Biostatistical applications in cancer research / edited by Craig Beam.

Format:

Book

Contributor:

Beam, Craig, 1953-

Series:

Cancer treatment and research ; v. 113.

Cancer treatment and research ; v. 113

Language:

English

Subjects (All):

Cancer--Research--Statistical methods.

Cancer.

Neoplasms--epidemiology.

Biometry--methods.

Statistics as Topic--methods.

Cancer--Research.

Medical Subjects:

Neoplasms--epidemiology.

Biometry--methods.

Statistics as Topic--methods.

Physical Description:

viii, 238 pages : illustrations ; 25 cm.

Place of Publication:

Boston : Kluwer Academic Publishers, [2002]

Summary:

Biostatistics is defined as much by its application as it is by theory. This book provides an introduction to biostatistical applications in modern cancer research that is both accessible and valuable to the cancer biostatistician or to the cancer researcher, learning biostatistics. The topical areas include active areas of the application of biostatistics to modern cancer research: survival analysis, screening, diagnostics, spatial analysis and the analysis of microarray data. Biostatistics is an essential component of basic and clinical cancer research. The text, authored by distinguished figures in the field, addresses clinical issues in statistical analysis. The spectrum of topics discussed ranges from fundamental methodology to clinical and translational applications.

Contents:

1. Models and the Early Detection of Disease: Methodological Considerations / M. Zelen, S. J. Lee 1

2. Statistical Models for Screening: Planning Public Health Programs / S. J. Lee, M. Zelen 19

3. Survival Analysis Methods in Cancer Studies / J. P. Klein 37

4. Cox Proportional Hazards Regression Models for Survival Data in Cancer Research / M. Zhang 59

5. Some Aspects of Analysis of Gene Array Data / B. D. Jovanovic, R. C. Bergan, W. A. Kibbe 71

6. An Analysis of Gene Array Data Related to Cell Adhesion and Prostate Cancer / B. D. Jovanovic, S. Huang, Y. Liu, K. N. Naguib, R. C. Bergan 91

7. Spatial Analysis of Disease / L. W. Pickle 113

8. Spatial Analysis of Disease - Applications / B. S. Bell 151

9. Cancer Diagnostics: Statistical Methods / A. Y. Toledano 183

10. Case Study: Evaluating Accuracy of Cancer Diagnostic Tests / A. Y. Toledano, B. A. Herman 219.

Notes:

Includes bibliographical references and index.

ISBN:

1402072260

OCLC:

50554792