Diagnosis and control of Johne's disease / Committee on Diagnosis and Control of Johne's Disease, Board on Agriculture and Natural Resources, Division of Earth and Life Sciences, National Research Council of the National Academies.

Format:

Book

Contributor:

National Research Council (U.S.). Committee on Diagnosis and Control of Johne's Disease.

Language:

English

Subjects (All):

Paratuberculosis--Diagnosis.

Paratuberculosis.

Paratuberculosis--Treatment.

Diagnosis.

Physical Description:

xiv, 229 pages : illustrations ; 23 cm

Other Title:

Johne's disease

Place of Publication:

Washington, D.C. : National Academies Press, [2003]

Summary:

Johne's Disease is a chronic, progressive intestinal disease caused by infection with Mycobacterium avium subspecies paratuberculosis (Map) that affects primarily ruminant animals. In recent decades there has been growing concern over the lack of effective control of this disease and questions have arisen regarding the possibility that Map infection could be a cause of some cases of Crohn's disease in humans. This report presents a broad outline of the steps that should be taken to control Johne's disease, reduce the spread of Map, and minimize effects of the disease in animals. The report also describes the weaknesses of our current research agenda and provides recommendations for a new research strategy to resolve the question of whether there is a link between Johne's and Crohn's diseases.

Contents:

The Task 2

Disease Control 4

Education and Training 7

Research 7

The Committee's Task 15

2 Johne's Disease in Domesticated and Wild Animals 16

Spectrum of Disease in Domesticated Animals 18

Spectrum of Disease in Other Animals 20

Pathology 21

Epidemiology 24

Modes of Transmission 27

Pathogenesis in Cattle 37

3 Diagnostics 45

Testing of Domesticated Animals 45

Molecular Methods 59

Epidemiologic Tools 62

4 Control Principles and Programs 66

Control Principles 66

Current Control Programs 78

Principles of Control Implementation 97

5 Economic Implications of Johne's Disease 99

Trade 100

6 Johne's Disease and Crohn's Disease 104

Crohn's Disease 105

Implications of the Link 107

Control Programs 122

Education and Training Recommendations 126

Research Recommendations 127

A Interpretation of Diagnostic Results 175

B USAHA Voluntary Johne's Disease Herd Status Program for Cattle 179

C USDA/APHIS Draft Johne's Disease Control Program 194.

Notes:

Includes bibliographical references (pages 133-174).

ISBN:

0309086116

OCLC:

53043179