Clinical chemistry : theory, analysis, correlation / [edited by] Lawrence A. Kaplan, Amadeo J. Pesce, Steven C. Kazmierczak.

Format:

Book

Contributor:

Kaplan, Lawrence A., 1944-

Pesce, Amadeo J.

Kazmierczak, Steven C.

Language:

English

Subjects (All):

Clinical chemistry.

Chemistry, Clinical.

Medical Subjects:

Chemistry, Clinical.

Physical Description:

xvi, 1179 pages : illustrations ; 29 cm + 1 CD-ROM (color ; 4 3/4 in.)

4 3/4 in.

polychrome

Edition:

Fourth edition.

Place of Publication:

St. Louis : Mosby, [2003]

System Details:

text file

Summary:

This comprehensive, up-to-date, readable text acts as a complete clinical chemistry course and professional reference, providing detailed, specific information on the principles of clinical chemistry in laboratory diagnosis as well as the pathophysiologic changes that occur in disease and affect testing outcomes. Explanations of "Laboratory Techniques" (Part 1) lead the reader through various necessary laboratory techniques and practices. Chapters on "Pathophysiology" (Part 2) provide descriptions of how specific diseases affect the human body. A companion CD-ROM packaged with the book features Methods of Analysis, a comprehensive Urinalysis Manual, and an interactive Study Guide/Workbook to reinforce concepts. The book's clear writing and comprehensive coverage make it an ideal resource for both students and practitioners. Instructor resources are available to qualified adopters; contact your sales representative for more information.

Contents:

Part I Laboratory Techniques 1

1 Basic Laboratory Principles and Techniques / Bette Seamonds, Elizabeth Ann Byrne 3

Part 1 Basic Laboratory Principles and Techniques 5

Part 2 Calculations in Clinical Chemistry 34

2 Laboratory Management / Lawrence J. Crolla, Lisa Reninger, Paul W. Stiffler 45

3 Sources and Control of Preanalytical Variation / D. Robert Dufour 64

4 Spectral Techniques / Amadeo J. Pesce, Christopher S. Frings, Jack Gauldie 83

5 Chromatography: Theory and Practice / M. Wilson Tabor 107

6 Liquid Chromatography / David J. Anderson 129

7 Gas Chromatography / Alphonse Poklis 154

8 Mass Spectrometry / Michael Lehrer 171

9 Radioisotopes in Clinical Chemistry / I-Wen Chen 187

10 Electrophoresis / John M. Brewer 201

11 Immunological Reactions / Carolyn S. Feldkamp 216

12 Immunochemical Techniques / Carolyn S. Feldkamp 227

13 Principles for Competitive-Binding Assays / Stephan G. Thompson 246

14 Measurement of Colligative Properties / Lawrence A. Kaplan 265

15 Electrochemistry: Principles and Measurements / William R. Heineman, Jon R. Kirchhoff, John F. Wheeler, Craig E. Lunte, Sarah H. Jenkins 272

16 Laboratory Automation / Michael A. Pesce 287

17 Point-of-Care (Near-Patient) Testing / Ellis Jacobs 303

18 Laboratory Information Systems / David Chou 320

19 Laboratory Statistics / Stephen E. Kahn, Mark A. Jandreski 340

20 Reference Intervals and Clinical Decision Limits / Edward A. Sasse 362

21 Quality Control for the Clinical Chemistry Laboratory / Kenneth E. Blick, Richard B. Passey 379

22 Evaluation of Methods / Carl C. Garber, R. Neill Carey 402

23 Interferences in Chemical Analysis / Amadeo J. Pesce, Lawrence A. Kaplan 427

Part II Pathophysiology 439

24 Physiology and Pathophysiology of Body Water and Electrolytes / John M. Lorenz, Leonard I. Kleinman 441

25 Acid-Base Control and Acid-Base Disorders / John E. Sherwin 462

26 Renal Function / Martin Roy First 477

27 Liver Function / John E. Sherwin 492

28 Bone Disease / Oussama Itani, Reginald C. Tsang 507

29 The Pancreas: Function and Chemical Pathology / D. Robert Dufour 535

30 Gastrointestinal Function and Digestive Disease / D. Robert Dufour 549

31 Cardiac and Muscle Disease / Wendy R. Sanhai, Robert H. Christenson 566

32 Diabetes Mellitus / Richard F. Dods 580

33 Coronary Artery Disease and Disorders of Lipid Metabolism / Herbert K. Naito 603

Part 1 Lipids 604

Part 2 Lipoproteins 612

34 Alcoholism / Jeri D. Ropero-Miller, Ruth E. Winecker 639

35 Iron, Porphyrin, and Bilirubin Metabolism / William E. Schreiber 657

Part 1 Iron Metabolism 658

Part 2 Heme Synthesis and the Porphyrias 663

Part 3 Bilirubin 671

36 Hemoglobin / Harold R. Schumacher, Carmelita Alvares, Fermina M. Mazzella 675

37 Human Nutrition / Nancy W. Alcock 695

38 Trace Elements / Nancy W. Alcock 707

39 Vitamins / James G. Donnelly 722

40 Pregnancy and Fetal Development / John F. Chapman, Jr., Catherine A. Hammett-Stabler, Jane E. Phillips 753

41 Extravascular Biological Fluids / Lewis Glasser 779

42 Nervous System / Michael D. Privitera, Cathy Cao, Marcia Kaplan 787

43 General Endocrinology / Laurence M. Demers 809

44 Thyroid / Mariano Fernandez-Ulloa 827

45 The Gonads / Elisabeth Nye 849

46 Adrenal Hormones and Hypertension / Morris R. Pudek 876

Part 1 The Adrenal Hormones 878

Part 2 Hypertension 900

47 Diseases of Genetic Origin / Donald L. Rucknagel, Richard Wenstrup 907

48 Molecular Diagnostics / W. Edward Highsmith, Jr., Niel T. Constantine, Kenneth J. Friedman 937

49 Neoplasia / Barry N. Elkins 960

50 Laboratory Evaluation of the Transplant Recipient and Donor / Rita R. Alloway 972

51 Toxicology / Catherine A. Hammett-Stabler, Ruth E. Winecker, Jeri D. Ropero-Miller 989

52 Addiction and Substance Abuse / R. Jeffrey Goldsmith, Cheryl Lesar 1016

53 Classifications and Descriptions of Proteins, Lipids, and Carbohydrates / Lawrence A. Kaplan, Herbert K. Naito, Amadeo J. Pesce 1024

Part 1 Proteins 1025

Part 2 Lipids 1030

Part 3 Carbohydrates 1035

Part 4 Nucleic Acids 1037

54 Clinical Enzymology / David C. Hohnadel 1043

55 Isoenzymes and Isoforms / Wendy R. Sanhai, Robert H. Christenson 1064

56 Therapeutic Drug Monitoring (TDM) / Wolfgang A. Ritschel, Michael Oellerich, Victor W. Armstrong 1073

Part 1 Basic Overview of Principles 1075

Part 2 Practical Aspects of TDM 1086

57 Examination of Urine / Lawrence A. Kaplan, Amadeo J. Pesce 1092

Appendix A Buffer Solutions 1112

Appendix B Preparation of Buffer Solutions 1114

Appendix C Concentrations of Common Acids and Bases 1117

Appendix D Gases in Common Laboratory Use

Technical Information 1118

Appendix E Major Plasma Proteins 1120

Appendix F Conversions Between Conventional and SI Units 1122

Appendix G Conversions Between Conventional and SI Units for Specific Analytes 1123

Appendix H Body Surface of Children 1125

Appendix I Body Surface of Adults 1126.

Notes:

Includes bibliographical references and index.

ISBN:

0323017169

OCLC:

50198354