Venous thrombosis in women : pregnancy, the contraceptive pill, and hormone replacement therapy / I. A. Greer.

Format:

Book

Author/Creator:

Greer, I. A. (Ian A.), 1958-

Language:

English

Subjects (All):

Blood coagulation disorders in pregnancy.

Thrombophlebitis.

Women--Diseases.

Women.

Pregnancy--Complications.

Pregnancy.

Blood--Coagulation.

Blood.

Oral contraceptives--Side effects.

Oral contraceptives.

Menopause--Hormone therapy--Complications.

Menopause.

Venous Thrombosis.

Pregnancy Complications.

Contraceptive Agents--adverse effects.

Hormone Replacement Therapy--adverse effects.

Medical Subjects:

Venous Thrombosis.

Pregnancy Complications.

Contraceptive Agents--adverse effects.

Hormone Replacement Therapy--adverse effects.

Physical Description:

112 pages : illustrations ; 26 cm

Place of Publication:

Boca Raton : Parthenon Pub., 2003.

Contents:

1. Overview of the hemostatic and fibrinolytic systems 7

2. Physiological changes in hemostasis and fibrinolysis in pregnancy 15

2.1 Platelets in pregnancy 16

2.2 Coagulation factors 16

2.3 Endogenous anticoagulants and pregnancy 17

2.4 Fibrinolysis 18

2.5 Summary: hemostasis in normal pregnancy 19

3. Venous thromboembolism in pregnancy 21

3.1 The problem of venous thromboembolism in pregnancy 22

3.2 Risk factors for VTE in pregnancy 23

3.3 Long-term morbidity from pregnancy-associated VTE 26

3.4 Pathophysiology of pregnancy-associated VTE 27

3.5 Thrombophilia and pregnancy-associated venous thrombosis 29

3.6 Thrombophilia and adverse pregnancy outcome 34

3.7 Screening for congenital thrombophilia in pregnancy 39

3.8 Diagnosis of VTE in pregnancy 41

3.9 Antithrombotic therapy in pregnancy 44

3.10 Management of acute gestational VTE 47

3.11 Labor and Cesarean section in the woman with VTE in pregnancy 51

3.12 Thromboprophylaxis in pregnancy 52

4. Venous thromboembolism and the oral contraceptive pill 59

4.1 Epidemiology of venous thromboembolism and the oral contraceptive pill 60

4.2 Heritable thrombophilia and the oral contraceptive pill 64

4.3 Hemostatic effects of the combined oral contraceptive pill 66

4.4 Implications for practice 66

5. Venous thromboembolism and hormone replacement therapy 69

5.1 Epidemiology of venous thromboembolism and hormone replacement therapy 70

5.2 Potential mechanisms underlying the association between HRT and VTE 76

5.3 Thrombophilia, HRT and risk of VTE 78

5.4 Risk factors for VTE and HRT 79

5.5 HRT and VTE: implications for management 81.

Notes:

Includes bibliographical references (pages 85-106) and index.

ISBN:

1842142283

OCLC:

52001233