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The microbial models of molecular biology : from genes to genomes / Rowland H. Davis.
Holman Biotech Commons QH506 .D395 2003
Available
Levy Dental Medicine Library - Stacks QH506 .D395 2003
Available
LIBRA QH506 .D395 2003
Available from offsite location
- Format:
- Book
- Author/Creator:
- Davis, Rowland H.
- Language:
- English
- Subjects (All):
- Molecular biology--History.
- Molecular biology.
- Molecular genetics--History.
- Molecular genetics.
- Microbial genetics--History.
- Microbial genetics.
- Molecular microbiology--History.
- Molecular microbiology.
- Genetics, Microbial--history.
- Models, Biological.
- Molecular Biology--history.
- History, 20th Century.
- History.
- Medical Subjects:
- Genetics, Microbial--history.
- Models, Biological.
- Molecular Biology--history.
- History, 20th Century.
- Physical Description:
- xiv, 337 pages : illustrations ; 25 cm
- Place of Publication:
- New York : Oxford University Press, 2003.
- Summary:
- This book explains the role of simple biological model systems in the growth of molecular biology. Essentially the whole history of molecular biology is presented here, tracing the work in bacteriophages in E. coli, the role of other prokaryotic systems, and also the protozoan and algal models - Paramecium and Chlamydomonas, primarily - and the move into eukaryotes with the fungal systems - Neurospora, Aspergillus and yeast. Each model was selected for its appropriateness for asking a given class of questions, and each spawned its own community of investigators. Some individuals made the transition to a new model over time, and remnant communities of investigators continue to pursue questions in all these models, as the cutting edge of molecular biological research flowed onward from model to model, and onward into higher organisms and, ultimately, mouse and man.
- Contents:
- Model systems, model organisms
- Morgan's progeny
- Neurospora
- Aspergillus
- Yeast
- Leaving the fungi
- Escherichia coli
- The T bacteriophages
- Temperate phages and transduction
- DNA
- Prokaryotes take center stage
- Prokaryotes : later contributions
- Cytoplasmic inheritance : the ciliates
- Organelle genetics : yeast and chlamydomonas
- Yeast becomes a supermodel
- The filamentous fungi : eclipse and renewal
- The role of biochemistry
- Genomics
- The age of model organisms.
- Notes:
- Includes bibliographical references (pages 303-322) and indexes.
- ISBN:
- 0195154363
- OCLC:
- 50859614
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