1 option
Jaagsiekte sheep retrovirus and lung cancer / H.Y. Fan (ed.).
Holman Biotech Commons QR1 .E6 v.275 2003
Available
- Format:
- Book
- Series:
- Current topics in microbiology and immunology ; v. 275.
- Current topics in microbiology and immunology ; v. 275
- Language:
- English
- Subjects (All):
- Retroviruses.
- Sheep--Virus diseases.
- Sheep.
- Oncogenic viruses.
- Lungs--Cancer--Etiology.
- Lungs.
- Retroviridae.
- Jaagsiekte sheep retrovirus.
- Oncogenic Viruses.
- Lung Neoplasms--veterinary.
- Lung Neoplasms--etiology.
- Virus Diseases--veterinary.
- Sheep Diseases.
- Medical Subjects:
- Retroviridae.
- Jaagsiekte sheep retrovirus.
- Oncogenic Viruses.
- Lung Neoplasms--veterinary.
- Lung Neoplasms--etiology.
- Virus Diseases--veterinary.
- Sheep Diseases.
- Physical Description:
- vii, 252 pages : illustrations ; 25 cm.
- Place of Publication:
- Berlin ; New York : Springer, 2003.
- Summary:
- Retroviruses have been of great importance to biomedical science for the past half century. Initially, studies on oncogenic animal retroviruses provided important insights into molecular processes in carcinogenesis most notably the existence and mechanisms of action of oncogenes and proto-oncogenes. Moreover, several human diseases are caused by retroviruses, including AIDS, adult T-cell leukemia and the neurological disease HAM/TSP. The topic of this volume is a relatively unknown animal retrovirus, jaagsiekte sheep retrovirus, the causative agent of transmissible lung cancer in sheep ovine pulmonary adenocarcinoma. The disease was first documented in South Africa in the 1800s, it has a wide geographical distribution, and it is of economic importance in high endemic regions. However, until very recently the nature of the etiologic agent was unclear, and relatively few laboratories actively studied the disease.
- Contents:
- A History of Ovine Pulmonary Adenocarcinoma (Jaagsiekte) and Experiments Leading to the Deduction of the JSRV Nucleotide Sequence / D.F. York, G. Querat 1
- Pathology of Ovine Pulmonary Adenocarcinoma / M. De las Heras, L. Gonzalez, J.M. Sharp 25
- Natural History of JSRV in Sheep / J.M. Sharp, J.C. DeMartini 55
- Molecular Biology of Jaagsiekte Sheep Retrovirus / M. Palmarini, H. Fan 81
- Endogenous Retroviruses Related to Jaagsiekte Sheep Retrovirus / J.C. DeMartini, J.O. Carlson, C. Leroux, T. Spencer, M. Palmarini 117
- Transformation and Oncogenesis by Jaagsiekte Sheep Retrovirus / H. Fan, M. Palmarini, J.C. DeMartini 139
- Identification of Hyal2 as the Cell-Surface Receptor for Jaagsiekte Sheep Retrovirus and Ovine Nasal Adenocarcinoma Virus / A.D. Miller 179
- Enzootic Nasal Adenocarcinoma of Sheep and Goats / M. De las Heras, A. Ortin, C. Cousens, E. Minguijon, J.M. Sharp 201
- Pathology of Human Bronchioloalveolar Carcinoma and Its Relationship to the Ovine Disease / J.-F. Mornex, F. Thivolet, M. De las Heras, C. Leroux 225.
- Notes:
- Includes bibliographical references and index.
- ISBN:
- 3540440968
- OCLC:
- 215553677
The Penn Libraries is committed to describing library materials using current, accurate, and responsible language. If you discover outdated or inaccurate language, please fill out this feedback form to report it and suggest alternative language.