Cardiovascular pharmacotherapeutics / edited by William H. Frishman, Edmund H. Sonnenblick, Domenic A. Sica.

Format:

Book

Contributor:

Sonnenblick, Edmund H., 1932-2007.

Frishman, William H., 1946-

Sica, Domenic A.

Language:

English

Subjects (All):

Cardiovascular agents.

Cardiovascular Agents.

Cardiovascular Diseases--drug therapy.

Cardiovascular System--drug effects.

Medical Subjects:

Cardiovascular Agents.

Cardiovascular Diseases--drug therapy.

Cardiovascular System--drug effects.

Physical Description:

xxiv, 1072 pages : illustrations ; 29 cm

Edition:

Second edition.

Place of Publication:

New York : McGraw-Hill, Medical Pub. Division, [2003]

Summary:

Appendices provide you with practical, hands-on information on drug utilization in clinical practice

Contents:

1 Basic Principles of Clinical Pharmacology Relevant to Cardiology / Walter G. Levine, William H. Frishman 3

2 The Placebo Effect in Cardiovascular Disease / William H. Frishman, Wei-Nchih Lee, Stephen P. Glasser, Laura Bienenfeld, Peter Chien, Stephen J. Peterson 15

3 Compliance with Cardiovascular Drug Treatment / Piyush K. Dhanuka, Mary Welna Brown, Wei-Nchih Lee, Stephen J. Peterson, William H. Frishman 27

4 New Drug Development and FDA Approval / Eliot J. Lazar, Steven R. Bergmann 35

5 Health Economic Considerations in Cardiovascular Drug Utilization / Renee J. Goldberg Arnold, Diana J. Kaniecki 43

6 Cardiovascular Pharmacology: A Historical Perspective / W. Bruce Fye 57

Part II Drug Classes 65

7 Alpha- and Beta-Adrenergic Blocking Drugs / William H. Frishman 67

8 Cholinergic and Anticholinergic Drugs / B. Robert Meyer, William H. Frishman 99

9 Calcium Channel Blockers / William H. Frishman, Domenic A. Sica 105

10 The Renin-Angiotensin Axis: Angiotensin-Converting Enzyme Inhibitors and Angiotensin-Receptor Blockers / Domenic A. Sica, Todd W.B. Gehr, William H. Frishman 131

11 Diuretic Therapy in Cardiovascular Disease / Todd W.B. Gehr, Domenic A. Sica, William H. Frishman 157

12 Magnesium, Potassium, and Calcium as Potential Cardiovascular Disease Therapies / Domenic A. Sica, William H. Frishman, Erdal Cavusoglu 177

13 Inotropic Agents / Edmund H. Sonnenblick, Thierry H. LeJemtel, William H. Frishman 191

14 The Organic Nitrates and Nitroprusside / Jonathan Abrams, William H. Frishman 203

15 Antiadrenergic Drugs with Central Action and Neuron Depletors / Lawrence R. Krakoff 215

16 Nonspecific Antihypertensive Vasodilators / Lawrence R. Krakoff 221

17 Antiarrhythmic Drugs / Tatjana N. Sljapic, Peter R. Kowey, Eric L. Michelson 225

18 Antiplatelet and Antithrombotic Drugs / William H. Frishman, Robert G. Lerner, Michael D. Klein, Mira Roganovic 259

19 Thrombolytic Agents / Robert Forman, William H. Frishman 301

20 Lipid-Lowering Drugs / Neil S. Shachter, Peter Zimetbaum, William H. Frishman 317

21 Combination Drug Therapy / Michael A. Weber, Joel M. Neutel, William H. Frishman 355

22 Tobacco Smoking, Nicotine, and Nicotine and Non-Nicotine Smoking Cessation Therapies / William H. Frishman, Tom Ky, Anjum Ismail 369

23 Fish Oils, the B Vitamins, and Folic Acid as Cardiovascular Protective Agents / Nathan A. Kruger, William H. Frishman, Jamal Hussain 381

24 Antioxidant Vitamins and Enzymatic and Synthetic Oxygen-Derived Free-Radical Scavengers in the Prevention and Treatment of Cardiovascular Disease / William H. Frishman, Nathan A. Kruger, Devraj U. Nayak, Babak A. Vakili 407

25 Use of Prostacyclin and Its Analogues in the Treatment of Pulmonary Hypertension and Other Cardiovascular Diseases / William H. Frishman, Masoud Azizad, Yogesh Agarwal, Daniel W. Kang 429

26 Selective and Nonselective Dopamine-Receptor Agonists / William H. Frishman, Hilary Hotchkiss 443

27 Natriuretic and Other Vasoactive Peptides / William H. Frishman, Domenic A. Sica, Judy W.M. Cheng, Youngsoo Cho, Bradley G. Somer 451

Part III New Drug Classes in Development 479

28 Potassium-Channel Openers and Sodium/Hydrogen-Channel Effectors / William H. Frishman, Benjamin Y. Lee, Isaac Galandauer, Alex Huanphong Phan 481

29 Serotonin and Its Antagonists in Cardiovascular Disease / William J. Elliott, William H. Frishman 501

30 Imidazoline-Receptor Agonist Drugs for the Treatment of Systemic Hypertension and Congestive Heart Failure / William H. Frishman, Sameet A. Palkhiwala, Austin Yu, Fay Rim 515

31 Endothelin as a Therapeutic Target in the Treatment of Cardiovascular Disease / William H. Frishman, Sukhdeep Kaur, Inderpal Singh, Praveen Tamirisa 527

32 Adenosine-Receptor Agonism and Antagonism in Cardiovascular Disease / William H. Frishman, Eugenia Gianos, Jay Lee, Bradley G. Somer 545

33 Nitric Oxide Donor Drugs in the Treatment of Cardiovascular Diseases / William H. Frishman, Armin Helisch, Nauman Naseer, Jason Lyons, Richard M. Hays 565

34 Specific Inhibitors of Renin in Cardiac Therapy / William H. Frishman, Michael H. Shanik, Cherry Lin 589

35 Vasopressin and Vasopressin-Receptor Antagonists in the Treatment of Cardiovascular Disease / William H. Frishman, Marc Klapholz, Naveen Acharya, Adam B. Mayerson 601

36 Hormones as Cardiovascular Drugs: Estrogens, Progestins, Thyroxine, Growth Hormone, Corticosteroids, and Testosterone / William H. Frishman, Mardi Gomberg-Maitland, Ruth Freeman, Denise Park, Atif Qureshi 617

37 Innovative Pharmacologic Approaches to the Treatment of Myocardial Ischemia / William H. Frishman, Avi Retter, John Misailidis, Amanda Ganem, Jessica Sekhon, Rajesh Mohandas, David Khaski, Farooq Sheikh, Donald Orlic, Piero Anversa 655

38 Therapeutic Angiogenesis: A New Treatment Modality for Ischemic Heart Disease / William H. Frishman, Amanda Ganem, Michael A. Nelson, Jonathan Passeri 691

39 Innovative Drug Targets for Treating Cardiovascular Disease: Adhesion Molecules, Cytokines, Neuropeptide Y, Calcineurin, Bradykinin, Urotensin, and Heat Shock Protein / William H. Frishman, Avi Retter, Daniel Mobati, Mariana Fernandez, Sameet A. Palkhiwala, Fay Rim, Andre Scott Jung, Shadi Qasqas, Christos Vavasis 705

40 Pharmacologic Therapies for the Prevention of Restenosis Following Percutaneous Coronary Artery Interventions / William H. Frishman, Brian R. Landzberg, Melvin Weiss 741

41 Gene Transfer in the Cardiovascular System / Jeffrey A. Medin, Peter M. Buttrick 777

42 Inhibition of Myocardial Apoptosis as a Therapeutic Target: Focus on Caspase Inhibition / William H. Frishman, Nils Guttenplan, Christine Leehealey, Edmund H. Sonnenblick, Piero Anversa 789

43 Matrix Metalloproteinases and Their Inhibitors in Cardiovascular Disease / William H. Frishman, Brian A. Ahangar, Sanjai Sinha 797

44 Vasopeptidase Inhibitors: Neutral Endopeptidase Inhibitors and Dual Inhibitors of Angiotensin-Converting Enzyme and Neutral Endopeptidase / William H. Frishman, James Nawarskas, Vikram Rajan, Domenic A. Sica 813

45 The Many Faces of Eicosanoids: Prostaglandins, Leukotrienes, and Other Arachidonate Metabolites / Michael Balazy, John C. McGiff, Michal Laniado-Schwartzman, Domenic A. Sica 821

46 Innovative Medical Approaches for the Treatment of Hyperlipidemia / William H. Frishman, Andrew Y. Choi, Alice Guh 841

Part IV Special Topics 855

47 Use of Alternative/Complementary Medicine in Treating Cardiovascular Disease / Stephen T. Sinatra, William H. Frishman, Stephen J. Peterson, George Lin 857

48 Cardiovascular Drug Interactions / Lionel H. Opie 875

49 Pediatric Cardiovascular Pharmacology / Michael Gewitz, Paul Woolf, William H. Frishman, Joyce Wu 893

50 Drug Treatment of Peripheral Vascular Disease / Robert T. Eberhardt, Jay D. Coffman 919

51 Quality-of-Life Issues with Cardiovascular Drug Therapy / Domenic A. Sica, James A. Schoenberger 935

Appendix 1 Pharmacokinetic Properties of Approved Cardiovascular Drugs 945

Appendix 2 Therapeutic Use of Available Cardiovascular Drugs 961

Appendix 3 Guide to Cardiovascular Drugs Use in Pregnancy and with Nursing 1015

Appendix 4 Dosing Recommendations of Cardiovascular Drugs in Patients with Hepatic Disease and/or Congestive Heart Failure 1021

Appendix 5 Dose Adjustment in Patients with Renal Insufficiency 1025

Appendix 6 Selected Cardiovascular Medications and Gender Issues 1031

Appendix 7 Pharmacokinetic Changes, Route of Elimination, and Dosage Adjustment of Selected Cardiovascular Drugs in the Elderly 1033

Appendix 8 Selected Cardiovascular Medications and Ethnic Issues 1037.

Notes:

Includes bibliographical references and index.

ISBN:

0071369813

OCLC:

49285722