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Oxford handbook of applied dental sciences / edited by Crispian Scully.

Levy Dental Medicine Library - Stacks RK56 .O95 2002
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Format:
Book
Contributor:
Scully, Crispian.
Language:
English
Subjects (All):
Dentistry--Handbooks, manuals, etc.
Dentistry.
Dentistry--Examinations, questions, etc.
Genre:
Handbooks and manuals.
Examinations.
Physical Description:
xx, 642 pages : illustrations ; 19 cm
Other Title:
Handbook of applied dental sciences
Place of Publication:
Oxford ; New York : Oxford University Press, 2002.
Summary:
The Oxford Handbook of Applied Dental Preclinical Sciences covers the medical sciences for the preclinical dental student in a concise and easily accessible format. An international team of experts in dental education and research provide information on the applied basic sciences sciences to ensure a sound understanding of why the medical sciences are relevant to clinical dental practice. Anatomy and development, pain and behavioural sciences, biochemistry, genomics, immunology, microbiology, pathology, and physiology are all covered. Emphasis is placed on advances in the sciences, the changed content of subjects, and the relevance to dental clinical practice are well illustrated. Critical evaluation and communication skills have also been addressed to ensure that this Handbook will provide all the information necessary for a comprehensive understanding of the subject.
Contents:
Part 1 Development and anatomy
1 Craniofacial development 3
Mechanisms of craniofacial growth control 10
2 General anatomy 11
Skin 15
The skeletal system 16
The nervous system 18
The cardiovascular system 22
Bone 26
3 Anatomy of the head and neck 35
The scalp 36
The face 37
The temporal region 40
The ear 42
The eye 45
The nasal cavity 48
4 Oral anatomy: the oral cavity, salivary glands, and the temporomandibular joint 51
The palate 54
Floor of the mouth 56
The tongue 57
The salivary glands 60
The temporomandibular joint (TMJ) 63
5 The neck 67
Deep fascia 68
The triangles of the neck 73
The cervical nerve plexus 75
Midline structures of the neck 76
The thyroid gland 80
The pharynx 81
6 Teeth 85
Tooth structure 87
Enamel 88
Dentin-pulp complex 93
Pulp 98
Dentin sensitivity 99
Cementum 100
Periodontal ligament (PDL) 101
Alveolar process 107
7 Odontogenesis 109
Stages in tooth development 110
Root formation 115
Pulp formation 116
8 Tooth eruption 117
Mechanisms of tooth eruption 121
Part 2 Physiology
9 Cell physiology 125
The membrane potential 128
Active transport 129
Exocytosis 130
Intracellular signalling 131
10 Neurophysiology 133
Basic mechanisms 135
Action potential 136
The synapse 139
Sensory transduction 142
Sensory receptors in oral structures 144
11 Mastication 149
Muscles of mastication 151
Chewing cycles 152
Control of mastication 153
Forces generated by masticatory muscles 156
12 Salivary gland function 157
Saliva 159
Function of saliva 161
Xerostomia 163
13 Swallowing 165
Neural control of swallowing 169
Suckling 170
14 Digestion and absorption 171
Stomach 175
Intestines 178
The exocrine pancreas 181
Bile 183
15 Liver 185
16 Kidneys 189
Ultrafiltration 191
Renal tubular excretion and reabsorption 192
Renal (kidney) functions 193
17 Vitamins 195
18 Blood 199
Hematopoiesis 201
Red blood cells (RBCs) 202
White blood cells (leukocytes) 204
Platelets 204
Hemostasis 206
Complement 208
19 Cardiovascular system 209
Cardiac function 211
Cardiac output 212
Cardiac malfunction 213
Blood pressure 214
20 Respiratory system 219
Lung function 220
Oxygen and carbon dioxide transport 221
Neural control of respiration 222
21 Endocrine system 223
Growth hormone (GH) (somatotrophin) 225
Adrenocorticotropic hormone (ACTH) (corticotrophin) 226
Luteinizing (LH) and follicle stimulating hormone (FSH) 227
Thyroid stimulating hormone (TSH) 228
Melanocyte stimulating hormone 229
Antidiuretic hormone (ADH) (vasopressin) 230
Oxytocin 231
Melatonin 232
Thyroid hormone (thyroxine, tri-iodothyronine) 233
Parathyroid hormone 234
Vitamin D 235
Calcitonin 236
Epinephrine (adrenaline) and norepinephrine (noradrenaline) 237
Glucocorticoids 238
Mineralocorticoids 239
Insulin 240
Glucagon 241
Somatostatin 242
Estrogen 243
Progesterone 244
Testosterone 245
Gastrin 246
Secretin 247
Cholecystokinin 248
22 Bone 249
Bone cells 252
Bone formation (osteogenesis) 255
Bone modeling and remodeling 256
Bone fracture repair 256
Bone mineral homeostasis 258
Hormonal control of calcium and bone metabolism 260
Orthodontic tooth movement 262
23 Wound healing 265
Part 3 Biochemistry
24 Molecular architecture 271
Proteins 272
Nucleic acids 274
Carbohydrates 277
Lipids 279
Enzymes 280
25 Protein expression, analysis, and proteomics 283
Amino acid biosynthesis 285
Direction of protein synthesis 286
Genetic code 287
Protein synthesis 289
Protein function 291
Proteins in health and disease 294
Examining protein expression in cells and tissues 295
Expression of exogenous proteins in cultured cells 297
Protein-protein interactions 300
Analysis of protein function in vivo
transgenic approaches 301
Clinical aspects of protein analysis 302
Computer-based analysis of expression patterns
bioinformatics 303
Proteomics 305
26 Metabolism 307
Metabolism of carbohydrates 309
Metabolism of lipids 311
Metabolism of nucleic acids 313
Metabolism of proteins and amino acids 314
27 Cell signaling 317
Features of cell signaling 319
Types of cell signaling 320
Types of signal 321
Cell signaling pathways 322
28 Cells and tissues 325
Epithelial tissues 326
Connective tissue 328
Basement membrane 333
29 Mineralized tissues 335
Metabolism of calcium and phosphorus 337
Biological apatite 338
The mineralization process 339
30 Teeth 341
Enamel 342
Dentin 345
Dental pulp 348
31 The periodontal tissues 349
Gingiva 350
Oral mucosa 352
Crevicular fluid 353
Periodontal ligament 354
Cementum 355
32 The temporomandibular joint 357
Articular surfaces 359
Interarticular meniscus (TMJ disc) 360
Synovial fluid 361
33 Saliva and the biochemical aspects of oral homeostasis 363
Physicochemical properties of saliva 365
Composition of saliva 366
Functions of saliva 368
34 Dental plaque 369
Formation and properties of dental plaque 370
Properties of mature plaque 372
Plaque metabolism and dental disease 373
Plaque metabolism and periodontal disease 375
Part 4 Genomics
Structural genomics 381
Comparative genomics 383
Functional genomics 384
Bioinformatics 385
Applications of genomics 386
Bioethical questions arising from genomics 388
36 Human genetics 389
Clinical relevance: case study 391
Modes of inheritance 393
Case study continued: finding the cause of the problem 397
The genetic code 404
Genetic counselling 405
Gene therapy and prenatal testing 406
37 Craniofacial development 407
Sequence of development 408
Regulation of development 409
Genetic basis of development 410
Transcription factors and signaling molecules 411
38 Palate development 413
Primary palate development 414
Secondary palate development 415
Regulation of palate development 417
Genetic basis of abnormal palate development 420
39 Tooth development 423
Outline of tooth development 424
Regulation of tooth development 426
Genetic basis of abnormal tooth development 428
Part 5 General immunology
Circulatory system and lymphatic system 435
Cells and tissues of the immune system 436
Innate immunity 439
Generation of diversity 444
41 Humoral and soluble mediators of the immune response 449
Immunoglobulins 450
Antibody responses 453
Antigen-antibody interactions 455
Soluble mediators of the immune response 457
Immunological memory 459
42 Cell-mediated immunity 461
Natural killer (NK) cells 463
Immunological memory 464
Immunological responses to infectious disease 465
43 Clinical immunology 469
Immunization 470
Hypersensitivity responses 472
Autoimmunity 474
Cancer 475
Immunodeficiency 476
Transplantation immunology 480
Part 6 Pathology
44 Cell and tissue damage 483
Inflammation 484
Responses which may or may not be preceded by inflammation 490
45 Hemodynamic disorders 493
Edema 494
Thromboembolism 495
Infarction 496
Shock 497
46 Neoplasia 499
Cancer 501
Oncogenesis 503
Epidemiology of cancer 509
47 Genetic and developmental disorders 513
Genetic and developmental abnormalities 516
48 Nutritional diseases 519
Protein-energy malnutrition 520
Vitamin deficiency 522
Obesity 523
Part 7 Microbiology
49 Bacteria 527
Morphology and structure 529
Nutrition, growth, and cultivation 532
Classification of bacteria 534
Bacterial genetics 535
50 Bacteria and disease 537
Normal (commensal) microflora 538
Diseases
caused by the normal bacterial microflora 540
Diseases caused by exogenous bacterial pathogens 541
Bacterial virulence factors 542
Antimicrobial chemotherapy 543
Diagnostic bacteriology 545
51 Major bacteria and the diseases they can cause 547
Gram-positive cocci 548
Gram-negative cocci 551
Gram-positive, spore-forming bacilli 553
Gram-positive, non-spore-forming bacilli 555
Gram-negative, aerobic bacilli 556
Gram-negative, facultative bacilli 559
Gram-negative, curved bacilli 561
Miscellaneous organisms 563
52 Viruses and viral infections 565
Principles of virology 566
Routes of viral infection 567
Viral replication 568
Effects of viruses on host cells 569
Laboratory diagnosis of viral infection 570
53 Main viral infections 571
Viral hepatitis 572
Retroviruses 576
Herpesviruses 579
Other relevant viruses 582
Prions 583
54 Fungi and fungal infections 585
Fungal biology 586
Human mycoses 587
Part 8 Behavioral sciences and pain
55 The dentist-patient relationship 593
Types of relationship 595
Communication skills 596
Principles of behavior change 598
Adherence to treatment 600
56 Personality, mood, and psychiatric disorders 603
Personality 604
Mood 605
Psychoses 608
57 Pain 609
Perception of pain 613
Control of pain 614
58 Orofacial pain 615
Chronic idiopathic facial pain 617.
Notes:
Includes index.
ISBN:
0198510969
OCLC:
49844232

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