Advances in prostaglandin, leukotriene, and other bioactive lipid research : basic science and clinical applications / edited by Zeliha Yazici ... [and others].

Format:

Book

Conference/Event

Contributor:

Yazici, Zelina.

Conference Name:

International Conference on Advances in Prostaglandin, Leukotriene, and Other Bioactive Lipid Research (12th : 2002 : Istanbul, Turkey)

Series:

Advances in experimental medicine and biology ; v. 525.

Advances in experimental medicine and biology

Language:

English

Subjects (All):

Prostaglandins.

Leukotrienes.

Prostaglandins--Congresses.

Leukotrienes--Congresses.

Inflammation--Mediators--Congresses.

Inflammation.

Inflammation--Mediators.

Cellular signal transduction--Congresses.

Cellular signal transduction.

Cytochrome P-450--Congresses.

Cytochrome P-450.

Medical Subjects:

Prostaglandins.

Leukotrienes.

Genre:

Conference papers and proceedings.

Physical Description:

xxvi, 226 pages : illustrations ; 26 cm.

Other Title:

Prostaglandin, leukotriene, and other bioactive lipid research

Place of Publication:

New York : Kluwer Academic/Plenum Publishers, [2003]

Summary:

This volume, the Proceedings of the 12th InternationalConference on Advances in Prostaglandin, Leukotriene and OtherBioactive Lipid Research: Basic Science and Clinical Applications, held August 25-29, 2002, in Istanbul, Turkey, discusses advances inbioactive lipid research with special attention to cancer, cardiovascular diseases, gastrointestinal diseases and respiratorydiseases. Specific topics covered include the role of leukotrienes andlipoxins in inflammation, the cytochrome P450 pathway, the geneticsand genomics of bioactive lipids, lipid peroxidation, apoptosis, angiogenesis, isoprostanes, receptors and inhibitors, cyclooxygenaseand lipoxygenase pathways and inhibitors, prostaglandin synthases andreceptor signaling, phospholipases and inhibitors.

Contents:

Leukotrienes and Lipoxins: Inflammation and Asthma

1. Leukotrienes in Asthma / J.M. Drazen 1

2. Leukotriene Receptors: State of the Art / C. Brink 7

3. LTC[subscript 4] Production by Eosinophils in Asthmatic Subjects with Alternative Forms of Alox-5 Core Promoter / O. Kalayci, M. Wechsler, B. Galper, C. Hong, E. Israel, J.M. Drazen, C.M. Lilly 11

4. Il-4-Induced Lipid Mediators Class Switching in Human Normal Mononuclear Phagocytes / A. Sala, M. Profita, L. Siena, P.M. Henson, R..C. Murphy, A. Paterno, A. Bonanno, L. Riccobono, A. Mirabella, G. Bonsignore, A.M. Vignola 15

5. Lipoxins and Aspirin-Triggered Lipoxins in Airway Responses / B.D. Levy, G.T. Desanctis, P.R. Devchand, E. Kim, K. Ackerman, B. Schmidt, W. Szczeklik, J.M. Drazen, C.N. Serhan 19

6. Potential Role of Cysteinyl Leukotrienes in Trafficking and Survival of Hematopoietic Progenitor Cells / A.M. Boehmler, C. Denzlinger, L. Kanz, R. Mohle 25

7. Covalent Binding of Leukotriene A[subscript 4] to Nucleosides, Nucleotides, and Nucleic Acids / J.A. Hankin, R.C. Murphy 29

8. Firm Adhesion of Neutrophils to Cerebral Vascular Endothelium "In Vivo": A Role for Cys-Leukotrienes / C. Carnini, G. Constantin, B. Rossi, M. De Curtis, G. Folco 35

Cytochrome P450 Pathway

9. The CYP P450 Arachidonate Monooxygenases: Enzymatic Relays for the control of Kidney Function and Blood Pressure / J.H. Capdevila, K. Nakagawa, V. Holla 39

10. Cytochrome P450-Derived Eicosanoids are Mediators of Ocular Surface Inflammation / M.L. Schwartzman, M.W. Dunn 47

11. Regulation of Renal Microvascular 20-Hydroxyeicosatetraenoic Acid (20-Hete) Levels / M.A. Carroll, M.K. Cheng, H. Jiang, A.B. Doumad, M.F. Capparelli, J.C. McGiff 55

12. Cyclooxygenase Activity is Regulated by the Heme Oxygenase System in Microvessel Endothelial Cells / N.G. Abraham, R. Olszanecki 59

13. Cytochrome P450 Arachidonic Acid Metabolites Modulate Renal Tubular Function / M.A. Carroll, N.R. Ferreri, B.A. Escalante, A.O. Oyekan, J.C. McGiff 67

Receptors and Inhibitors

14. Thromboxane-induced ERK Phosphorylation in Human Aortic Smooth Muscle Cells / C. Gallet, S. Blaie, S. Levy-Toledano, A. Habib 71

15. Arachidonic Acid Inhibits Cysteinyl-Leukotriene Receptor Activation In Human Pulmonary Vessels / L. Walch, X. Norel, J.-P. Gascard, C. Brink 75

Phospholipases and Inhibitors

16. Cytosolic Phospholipase A[subscript 2 alpha] in Mouse Platelets / D.A. Wong, N. Uozumi, Y. Kita, T. Shimizu 81

17. Cellular Arachidonate-Releasing Functions of Various Phospholipase A[subscript 2]s / M. Murakami, I. Kudo 87

18. Biological Functions of Group X Secretory PLA[subscript 2] / K. Hanasaki, H. Arita 93

19. Protection of Cell Membrane from Exogenous PLA[subscript 2] and Related Inflammatory Stimuli by Membrane-Anchored Lipid Conjugates / S. Yedgar, M. Krimsky, O. Schwob 97

Prostaglandin Synthases and Receptor Signaling

20. Regulatory Functions of Prostaglandin E[subscript 2] Synthases / I. Kudo, M. Murakami 103

21. A Novel Type of Membrane-Associated Prostaglandin E Synthase / K. Watanabe, Y. Ohmiya, H. Ohkubo, N. Tanikawa, M. Kojima, S. Ito 107

22. Expression, Purification and Characterization of Recombinant Human Microsomal PGE[subscript 2] Synthase-1 / M. Ouellet, A. Pen, P.-H. Ear, J.-P. Falgueyret, T.G. LeRiche, J.A. Mancini, D. Riendeau, M.D. Percival 113

Cyclooxygenase and Lipoxygenase Pathways and Inhibitors

23. Formation of Prostaglandin E[subscript 2], Leukotriene B[subscript 4] and 8-Isoprostane in Alveolar Macrophages by Ultrafine Particles of Elemental Carbon / I. Beck-Speier, N. Dayal, E. Karg, K.L. Maier, H. Schulz, G. Schumann, A. Ziesenis, J. Heyder 117

24. Effects of PGF[subscript 2 alpha] Analogues in Experimental Morphine-Induced Pharmacodependence / M. Nechifor, D. Chelarescu, E. Teslariu, F. Cocu, A. Negru 121

25. Inhibition of Prostaglandin H[subscript 2] Synthases by Salicylate is Dependent on the Oxidative State of the Enzymes / D.M. Aronoff, O. Boutaud, L.J. Marnett, J.A. Oates 125

26. 5-Lipoxygenase Activation by MAPKAPK-2 and ERKs / O. Werz, E. Burkert, L. Fischer, D. Szellas, D. Dishart, B. Samuelsson, O. Radmark, D. Steinhilber 129

27. Renal Effects of Selective Cyclooxygenase Inhibition in Experimental Liver Disease / M. Lopez-Parra, J. Claria, A. Planaguma, E. Titos, J.L. Masferrer, B.M. Woerner, A.T. Koki, W. Jimenez, V. Arroyo, F. Rivera, J. Rodes 133

28. Variable Antipyretic Effect of SC-58236, a Selective Cyclooxygenase (COX)-2 Inhibitor, in Rats / E.S. Akarsu, S. Mamuk, S. Arat 137

Genetics and Genomics

29. Induction of Cyclooxygenase-2 Expression by Fluid Shear Stress in Vascular Endothelial Cells / H. Inoue, Y. Taba, Y. Miwa, C. Yokota, M. Miyagi, T. Sasaguri 141

30. Induction of COX-2 Expression by the Endocannabinoid Derivative R(+)-Methanandamide / B. Hinz, R. Ramer, K. Brune 145

31. Specific Gene Expression of Isoforms in Cyclooxygenase Pathway to Generate PGJ[subscript 2] Derivatives During the Differentiation of 3t3-L1 Adipocytes / S. Lu, M. Ohya, K. Nishimura, M. Jisaka, T. Nagaya, K. Yokota 153

32. Tristetrapolin Binds to the COX-2 MRNA 3' Untranslated Region in Cancer Cells / O. Boutaud, D.A. Dixon, J.A. Oates, H. Sawaoka 157

33. Platelet Activating Factor Receptors / A.M. Marrache, F. Gobeil Jr., S.G. Bernier, J. Stankova, M. Rola-Pleszczynski, S. Choufani, G. Bkaily, A. Bourdeau, M.G. Sirois, A. Vazquez-Tello, L. Fan, J.-S. Joyal, J.G. Filep, D.R. Varma, A. Ribeiro-da-Silva, S. Chemtob 161

34. Splicing Mutation of the Prostacyclin Synthase Gene in a Family Associated with Hypertension / T. Nakayama, M. Soma, Y. Watanabe, B. Hasimu, K. Kanmatsuse, S. Kokubun, J.D. Morrow, J.A. Oates 165

35. DNA Methylation Regulates 5-Lipoxygenase Promoter Activity / J. Uhl, N. Klan, M. Rose, K.-D. Entian, O. Werz, D. Steinhilber 169

Lipid Peroxidation, Apoptosis and Fatty Acids

36. Isomerization and Nitro-Oxidation of Arachidonic Acid by NO[subscript 2] / M. Balazy, J. Lopez-Fernandez 173

37. Prostaglandin F[subscript 2 alpha] Protected Cultured Madin-Darby Canine Kidney Cells from the Development of Apoptosis Induced by 12-O-Tetradecanoyl Phorbol-[beta]-Acetate and Stimulated Synergistically with Nordihydroguaiaretic Acid / K. Nishimura, H. Tsumagari, A. Morioka, S. Lu, M. Jisaka, T. Nagaya, K. Yokota 177

38. LDL Receptor-Related Protein Plays an Essential Role in 12/15-Lipoxygenase-Mediated LDL Oxidation by Macrophages / W. Xu, Y. Takahashi, T. Iwasaki, H. Hattori, T. Yoshimoto 181

39. Effects of in vitro Exposure to Carbon Dioxide on the Expression of Apoptosis-Associated Genes in Human Peritoneal Fibroblasts / A.M.B. Souza, C.M. Briton-Jones, C.C. Wang, C.J. Haines, M.S. Rogers 185

40. Identification, Characterization, and Properties of a Class Alpha Microsomal Glutathione S-Transferase / K.S. Prabhu, P.V. Reddy, A.D. Liken, E.C. Jones, H.P. Yennawar, C.C. Reddy 189

Cardiovascular System

41. Cyclooxygenase (COX) Function in The Ductus Arteriosus: Another Look / F. Coceani, B. Baragatti, F. Brizzi, S. Barogi, C. Ackerley 193

42. Evidence for Enhanced Oxidative Stress in Coronary Heart Disease and Chronic Heart Failure / R. Wolfram, A. Oguogho, B. Palumbo, H. Sinzinger 197

Angiogenesis and Cancer

43. The Leukotriene Receptor CYSLT[subscript 1] and 5-Lipoxygenase are Upregulated in Colon Cancer / C.K. Nielsen, J.F. Ohd, K. Wikstrom, R. Massoumi, S. Paruchuri, M. Juhas, A. Sjolander 201

44. Increased Expression of 5-Lipoxygenase in Glioblastoma Multiforme / M. Golubic, R.A. Prayson, L. Vargo, J. Bondar, G.H. Barnett 205

Isoprostanes

45. Variable Influence of Statins on Isoprostanes in Hyperlipidemia / H. Sinzinger, A. Oguogho 209

46. Increased Isoprostanes in Children of Smoking Parents / H. Sinzinger, A. Oguogho, H. Pilz 213

47. The Dinor Isoprostane Pathway in Plants / C. Loeffler, I. Thoma, M. Krischke, M.J. Mueller 217.

Notes:

"Proceedings of the 12th International Conference on Advances in Prostaglandin, Leukotriene, and Other Bioactive Lipid Research: Basic Science and Clinical Applications, held August 25-29, 2002, in Istanbul, Turkey."--T. p. verso.

Includes index.

Includes bibliographical references.

ISBN:

0306477637

OCLC:

52165954