Protein secretion pathways in bacteria / edited by Bauke Oudega.

Format:

Book

Contributor:

Oudega, Bauke.

Language:

English

Subjects (All):

Microbial metabolism.

Proteins--Secretion.

Proteins.

Bacterial Proteins--metabolism.

Medical Subjects:

Bacterial Proteins--metabolism.

Physical Description:

vii, 296 pages : illustrations ; 25 cm

Place of Publication:

Dordrecht ; Boston : Kluwer Academic, [2003]

Summary:

For bacteria .. "the times are achanging" ... The genomes of over 60 different bacteria have now been sequenced, and we know a lot about the important research organism Escherichia coli, the important industrial organism Bacillus subtilis, and about important plant and human pathogens. It will not take long before we know all the gene products and the functions of a few of these bacteria. Some of us already begin to think about a digital model E. coli or Bacillus cell. For that end we need to know all the physiological activities and metabolic routes of the cell. But in addition we like to know how things work at the molecular level and how protein and membranes as well as other (macromolecular) structures work together to carry out specific cell functions. Protein Secretion Pathways in Bacteria describes all the known folding and targeting routes of inner and outer membrane proteins as well as of proteins that are secreted by several specific export routes. The book gives detailed molecular information about the structures that are important for the different mechanisms involved. This is a valuable contribution to the understanding of how rather simple and yet complex bacterial cells work.

Contents:

1. Protein Targeting to the Inner Membrane / Joen Luirink, Bauke Oudega 1

2. The SEC Translocase / Chris van den Does, Nico Nouwen, Arnold J.M. Driessen 23

3. The TAT Protein Export Pathway / Tracy Palmer, Ben C. Berks 51

4. Assembly of Inner Membrane Proteins in Escherichia coli / David Drew, Linda Froderberg, Louise Baars, Joen Luirink, Jan-Willem de Gier 65

5. Biogenesis of Outer Membrane Proteins / Jan Tommassen, Rome Voulhoux 83

6. Chaperones and Folding Catalysts Involved in the General Protein Secretion Pathway of Escherichia coli / Nellie Harms, Hans de Cock 99

7. Type I Protein Secretion Systems in Gram-Negative Bacteria: Escherichia coli [alpha]-Hemolysin Secretion / Ivaylo Gentschev, Werner Goebel 121

8. Type II Protein Secretion / Alain Filloux, Manon Gerard-Vincent 141

9. The Type III Secretion Pathway in Pathogenic Bacteria / Claude Parsot 167

10. Autotransporters / Ben R. Otto 191

11. Assembly of Adhesive Organelles on Gram-Negative Bacteria / Sheryl S. Justice, Karen W. Dodson, Matthew R. Chapman, Michelle M. Barnhart, Scott J. Hultgren 207

12. Export of Bacteriocins / Bauke Oudega 233

13. Biogenesis of Flagella: Export of Flagellar Proteins via the Flagellar Machine / Tohru Minamino, Shin-Ichi Aizawa 249

14. Protein Secretion in Gram-Positive Bacteria / Rob Meima, Jan Maarten van Dijl 271.

Notes:

Includes bibliographical references.

ISBN:

1402012551

OCLC:

52001697