Dementia : a clinical approach / Mario F. Mendez, Jeffrey L. Cummings.

Format:

Book

Author/Creator:

Mendez, Mario F.

Contributor:

Cummings, Jeffrey L., 1948-

Language:

English

Subjects (All):

Dementia.

Medical Subjects:

Dementia.

Physical Description:

xxiii, 654 pages, 10 unnumbered pages of plates : illustrations (some color) ; 24 cm

Edition:

Third edition.

Place of Publication:

Philadelphia : Butterworth-Heinemann, [2003]

Summary:

Here is all of the very latest scientific and clinical information for every type for dementing disease -- presented in a handy, easy-to-read format. Noted specialists in the field equip readers with the guidance they need to understand, diagnose, and manage these conditions using all of the best approaches available today. They emphasize a neurologic investigative approach to differentiate the curable from the noncurable dementias. Disorders are organized into cortical and subcortical dementias to emphasize the different clinical features that facilitate diagnosis.

Contents:

1. Dementia: Significance, Definition, and Epidemiology 1

Prevalence of Different Dementing Diseases 7

2. Mental Status Assessment 13

Clinical History 16

Mental Status Examination 19

Behavioral Rating Scales 34

Standardized Neuropsychological Tests 36

3. Diagnosis of Dementia 41

Normal Aging versus Dementia 41

Age-Associated Cognitive Impairments 43

Mild Cognitive Impairment 44

Amnesia versus Dementia 45

Delirium versus Dementia 46

Aphasia versus Dementia 50

Differential Diagnosis of Dementing Diseases 51

Examples of Differential Diagnosis 59

4. Alzheimer's Disease 67

Clinical Characteristics 68

Disease Course 76

Laboratory Investigation 78

Neuropathology 82

Risk Factors and Etiology 87

Proposed Pathophysiologic Mechanisms 94

Prevention and Treatment 95

5. Vascular Dementia 121

Clinical Criteria for Vascular Dementia 123

Classification and Characteristics of Vascular Dementia 125

Differential Diagnosis 147

Disease Course 149

Laboratory Investigation 149

Pathology and Pathophysiology 151

Risk Factors 153

Treatment 156

6. Frontotemporal Dementia and the Asymmetric Cortical Atrophies 179

Frontotemporal Lobar Degeneration 179

Frontotemporal Dementia 180

Asymmetric Cortical Atrophies 201

7. Parkinsonian Disorders with Dementia 235

Dementia with Lewy Bodies 236

Parkinson's Disease with Dementia 243

Progressive Supranuclear Palsy 252

Corticobasal Degeneration 256

Multiple System Atrophy 260

Heredodegenerative Diseases with Parkinsonism 263

Secondary Parkinsonism 264

8. Nonparkinsonian Motor Disorders with Dementia 291

Huntington's Disease 291

Wilson's Disease 301

Hallervorden-Spatz Disease 307

Amyotrophic Lateral Sclerosis/Parkinson's Dementia Complex 310

Motor Neuron Disease with Dementia 312

Hereditary Spinocerebellar Ataxias 316

Dementia with Other Motor Disorders 321

9. Dementia from Conventional Infectious Agents 339

HIV-Associated Dementia 339

Neurosyphilis 350

Lyme Disease 357

Whipple's Disease 358

Non-HIV Causes of Viral Encephalitis 360

Other Bacterial and Fungal Causes of Meningitis 366

Parasitic Diseases 368

10. Creutzfeldt-Jakob Disease and Other Prion Disorders 387

Creutzfeldt-Jakob Disease 388

Other Prion Dementias 407

11. Toxic-Metabolic Causes of Dementia 421

Toxic Dementias 421

Acquired Metabolic Disorders 434

Inherited Metabolic Disorders 446

12. Psychiatric Dementias Associated with Psychiatric Disorders 477

Depression-Associated Dementia 478

Mania-Associated Dementia 485

Schizophrenia-Associated Dementia 488

"Pseudodementia" 492

13. Miscellaneous Dementia Syndromes 503

Normal Pressure Hydrocephalus 503

Trauma and Dementia Pugilistica 513

Neoplasia-Related Dementia 521

Multiple Sclerosis 527

Epilepsy 531

Miscellaneous Unclassified Dementias 534

14. Pharmacotherapy of Alzheimer's Disease and Other Dementias 559

Cholinergic Agents 560

Antioxidants 564

Other Cognitive Agents 564

Herbal Remedies 567

Summary of Cognitive Pharmacotherapy for Alzheimer's Disease 569

Psychoactive Medications 570

15. Nonpharmacologic Management of Dementia 583

Diagnostic Interaction 588

Family Instruction 589

Caregiver Support 590

Psychosocial Issues 594

Advanced Dementia Care 596

Special Issues 600

Concepts and Attitudes About Dementia 605

Demographic Projections 606

Prevention and Early Detection 606

Biological Markers 607

Pharmacotherapy 608

Future Strategies 610.

Notes:

Rev. ed. of: Dementia / Jeffrey L. Cummings, D. Frank Benson. 2nd ed. c1992.

Includes bibliographical references and index.

Related Work:

Cummings, Jeffrey L., 1948- Dementia.

ISBN:

0750674709

OCLC:

51582228