Essentials of pathophysiology : concepts of altered health states / Carol Mattson Porth ; consultant, Kathryn J. Gaspard.

Format:

Book

Author/Creator:

Porth, Carol.

Contributor:

Porth, Carol.

Language:

English

Subjects (All):

Physiology, Pathological.

Disease.

Pathology.

Physiology.

Medical Subjects:

Disease.

Pathology.

Physiology.

Physical Description:

xxii, 915 pages : color illustrations ; 28 cm + 1 CD-ROM (sound, color ; 4 3/4 in.)

Place of Publication:

Philadelphia ; London : Lippincott Williams & Wilkins, [2004]

System Details:

System requirements for accompanying CD-ROM: Windows 98 SE, NT 4.0, ME, or XP; Pentium 300 MHz or faster processor; 64 MB RAM (128 MB recommended); 16X CD-ROM drive; 800 x 600, 32-bit (True Color) resolution monitor; Windows-compatible sound card; Internet Explorer 3.0 or later; 10 MB of free disk space.

text file

Summary:

Looking for a text that delivers concept-based information about disease processes and altered health states? Essentials of Pathophysiology is the right text for you! Written by a noted expert in pathophysiology, this abundantly illustrated and accessible resource is filled with learning tools that highlight the ideas most vital to your understanding. Consistent with the author's philosophy, Essentials of Pathophysiology relates normal body functioning to the physiologic changes involved in pathogenesis and those that result from disease.

Contents:

Unit 1 Mechanisms of Disease

1 Cell Structure and Function / Edward W. Carroll 1

Functional Components of the Cell 2

Cell Metabolism and Energy Sources 7

Cell Membrane Transport, Signal Transduction, and Generation of Membrane Potentials 9

Body Tissues 14

2 Tissue Adaptation and Injury 24

Cellular Adaptation 24

Cell Injury and Death 27

3 Genetic Control of Cell Function / Edward W. Carroll 36

Genetic Control of Cell Function 36

Chromosomes 41

Patterns of Inheritance 44

Gene Mapping and Technology 46

4 Genetic and Congenital Disorders 50

Genetic and Chromosomal Disorders 50

Disorders Due to Environmental Influences 58

5 Alterations in Cell Growth and Replication: Neoplasia / Kathryn Ann Caudell 64

Concepts of Cell Growth 64

Characteristics of Benign and Malignant Neoplasms 67

Carcinogenesis and Causes of Cancer 72

Clinical Features 77

Childhood Cancers 81

6 Alterations in Fluids, Electrolytes, and Acid-Base Balance 84

Composition and Compartmental Distribution of Body Fluids 84

Sodium and Water Balance 90

Potassium Balance 99

Calcium and Magnesium Balance 103

Acid-Base Balance 108

Unit 2 Alterations in Body Defenses

7 Stress and Adaptation / Mary Pat Kunert 121

Homeostasis 122

Stress 123

Disorders of the Stress Response 128

8 The Immune Response / Cynthia V. Sommer 134

The Immune System 134

Developmental Aspects of the Immune System 148

9 Inflammation, Tissue Repair, and Fever / Cynthia V. Sommer, Carol M. Porth 150

The Inflammatory Response 150

Tissue Repair and Wound Healing 157

Temperature Regulation and Fever 161

10 Alterations in the Immune Response / Carol M. Porth, Kathleen Sweeney 168

Allergic and Hypersensitivity Disorders 168

Transplantation Immunopathology 174

Autoimmune Disorders 175

Immunodeficiency Disorders 178

Unit 3 Alterations in the Hematologic System

11 Alterations in White Blood Cells / Kathryn Ann Caudell, Kathryn J. Gaspard 191

Hematopoietic and Lymphoid Tissue 191

Non-neoplastic Disorders of White Blood Cells 194

Neoplastic Disorders of Hematopoietic and Lymphoid Origin 197

12 Alterations in Hemostasis and Blood Coagulation / Kathryn J. Gaspard 205

Mechanisms of Hemostasis 205

Hypercoagulability States 209

Bleeding Disorders 210

13 Alterations in Red Blood Cells / Kathryn J. Gaspard 216

The Red Blood Cell 216

Anemia 220

Polycythemia 227

Age-Related Changes in Red Blood Cells 227

Unit 4 Alterations in the Cardiovascular System

14 Structure and Function of the Cardiovascular System 231

Organization of the Circulatory System 232

Principles of Blood Flow 233

The Heart as a Pump 236

Blood Vessels and the Peripheral Circulation 246

Neural Control of Circulatory Function 251

15 Alterations in Blood Flow 254

Disorders of the Arterial Circulation 254

Disorders of the Venous Circulation 266

Disorders of Blood Flow Caused by Extravascular Forces 269

16 Alterations in Blood Pressure 274

Control of Blood Pressure 274

Hypertension 279

Orthostatic Hypotension 287

17 Alterations in Cardiac Function 291

Disorders of the Pericardium 291

Coronary Heart Disease 294

Myocardial and Endocardial Disease 302

Valvular Heart Disease 308

Heart Disease in Infants and Children 312

18 Heart Failure and Circulatory Shock / Candace Hennessy, Carol M. Porth 320

Circulatory Failure (Shock) 330

Heart Failure in Children and the Elderly 336

Unit 5 Alterations in the Respiratory System

19 Structure and Function of the Respiratory System 339

Structural Organization of the Respiratory System 340

Exchange of Gases Between the Atmosphere and the Lungs 344

Exchange and Transport of Gases 351

Control of Breathing 356

20 Alterations in Respiratory Function: Infectious Disorders and Neoplasia 359

Respiratory Tract Infections 359

Cancer of the Lung 367

Respiratory Disorders in Infants and Children 369

21 Alterations in Respiratory Function: Disorders of Gas Exchange 376

Disorders of Lung Inflation 376

Obstructive Airway Disorders 380

Interstitial Lung Diseases 390

Pulmonary Vascular Disorders 392

Respiratory Failure 395

Unit 6 Alterations in the Urinary System

22 Control of Kidney Function 401

Kidney Structure and Function 402

Tests of Renal Function 412

23 Alterations in Renal Function 415

Congenital and Hereditary Disorders of the Kidney 415

Obstructive Disorders 417

Urinary Tract Infections 421

Disorders of Glomerular Function 425

Tubulointerstitial Disorders 429

Neoplasms 430

24 Renal Failure 433

Acute Renal Failure 433

Chronic Renal Failure 436

Renal Failure in Children and Elderly Persons 443

25 Alterations in Urine Elimination 446

Control of Urine Elimination 446

Alterations in Bladder Function 449

Cancer of the Bladder 456

Unit 7 Alterations in the Gastrointestinal System

Structure and Organization of the Gastrointestinal Tract 460

Innervation and Motility 463

Hormonal and Secretory Function 466

Digestion and Absorption 468

Anorexia, Nausea, and Vomiting 471

27 Alterations in Gastrointestinal Function 473

Disorders of the Esophagus 473

Disorders of the Stomach 476

Disorders of the Small and Large Intestines 480

28 Alterations in Hepatobiliary Function 494

The Liver and Hepatobiliary System 494

Disorders of the Liver 500

Disorders of the Gallbladder and Extrahepatic Bile Ducts 510

Disorders of the Exocrine Pancreas 513

29 Alterations in Body Nutrition / Joan Pleuss 517

Regulation of Food Intake and Energy Metabolism 517

Overnutrition and Obesity 521

Undernutrition 524

Unit 8 Alterations in the Endocrine System

30 Organization and Control of the Endocrine System / Glenn Matfin, Safak Guven, Julie A. Kuenzi 529

31 Alterations in Pituitary, Thyroid, Parathyroid, and Adrenal Function / Glenn Matfin, Safak Guven, Julie A. Kuenzi 538

General Aspects of Altered Endocrine Function 538

Pituitary and Growth Hormone Disorders 539

Thyroid Disorders 545

Parathyroid Hormone Disorders 551

Disorders of Adrenal Cortical Function 552

32 Diabetes Mellitus / Safak Guven, Julie A. Kuenzi, Glenn Matfin 560

Energy Metabolism 560

Unit 9 Alterations in the Male and Female Reproductive Systems

Physiologic Basis of Male Reproductive Function 581

Disorders of the Penis, the Scrotum and Testes, and the Prostate 587

Disorders in Childhood and Aging Changes 597

34 Alterations in the Female Reproductive System / Patricia McCowen Mehring 602

Structure and Function of the Female Reproductive System 602

Disorders of the Female Reproductive Organs 607

Menstrual Disorders 619

Disorders of the Breast 622

35 Sexually Transmitted Diseases / Patricia McCowen Mehring 627

Infections of the External Genitalia 627

Vaginal Infections 630

Vaginal-Urogenital-Systemic Infections 632

Unit 10 Alterations in the Nervous System

36 Organization and Control of the Nervous System / Edward W. Carroll, Robin L. Curtis 637

Nervous Tissue Cells 637

Nerve Cell Communication 641

Development and Organization of the Nervous System 644

The Spinal Cord and Brain 651

The Autonomic Nervous System 660

37 Alterations in Brain Function / Diane Book 667

Brain Injury 668

Cerebrovascular Disease 679

Infections and Neoplasms 685

Seizure Disorders 688

Dementias 691

38 Alterations in Neuromuscular Function / Carol M. Porth, Robin L. Curtis 696

The Organization and Control of Motor Function 696

Skeletal Muscle and Peripheral Nerve Disorders 702

Basal Ganglia and Cerebellum Disorders 709

Upper and Lower Motoneuron Disorders 713

Spinal Cord Injury 716

39 Pain / Elizabeth C.

Devine 725

Organization and Control of Somatosensory Function 725

Pain 731

Alterations in Pain Sensitivity and Special Types of Pain 739

Headache 741

Pain in Children and Older Adults 744

40 Alterations in Special Sensory Function / Edward W. Carroll, Susan A. Fontana 747

The Eye and Disorders of Vision 747

The Ear and Disorders of Auditory Function 763

The Vestibular System and Maintenance of Equilibrium 772

Unit 11 Alterations in the Skeletal and Integumentary Systems

41 Structure and Function of the Skeletal System 779

Characteristics of Skeletal Tissue 779

Skeletal Structures 785

42 Alterations in the Skeletal System: Trauma, Infection, and Developmental Disorders / Kathleen E. Gunta 789

Injury and Trauma of Musculoskeletal Structures 789

Bone Infections 799

Neoplasms 802

Disorders of Skeletal Growth and Development in Children 805

43 Alterations in the Skeletal System: Metabolic and Rheumatoid Disorders / Debra Bancroft Rizzo, Kathleen E. Gunta 814

Metabolic Bone Disease 814

Rheumatic Disorders 820

Rheumatic Diseases in Children and the Elderly 832

44 Alterations in Skin Function and Integrity / Gladys Simandl 835

Structure of the Skin 835

Manifestations of Skin Disorders 839

Skin Damage Caused by Ultraviolet Radiation 841

Primary Disorders of the Skin 842

Nevi and Skin Cancers 853

Age-Related Skin Manifestations 857.

Notes:

Abridgement of: Pathophysiology / Carol Mattson Porth. 6th ed. 2002.

Includes bibliographical references and index.

Related Work:

Porth, Carol. Pathophysiology.

ISBN:

0781746450

OCLC:

51944392