Biomedical imaging in experimental neuroscience / edited by Nick Van Bruggen and Timothy Roberts.

Format:

Book

Contributor:

Van Bruggen, Nick.

Roberts, Timothy (Timothy P. L.)

Series:

Methods & new frontiers in neuroscience series

Methods & new frontiers in neuroscience

Language:

English

Subjects (All):

Brain--Imaging.

Brain.

Brain--Magnetic resonance imaging.

Magnetic Resonance Imaging.

Medical Subjects:

Brain.

Magnetic Resonance Imaging.

Physical Description:

351 pages, 24 unnumbered pages of plates : illustrations (some color) ; 25 cm.

Place of Publication:

Boca Raton, Fla. : CRC Press, [2003]

Summary:

With the emergence of genetically manipulated laboratory mice and the knowledge of the mouse genome, we are entering an exciting new era with revolutionary tools for experimental research in neuroscience. Noninvasive imaging techniques capable of providing both anatomical and functional descriptions of the brain have become essential. Among the various imaging methodologies, magnetic resonance imaging (MRI) stands in the forefront by virtue of its contrast versatility and pathophysiological specificity. Emphasizing the relationship between physiological microenvironment and macroscopic imaging signal changes, Biomedical Imaging in Experimental Neuroscience presents a comprehensive review of the noninvasive biomedical imaging techniques available for laboratory animal research. Focusing on MRI, but recognizing the multiple forms of imaging information, this book outlines the scope and limitations of these methods and analyzes their impact on in vivo neuroscience research. Biomedical Imaging in Experimental Neuroscience presents detailed information for biologists interested in knowing how biomedical imaging may augment their in vivo research and for clinical practitioners seeking deeper insights into the association between imaging findings and disease pathophysiology.

Contents:

Chapter 1 Principles of MRI Contrast / Timothy P.L. Roberts, Nick van Bruggen 1

Chapter 2 MRI Measurement of Cerebral Perfusion and Application to Experimental Neuroscience / Mark F. Lythgoe, David L. Thomas, Fernando Calamante 21

Chapter 3 MRI Measurement of Cerebral Water Diffusion and Its Application to Experimental Research / Richard A.D. Carano, Nick van Bruggen, Alex J. de Crespigny 55

Chapter 4 Functional Magnetic Resonance Imaging / Mathias Hoehn 93

Chapter 5 Functional Imaging in Nonhuman Primates / Elizabeth Disbrow 137

Chapter 6 Pharmacologic Magnetic Resonance Imaging (phMRI) / Bruce G. Jenkins, Yin-Ching I. Chen, Joseph B. Mandeville 155

Chapter 7 Anatomical Studies in the Rodent Brain and Spinal Cord: Applications of Magnetic Resonance Microscopy / Helene Benveniste, Tom Mareci, Steve Blackband 211

Chapter 8 Magnetic Resonance Spectroscopy: Principles and Applications / Stephen R. Williams, Nicola R. Sibson 237

Chapter 9 Small Animal Imaging with Positron Emission Tomography / Simon R. Cherry, Harley I. Kornblum 271

Chapter 10 MRI and Novel Contrast Agents for Molecular Imaging / Michel M. Modo, Steven C.R. Williams 293

Chapter 11 The Future for Biomedical Imaging: Emerging and Alternative Technologies / Nick van Bruggen, Timothy P.L. Roberts 323.

Notes:

Includes bibliographical references and index.

ISBN:

084930122X

OCLC:

50285367