecular aspects.

Neoplasm Metastasis--physiopathology.

Molecular Diagnostic Techniques.

Diagnosis.

Medical Subjects:

Neoplasm Metastasis--physiopathology.

Molecular Diagnostic Techniques.

Physical Description:

x, 189 pages : illustrations ; 25 cm.

Place of Publication:

Dordrecht ; Boston : Kluwer Academic Publishers, [2003]

Summary:

Distant metastases are the main cause of cancer-related death. The onset of the metastatic process can now be assessed in cancer patients by the use of immunocytochemical and molecular methods that allow the identification of disseminated carcinoma cells in regional lymph nodes, peripheral blood, or distant organs. There is increasing evidence that the detection and characterization of tumor cells present in bone marrow or peripheral blood can provide clinically important information. In this book, leading experts in the area of micrometastasis research provide an overview that summarizes the current state of research on micrometastatic disease in patients with solid tumors. In each chapter, the technical aspect as well as clinical relevance of micrometastasis detection is discussed. The book addresses basic researchers as well as clinicians involved in the treatment of cancer patients.

Contents:

Chapter 1 Technical Aspects of the Detection of Disseminated Tumour Cells by Molecular Methods / William H. Kruger 1

Chapter 2 RNA/DNA Based Detection of Minimal Residual Head and Neck Cancer / Ruud H. Brakenhoff 19

Chapter 3 Detection and Characterisation of Occult Metastatic Cells in Bone Marrow of Breast Cancer Patients: Implications for Adjuvant Therapy / Stephan Braun, Volkmar Muller, Klaus Pantel 47

Chapter 4 Prognosis of Minimal Residual Disease in Bone Marrow, Blood and Lymph Nodes in Breast Cancer / Debra Hawes, A. Munro Neville, Richard J. Cote 67

Chapter 5 Detection, Isolation and Study of Disseminated Prostate Cancer Cells in the Peripheral Blood and Bone Marrow / Jesco Pfitzenmaier, Robert L. Vessella, William J. Ellis, Paul H. Lange 87

Chapter 6 Early Disseminated Tumour Cells in Operable Non-Small Cell Lung Cancer / Bernward Passlick 117

Chapter 7 Prognostic Value of Minimal Residual Disease in Esophageal Cancer / Peter Scheuemann, Stefan B. Hosch, Jacob R. Izbicki 127

Chapter 8 Clinical Relevance of Tumor Cell Dissemination in Colorectal, Gastric and Pancreatic Carcinoma / Ilka Vogel, Holger Kalthoff 139

Chapter 9 Minimal Residual Disease in Melanoma / Petra Goldin-Lang, Ulrich Keilholz 173.

Notes:

Includes bibliographical references and index.

ISBN:

1402011555

OCLC:

51447332