Colonic diseases / edited by Timothy R. Koch ; foreword by Joseph B. Kirsner.

Format:

Book

Contributor:

Koch, Timothy R.

Language:

English

Subjects (All):

Colon (Anatomy)--Diseases.

Colon (Anatomy).

Colon (Anatomy)--Pathophysiology.

Colonic Diseases.

Rectal Diseases.

Colon--physiology.

Rectum--physiology.

Physiology, Pathological.

Medical Subjects:

Colonic Diseases.

Rectal Diseases.

Colon--physiology.

Rectum--physiology.

Physical Description:

xviii, 553 pages, 12 unnumbered pages of plates : illustrations (some color) ; 26 cm

Place of Publication:

Totowa, N.J. : Humana Press, [2003]

Summary:

With an aging population prone to colorectal disorders and with the quickening pace of medical discovery, there is a need for an up-to-date survey of the field. In Colonic Diseases, Timothy R. Koch, MD, has assembled a panel of innovative basic researchers, esteemed clinical investigators, and well-known clinicians to bridge the gap between basic and clinical research and the day-to-day care of patients with colonic disorders. As a foundation for better understanding, the authors review what is currently known about normal colonic physiology, explain the mechanisms of disease involved in the development of colonic disorders, and highlight important clues for potential therapies. Their review of the diagnosis and treatment of common colonic disorders covers colorectal neoplasia, inflammatory bowel disease (IBD), ulcerative colitis, diverticular disease, Crohn's disease, and constipation. Here the authors fully discuss potential symptoms, pathological and radiological findings, the differential diagnosis, and presently recommended modes of evaluation and therapy, including the use of probiotics. New areas of potential treatment not presently available for patients with chronic symptoms are also examined, along with the advanced treatment techniques currently in use at the Cleveland Clinic (for ulcerative colitis), The University of Chicago (for Crohn's disease), the Mayo Clinic (for irritable bowel syndrome), and the MD Anderson Cancer Center (for colorectal cancer). Timely and cutting-edge, Colonic Diseases explains the origins and treatment of common colorectal disorders, blending the molecular mechanisms of disease with new outcomes and epidemiological research to improve our present and future understanding of colonic diseases and their management.

Contents:

Part I. Colorectal Physiology

1 Absorption-Secretion and Epithelial Cell Function / Pradeep K. Dudeja, Ravinder Gill, K. Ramaswamy 3

2 Normal Motility and Smooth Muscle Function / Mary Francis Otterson 25

3 Neural Regulation of Colonic Motor Function / Kenton M. Sanders, Terence K. Smith 35

4 Mucin and Goblet Cell Function / Samuel B. Ho, Laurie L. Shekels 53

5 Endocrine Cells of the Colon / Sebastian G. de la Fuente, Christopher R. Mantyh, Theodore N. Pappas 73

6 Micronutrients / Emmanuel C. Opara 85

7 Aging / Emmanuel C. Opara, Timothy R. Koch 95

8 Immunology of the Gastrointestinal Tract / Jonathan R. Fulton, Cynthia A. Cunningham, Christopher F. Cuff 105

9 Colonic Lymphatics / Stacey A. Weiland, Yang K. Chen 123

10 Probiotics and the Colon: Therapeutic and Prophylactic Uses / Thomas J. Borody, Patricia L. Conway 141

11 Physiology and Pathophysiology of Colorectal Sensory Processes / Michael D. Crowell, Brian E. Lacy 163

Part II. Investigation of Disease Processes

12 Oxidative Stress / Emmanuel C. Opara 179

13 Genetic Testing for Colon Cancer / Russell F. Jacoby, Carolyn E. Cole 191

14 Inflammation / Cynthia A. Cunningham, Jonathan R. Fulton, Christopher F. Cuff 211

15 Epidemiologic Studies and Outcomes Research in Colonic Diseases / John F. Johanson 227

16 Colonoscopy / Donald G. Seibert 243

17 Interpretation of Colonic Biopsies in Patients with Diarrhea / Sarah M. Dry, Galen R. Cortina, Klaus J. Lewin 275

18 Anorectal Manometry / Devang N. Prajapati, Walter J. Hogan 297

19 Endoanal and Endorectal Ultrasound / Lisa M. Gangarosa 321

20 Colonic Transit and Motility / William J. Snape, Jr. 335

21 Defecography and Related Radiologic Techniques / Vincent H. S. Low 345

22 Cross-Sectional Imaging of the Large Bowel / Diego R. Martin, Ming Yang, Paul Hamilton 357

Part III. Colorectal Disease

23 Hirschsprung's Disease and Neonatal Disorders / Carol Lynn Berseth 383

24 Acute Megacolon, Acquired Megacolon, and Volvulus / Marc Stauffer, Timothy R. Koch 395

25 Diverticular Disease / Gordon L. Telford, Susan W. Telford, Mary F. Otterson 409

26 Current Understanding of Colorectal Neoplasia / Melanie B. Thomas, Robert A. Wolff 423

27 Constipation / Anne Lutz-Vorderbruegge, Arnd Schulte-Bockholt 441

28 Crohn's Disease / Amit G. Shah, Stephen B. Hanauer 459

29 Ulcerative Colitis / Bret A. Lashner 479

30 Irritable Bowel Syndrome / Michael Camilleri 491

31 Ischemic Colitis / Peter Grubel, David R. Cave 505

32 Surgical Treatments for Colonic Diseases / Joseph P. Muldoon, Steven J. Stryker 523

33 Anorectal Disorders / Mohammed M. H. Kalan, Bruce A. Orkin 535.

Notes:

Includes bibliographical references and index.

ISBN:

0896039617

1592593143

OCLC:

50511223